TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 38 OF 56 · NEWEST FIRST

• PTOTOther2024Measurement properties of movement smoothness metrics for upper limb reaching movements in people with moderate to severe subacute stroke.Journal of neuroengineering and rehabilitationSPARC was the most dependable and best tracked upper-limb reaching improvement after subacute stroke. LDLJ was also dependable, but all three time-based smoothness measures were more affected by movement time.
• PTOTOther2024Effects of multidisciplinary inpatient rehabilitation on everyday life physical activity and gait in patients with multiple sclerosis.Journal of neuroengineering and rehabilitationMultidisciplinary inpatient rehabilitation improved walking capacity and self-reported mobility in people with multiple sclerosis, but these gains did not translate into faster or longer walking at home. Mildly disabled patients walked slightly more, while severely disabled patients showed no change in daily activity.
• PTOTRCT2024Motor imagery-based brain-computer interface rehabilitation programs enhance upper extremity performance and cortical activation in stroke patients.Journal of neuroengineering and rehabilitationAdding motor imagery brain-computer interface training to standard therapy improved upper limb function in stroke patients more than standard therapy alone. Brain scans showed increased activation in motor and visual processing areas, which correlated with the physical improvements.
• OTQualitative2024Playing online videogames-more than just entertainment? A qualitative study of virtual social participation in persons with spinal cord injury.Frontiers in rehabilitation sciencesSeven men with spinal cord injury said online videogames helped them stay in touch with friends and family when physical barriers stopped face-to-face contact. They preferred meeting in person, but called gaming better than no social contact.
• PTOTSLPOther2024A scoping review on examination approaches for identifying tactile deficits at the upper extremity in individuals with stroke.Journal of neuroengineering and rehabilitationCurrent stroke touch tests rely on subjective patient responses at rest, often missing the active exploration used in daily life. They rarely compare against healthy controls or check peripheral nerves, limiting their ability to pinpoint where sensory pathways break down.
• PTOTRCT2024Exoskeleton rehabilitation robot training for balance and lower limb function in sub-acute stroke patients: a pilot, randomized controlled trial.Journal of neuroengineering and rehabilitationAdding REX exoskeleton training to standard care improved balance scores more than standard care alone in sub-acute stroke. However, this was a small pilot study of 24 patients, so the results are preliminary and require confirmation in larger trials.
• PTOTCohort2024Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery.Neurorehabilitation and neural repairEarly after stroke, brain activity shows stronger coupling between frontal and motor areas during movement. This elevated coupling linked to better motor scores and recovery, suggesting it may be a compensatory mechanism that decreases as function improves.
• PTOTOther2024Performance of Dietary Behaviors in Chronic Community-Dwelling Stroke Survivors: A Mixed-Methods Study.Occupational therapy in health careStroke survivors rate dietary tasks as highly important but perform them less often and need assistance. Rehabilitation training on meal preparation and shopping is often insufficient. Survivors rely on adaptive equipment and strategies, though many find these underutilized or hard to access.
• PTOTCohort2024Psychosocial reintegration post-traumatic spinal cord injury in Rwanda: An exploratory study.The South African journal of physiotherapyTraumatic spinal cord injury survivors in Rwanda reported poor community reintegration. Men and those with paraplegia fared better than women and those with tetraplegia. These findings highlight the need for rehabilitation services that address gender-specific barriers and support those with higher-level injuries.
• PTOTCohort2024Factors associated with independent ambulation at 3 months after putaminal hemorrhage: an observational study.Journal of physical therapy scienceThree months after putaminal hemorrhage, hip movement ability, cognitive score, and ventricular rupture predicted independent walking. A hemiplegia grade of 6 or higher was the strongest predictor, with 100% specificity for ambulation.
• OTProtocol2023Efficacy and Feasibility of the CO-OP Approach in Parkinson's Disease: RCT Study Protocol.Canadian journal of occupational therapy. Revue canadienne d'ergotherapieNo participant outcomes are reported, so there is nothing here to change practice on.
• PTOTOther2024Automatic gait events detection with inertial measurement units: healthy subjects and moderate to severe impaired patients.Journal of neuroengineering and rehabilitationAn algorithm using foot-worn sensors accurately detected gait events in healthy people and in patients with multiple sclerosis or post-stroke foot deformity. It matched the gold standard without needing extra equipment, offering a practical tool for clinical gait analysis.
• PTOTSLPCohort2024Survival and predictive factors of clinical outcome in patients with severe acquired brain injury.European journal of physical and rehabilitation medicinePatients with severe brain injury who had tracheostomies survived as long as those without, but remained heavily disabled. Younger age predicted better survival and walking ability, yet most patients could not walk or eat by mouth after discharge.
• PTOTSLPQualitative2024Enriching the lives of children with acquired brain injury and their caregivers: experiences from peer mentorship sports camps.Frontiers in rehabilitation sciencesChildren with brain injury and their caregivers described a sports camp as a way to manage fatigue, build confidence, and reduce isolation. Caregivers reported becoming less overprotective and more hopeful after meeting peer mentors who shared similar experiences.
• OTOther2024Bimanual coordination and spinal cord neuromodulation: how neural substrates of bimanual movements are altered by transcutaneous spinal cord stimulation.Journal of neuroengineering and rehabilitationTranscutaneous cervical spinal cord stimulation did not improve most reaching tasks in 12 healthy adults, but it lowered movement error during a bimanual common-goal task. Brain activity changes were inconsistent, and the study did not test people with spinal cord injury or stroke.
• PTOTSurvey2024Orthotist involvement in early gait rehabilitation after stroke: A cross-sectional survey of orthotists in the United Kingdom.Prosthetics and orthotics internationalMost orthotists felt they should be routinely involved in early stroke gait rehabilitation without a specific referral, but only 5% reported being involved that way. They were confident in prescribing ankle-foot orthoses but less confident advising on broader therapy.
• PTOTSLPOther2024Co-design of a walking activity intervention for stroke survivors.Frontiers in rehabilitation sciencesStroke survivors rarely walk just for exercise. They need walking linked to valued social goals, supported by objective step feedback and carer involvement. A new co-design toolbox provides these elements, but efficacy is untested.
• PTOTSurvey2024Needs Assessment of Self-Management for Individuals With Chronic Spinal Cord Injury/Disease.OTJR : occupation, participation and healthPeople with chronic spinal cord injury ranked virtual meetings and group discussions as the most important features for a self-management program. Psychological health and coping were rated the top content priority, far ahead of respiratory or autonomic issues.
• PTOTCase-Control2024Robot-aided assessment and associated brain lesions of impaired ankle proprioception in chronic stroke.Journal of neuroengineering and rehabilitationMost adults with chronic stroke showed impaired ankle position and motion sense on robotic testing. These deficits were linked to lesions in the insula and temporoparietal regions. Standard clinical scales may miss these subtle proprioceptive losses that affect balance.
• PTOTSLPQualitative2024Experiences of chain of care and rehabilitation after stroke: a qualitative study of persons discharged to skilled nursing facilities before returning home.Journal of rehabilitation medicineStroke survivors discharged to skilled nursing facilities reported lacking information on fatigue and prevention, and felt excluded from rehabilitation planning. They valued immediate provision of aids upon returning home, but faced delays in mobility services and inconsistent training support.
• OTRCT2024Activation changes in patients with post-stroke cognitive impairment receiving intermittent theta burst stimulation: A functional near-infrared spectroscopy study.NeuroRehabilitationIn adults with post-stroke cognitive impairment, adding intermittent theta burst stimulation to 30 cognitive training sessions showed greater gains in cognition and daily independence than cognitive training alone. The brain stimulation group also showed increased activation during a word task.
• PTOTSLPCohort2024Utilization and features of rehabilitation and health services for persons with spinal cord injury.European journal of physical and rehabilitation medicineIn Swiss spinal cord injury rehab, nursing, physiotherapy and occupational therapy take the most time. Patients with higher cervical injuries and lower function receive far more services per day, while those with better function receive fewer.
• PTOTCohort2024Perceived and physiological strains of societal participation in people with multiple sclerosis: a real-time assessment study.Journal of rehabilitation medicineFor people with MS, how strenuous an activity feels does not predict how hard their heart works. Perceived strain was linked to fatigue, not physiology. Clinicians should treat fatigue and perceived effort directly, rather than assuming physical exertion drives the complaint.
• PTOTOther2024Trend change analysis of postural balance in Parkinson's disease discriminates between medication state.Journal of neuroengineering and rehabilitationTrend change analysis detected differences between medication states in Parkinson's disease that standard sway measures missed. However, neither method distinguished patients from healthy controls during quiet standing.
• PTOTSLPCohort2024Comparison of motion sensor and heart rate monitor for assessment of physical activity intensity in stroke outpatient rehabilitation sessions: an observational study.Journal of rehabilitation medicineMotion sensors and heart rate monitors give very different readings of how hard stroke patients work in rehab. One device showed no moderate activity while the other showed plenty. Do not rely on a single device to judge session intensity.
• PTOTSLPRCT2024Effect of repetitive peripheral magnetic stimulation of the common fibular nerve on the soleus muscle Hoffmann reflex.Journal of physical therapy scienceRepetitive magnetic stimulation of the common fibular nerve reduced soleus muscle H-reflex amplitude in healthy men, suggesting increased spinal inhibition. However, the control group also showed changes, and the clinical effect on spasticity or function in patients was not tested.
• PTOTSLPCase Report2024Implementing neuropsychological rehabilitation following severe traumatic brain injury in a low-to-middle income country: a case report.Frontiers in rehabilitation sciencesA man with severe brain injury used iPad checklists and loud calendar alerts to regain daily independence, but standard cognitive tests showed no improvement. Family reported better task completion and reduced conflict, while the patient’s physical function actually worsened. This single case cannot prove the method works.
• OTQualitative2023'It is never-ending work': Colombian occupational therapists' experiences of working in stroke rehabilitation.The British journal of occupational therapyColombian occupational therapists described stroke care as uneven: insurers and short hospital stays caused delays and lost rehabilitation, while a Bogotá centre of excellence was described as offering early, consistent occupational therapy. They also said colleagues often mistake occupational therapy for childlike play.
• PTOTOther2024Validity and reliability of the chronic composite XA, an upper limb motor assessment using Active Range of Motion in patients with chronic stroke.European journal of physical and rehabilitation medicineIn 28 chronic stroke patients, a quick arm movement score against resistance tracked standard arm tests and stayed stable on retesting. Adding shoulder and forearm measurements improved the score. A gain above 64 degrees was needed to call change real.
• PTOTSLPCohort2024Stroke survivors' long-term participation in paid employment.Work (Reading, Mass.)Half of stroke survivors with pre-stroke jobs still had employment contracts at 30 months, but many were on sick leave. Those who stayed in the workforce reported better quality of life and communication, yet non-work participation remained restricted and less satisfying.
• PTOTSurvey2024Patient-reported outcome survey of user-experiences in the spinal cord injured-community with MPPT for treating wounds and pressure injuries and for controlling soft tissue infection caused by osteomyelitis.Frontiers in rehabilitation sciencesSpinal cord injury patients reported a 100% closure rate for wounds and control of fistula symptoms using MPPT powder. Most treated themselves without nursing support. These are self-reported experiences from a small group, not proof of efficacy.
• PTOTOther2024Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke.Journal of neuroengineering and rehabilitationAdding brain activation data to digital rehab scores improved the accuracy of classifying stroke patients' motor impairment severity. Patients with limited function showed increased brain activity in motor and planning areas, while those with better function showed no significant activation.
• OTQualitative2023Exploring the usability of a smartphone application to monitor fatigue and activity for people with acquired brain injury.The British journal of occupational therapySeven people with acquired brain injury found a fatigue-tracking app easy to use, especially the energy battery metaphor. Carrying a second phone and quiet notifications were major barriers. Self-monitoring changed how they understood fatigue, but sensor data failed because phones were kept in bags.
• PTOTCase-Control2024Inter-joint coordination with and without dopaminergic medication in Parkinson's disease: a case-control study.Journal of neuroengineering and rehabilitationPeople with Parkinson's disease showed reduced knee movement and delayed hip flexion during walking, particularly at preferred speeds. Dopaminergic medication improved hip kinematics only at preferred speed and did not resolve these coordination deficits. Walking faster than usual may improve gait regularity.
• PTOTSystematic Review2023Effectiveness of Robotics in Stroke Rehabilitation to Accelerate Upper Extremity Function: Systematic Review.Occupational therapy internationalRobot-assisted therapy did not significantly speed up overall upper limb recovery compared to conventional therapy alone. However, gains were faster in the first 25 hours, suggesting robots may help early in rehabilitation before progress plateaus.
• OTQualitative2023The Lived Experience of Persons with Spinal Cord Injuries Engaging in Remote Work: A South African Perspective.Occupational therapy internationalFour people with spinal cord injuries in remote jobs described remote work as allowing schedule changes, better bladder and bowel management, and less commuting. They also reported social isolation, less mobility, and dependence on employer support.
• PTOTSurvey2024An International and Multidisciplinary Consensus on the Labeling of Spatial Neglect Using a Modified Delphi Method.Archives of rehabilitation research and clinical translationExperts reached consensus on 'spatial neglect' as the preferred label, because 'unilateral' implies one-sided deficits while impairment follows a gradient. Use it when communicating the diagnosis.
• PTOTMeta-Analysis2024Are Middle- or Older-Aged Adults With a Spinal Cord Injury Engaging in Leisure-Time Physical Activity? A Systematic Review and Meta-Analysis.Archives of rehabilitation research and clinical translationLeisure activity in adults over 45 with spinal cord injury varies wildly. While the average moderate-to-heavy activity was 173 minutes per week, between 27% and 64% of participants reported doing none at all. This gap means you cannot assume your patients are active enough to protect their heart health.
• PTOTPilot2024Adapting the Multiple Sclerosis Functional Composite for Telehealth Administration Using Videoconference Delivery: Methodological Considerations and Interrater Reliability.Archives of rehabilitation research and clinical translationTwo raters agreed on scores from the tele-MSFC, participants accepted it, and no adverse events occurred in 61 adults with MS. It is not ready as a trial endpoint.
• OTCohort2023Consistency between two subjective assessments of activities of daily living: Patient- and occupational therapist-reported judgments.Hong Kong journal of occupational therapy : HKJOTIn subacute stroke, patient and OT ADL ability ratings matched moderately, but their ratings of change matched poorly. At discharge, OTs judged ADL ability higher than patients and than actual ADL performance.
• OTOther2023Assessment of sensory impairment of the upper limb post-stroke by occupational therapists within the acute setting: A mixed methods study exploring current clinical practice.The British journal of occupational therapySurveyed acute stroke occupational therapists reported standardised sensory assessment use: always 3, usually 11, sometimes 21, rarely 33, never 13. Time and resources made full assessment hard, despite therapists seeing it as their role.
• PTOTSLPSystematic Review2024Occupational therapy and cooking: A scoping review and future directions.Scandinavian journal of occupational therapyCooking is a core occupational therapy activity used across the lifespan for assessment and intervention. The literature shows therapists use it to build skills and address cognitive or environmental barriers, but rigorous evidence for its specific health effects remains limited.
• PTOTCohort2024Factors influencing the prognosis of patients with acute cerebral infarction who received usual care: a multicenter prospective cohort study.Journal of physical therapy scienceIn patients with acute cerebral infarction receiving usual care, poor functional outcome was predicted by higher initial stroke severity (NIHSS >4) and reinfarction, not by the timing of first mobilization. Age and rehabilitation intensity were not independent predictors.
• PTOTQualitative2024Rehabilitation Professionals' Perspectives on Human Rights, Disability, and Science: A Qualitative Study.Archives of rehabilitation research and clinical translationMost rehabilitation professionals for spinal cord injury did not know UN human rights conventions, though all knew the Americans with Disabilities Act. They saw barriers like equipment denial and transport as policy issues, not rights violations, yet were open to learning how to frame them as rights.
• PTOTSLPOther2024Machine learning for automating subjective clinical assessment of gait impairment in people with acquired brain injury - a comparison of an image extraction and classification system to expert scoring.Journal of neuroengineering and rehabilitationA computer model scored arm movement abnormality during walking as consistently as three experienced physiotherapists. It correctly identified impaired versus unimpaired movement in 84% of cases, matching human judgment without the usual disagreement between different clinicians.
• PTOTQualitative2024Technology Use for Home-Based Stroke Rehabilitation in Switzerland From the Perspectives of Persons Living With Stroke, Informal Caregivers, and Therapists: Qualitative Interview and Focus Group Study.JMIR rehabilitation and assistive technologiesStroke survivors and therapists in Switzerland want home technology but lack clear guidance on which tools to use. Reimbursement uncertainty and a heavy burden on informal caregivers hinder adoption, with survivors relying on therapists to filter options.
• PTOTCohort2024Influence of virtual reality and task complexity on digital health metrics assessing upper limb function.Journal of neuroengineering and rehabilitationFor people with MS, virtual reality assessments were more responsive to rehabilitation changes than physical tasks, despite the physical tasks having lower variability and higher usability. Neither method proved significantly more reliable or valid for detecting upper limb function.
• OTCase Report2024Efficacy of mental practice on paralyzed upper extremity function in the acute phase of stroke: a case study.Journal of physical therapy scienceA patient with acute stroke palsy received mental practice combined with mirror therapy. Her upper limb function scores improved from zero to 25 on the Fugl-Meyer assessment. This single case does not prove the treatment works, but suggests early combined therapy is feasible.
• OTOther2023Requirements for Universally Accessible Upper-Body Exercise Equipment: The Case of People with Spinal Cord Injuries in Korea.Occupational therapy internationalFive wheelchair users tested four upper-body machines. Transfers were slow and risky on strength equipment, while arm ergometers were easier. Low satisfaction scores for posture support highlight the need for adjustable seats, clear instructions at eye level, and stable wheelchair fixes.
• PTOTSLPSystematic Review2024Leisure Engagement Among People Living With Acquired Brain Injury: A Scoping Review.OTJR : occupation, participation and healthPeople with acquired brain injury engage less in leisure than before, shifting toward sedentary, solitary, home-based activities. Transport, fatigue, and cognitive limits block community participation. Assess these specific barriers and environmental factors, not just physical recovery, to support meaningful re-engagement.