TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 36 OF 56 · NEWEST FIRST

• PTOTPilot2024Reminiscent music therapy combined with robot-assisted rehabilitation for elderly stroke patients: a pilot study.Journal of neuroengineering and rehabilitationAdding reminiscent music to robot therapy improved self-efficacy and positive emotions more than robot therapy or usual care alone. However, the primary outcome of daily living activities showed no significant difference between the three groups. All groups improved from their own baselines.
• PTOTCohort2024Prevalence of Arm Weakness, Pre-Stroke Outcomes and Other Post-Stroke Impairments Using Routinely Collected Clinical Data on an Acute Stroke Unit.Neurorehabilitation and neural repair34.8% of 463 stroke patients at one acute hospital had upper limb weakness at a median of 1.0 day post-stroke. No one with severe weakness went home directly.
• PTOTSLPMeta-Analysis2024Effects of physical exercise interventions on balance, postural stability and general mobility in Parkinson's disease: a network meta-analysis.Journal of rehabilitation medicineBalance exercises were the only intervention to improve all measured outcomes of mobility and stability. Dance, alternative exercises like Tai Chi, and resistance training also showed significant benefits. Combining these elements in a multimodal programme is likely more effective than any single exercise type alone.
• PTOTOther2024Relative aerobic load of walking in people with multiple sclerosis.Journal of rehabilitation medicineWalking at a comfortable pace demands 60% of peak aerobic capacity for people with MS, a level considered high. Almost one-third exceed their ventilatory threshold, meaning daily walking causes physiological exhaustion. This suggests patients may be walking too fast for their fitness.
• PTOTQualitative2024Patient experiences of physical activity and inactivity in the stroke unit: an interview study.Journal of rehabilitation medicineStroke patients described wanting to move and be independent, but staying in bed often felt invisible. They said staff who explained exercises, prioritized patients over routines, and encouraged movement helped them get up and feel respected.
• PTOTSLPRCT2023Efficacy of Transcranial Direct Current Stimulation Combined with Conventional Swallowing Rehabilitation Training on Post-stroke Dysphagia.DysphagiaAdding 1 mA tDCS to standard swallowing therapy improved swallowing scores more than standard therapy alone at 3 months. However, both groups received extensive concurrent treatments, so the specific benefit of tDCS cannot be isolated from the rest of the care.
• PTOTOther2024Freezing of gait assessment with inertial measurement units and deep learning: effect of tasks, medication states, and stops.Journal of neuroengineering and rehabilitationA deep learning model using leg sensors matched expert ratings of freezing of gait severity in Parkinson's disease. It worked well for standard walking and turning tests, but only if trained on the specific task being tested. It also distinguished freezing from voluntary stops if stops were included in training.
• OTCohort2024Influence of Perceptual Load on Attentional Orienting in Post-Stroke Fatigue: A Study of Auditory Evoked Potentials.Neurorehabilitation and neural repairStroke survivors with high fatigue showed reduced brain responses to unexpected sounds only when background noise was present. This suggests high perceptual load impairs attentional orienting in fatigue, even when physical performance and early sensory processing remain normal.
• PTOTSLPQualitative2024Spatial Neglect: An Exploration of Clinical Assessment Behaviour in Stroke Rehabilitation.Clinical rehabilitationStroke clinicians rarely use standardised spatial neglect assessments because they view it as a visual problem rather than a multisensory one. They lack knowledge of functional tools and feel assessment is outside their scope. Barriers include time, cost, and equipment. Clinicians want short, flexible tests and online training with practical demos.
• PTOTNarrative Review2024Optimizing lower limb rehabilitation: the intersection of machine learning and rehabilitative robotics.Frontiers in rehabilitation sciencesMachine learning can make lower limb rehabilitation robots more accurate and personalized, but high costs and 'black box' algorithms currently block clinical use. Therapists should view these tools as emerging aids requiring explanation and trust-building, not proven replacements for manual care.
• PTOTSLPMeta-Analysis2024Effects of transcranial direct current stimulation alone and in combination with rehabilitation therapies on gait and balance among individuals with Parkinson's disease: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitationtDCS improved walking rhythm and reduced freezing of gait, but did not significantly change walking speed or stride length. It also helped balance on the Timed Up and Go test. No single optimal protocol for dose or placement has been established.
• PTOTOther2024Accuracy and Reliability of Remote Categorization of Upper Limb Outcome After Stroke.Neurorehabilitation and neural repairRemote video assessment matched in-person upper limb outcome for 88% at 3 months and 96% at 6 months. It was less accurate at the chronic stage, 75% and 79%, and for the Good and Limited categories.
• PTOTOther2024A neuromechanical model characterizing the motor planning and posture control in the voluntary lean in Parkinson's disease.Journal of neuroengineering and rehabilitationPD patients lean slower and with stiffer ankles, especially backward. They also make smaller preparatory movements before leaning. These model parameters correlate with clinical scores like UPDRS and Functional Reach, offering a way to quantify specific balance deficits.
• PTOTSLPPilot2024A Digital Intervention to Promote Self-Management Self-Efficacy Among Community-Dwelling Individuals With Stroke: Pilot Randomized Controlled Trial.JMIR rehabilitation and assistive technologiesA 12-week text-messaging and coaching program improved stroke survivors' confidence in managing home, work, and social activities. Retention was high, but the small sample and unblinded design mean this shows feasibility, not proven effectiveness.
• PTOTSLPCohort2024Identifying profiles of stroke patients benefitting from additional training: a latent class analysis approach.Journal of rehabilitation medicineAdditional training improved daily living scores only for a specific group: patients aged 65-84 with right-side paralysis and moderate dependence. For this group, combining self-exercise with staff-led training worked best. Other patient profiles showed no significant benefit from these additions.
• PTOTSLPOther2024Family caregivers improve the diagnostic accuracy of disorders of consciousness: from remote to near-bed auditory stimulation.European journal of physical and rehabilitation medicineHaving a family caregiver deliver verbal instructions during consciousness assessments, whether in the room or via video, helped clinicians identify higher levels of consciousness in patients with severe brain injury. This method reduced the risk of misdiagnosing patients as unresponsive.
• PTOTSLPCohort2024Clinical Features and Voxel-Based-Symptom-Lesion Mapping of Silent Aspiration in Acute Infratentorial Stroke.DysphagiaSilent aspiration occurred in 40.5% of acute infratentorial stroke patients, doubling pneumonia risk. Lesion location did not predict it. Do not rely on stroke severity scores alone; these patients need FEES assessment regardless of how mild their deficits appear.
• PTOTSLPOther2024Access to inpatient mood management services after stroke in Australian acute and rehabilitation hospitals.Clinical rehabilitationMood screening rates in Australian stroke hospitals increased over ten years but remain low, with only 33% of acute patients screened by 2021. Access to psychologists improved in rehabilitation settings but stalled in acute care, leaving older patients and those needing interpreters at higher risk of being missed.
• PTOTSLPCohort2024Trends in the Characteristics and Outcomes of Older Medicare Patients With Traumatic Brain Injury Treated in Inpatient Rehabilitation Facilities: 2013 to 2018.Archives of physical medicine and rehabilitationOlder Medicare patients with recent traumatic brain injury in inpatient rehabilitation increased 28.2% from 2013 to 2018. They were more often male, had more comorbidities, and more were discharged home.
• PTOTOther2024A Novel, Wearable Inertial Measurement Unit for Stroke Survivors: Validity, Acceptability, and Usability.Archives of physical medicine and rehabilitationWearable sensors counted steps and active arm time close to video and research systems in 30 stroke survivors. Most found them comfortable, but 19 could not put on or remove a wrist sensor, so usability needs simpler wristbands.
• PTOTSLPOther2024Development of a Job Retention Vocational Rehabilitation Intervention for People with Multiple Sclerosis Following the Person-Based Approach.Clinical rehabilitationA new job retention programme for multiple sclerosis was designed with patients and clinicians. It involves up to 10 hours of tailored support over three months, focusing on reasonable adjustments, symptom management, and legal rights.
• PTOTRCT2024The Utilization of Forced-Rate Cycling to Facilitate Motor Recovery Following Stroke: A Randomized Clinical Trial.Neurorehabilitation and neural repairAdding 45 minutes of motor-assisted cycling before upper-limb practice did not improve arm function more than practice alone. However, the cycling group walked significantly farther and had better cardiovascular fitness, suggesting cycling benefits legs and heart even if it does not boost arm recovery.
• PTOTSLPPilot2024Coproduction and Usability of a Smartphone App for Falls Reporting in Parkinson Disease.Physical therapyThirteen people with Parkinson disease tested a new app for logging falls over six months. They found it easy to use and preferred it to paper diaries, especially because they could type or speak instead of write. It helped some spot fall patterns, but not all.
• PTOTSLPCase Report2024A case study of using community-based consensus methods to facilitate shared decision-making among a spinal cord injury network.Frontiers in rehabilitation sciencesPeople with spinal cord injury, clinicians and researchers shaped the Ontario SCI Alliance's strategic plan through two Delphi surveys and a retreat. The process generated five themes on inclusion, partnership, design, communication and sustainability, and led to policy changes including a catheter coverage campaign.
• PTOTRCT2024Effects of the powerball® system on muscle strength, coordination, fatigue, functionality and quality of life in people with multiple sclerosis. A randomized clinical trial.Journal of neuroengineering and rehabilitationAdding PowerBall to physiotherapy did not improve grip strength, the main outcome, versus physiotherapy alone in people with multiple sclerosis. Coordination improved in both groups, so adding it did not show a clear benefit.
• PTOTOther2024Resting-state cortical electroencephalogram rhythms and network in patients after chronic stroke.Journal of neuroengineering and rehabilitationIn chronic stroke, slow brain waves dominate the injured hemisphere while fast beta waves remain linked to arm function. High beta power and specific delta network patterns on the healthy side correlated with better hand movement, but asymmetry itself did not predict recovery.
• PTOTRCT2024Effects of motor imagery-based neurofeedback training after bilateral repetitive transcranial magnetic stimulation on post-stroke upper limb motor function: an exploratory crossover clinical trial.Journal of rehabilitation medicineIn 20 post-stroke adults, adding motor imagery neurofeedback to bilateral rTMS was associated with better upper limb movement scores than rTMS alone, but the trial had carry-over, no blinding, and usual rehab continued.
• OTCohort2024Stressful life events are associated with self-reported fatigue and depressive symptoms in patients with mild traumatic brain injury.Journal of rehabilitation medicinePatients with mild brain injury did not differ from patients with ankle fracture in reported fatigue or depressive symptoms. In the mild brain injury group, more recent stressful life events were associated with more reported fatigue and depressive symptoms.
• PTOTSLPPilot2024Community-based exercise program, self-reported health-related symptoms, and quality of life in persons with traumatic brain injury 45 + years old.NeuroRehabilitationIn 20 adults with moderate-to-severe brain injury, a 12-week community-based aerobic program improved self-reported cognitive health and sleep quality compared to stretching. Global quality of life, emotional health, and social health showed no significant difference between groups.
• PTOTSLPOther2024The reliability, validity and clinical utility of the Clinical Outcomes in Routine Evaluation - ten-item version (CORE-10) in post-acute patients with stroke.Clinical rehabilitationThe CORE-10 is a valid, free, and quick mood screen for post-acute stroke inpatients. A change of 9 points indicates 90% confidence in real clinical improvement or deterioration, while a score of 12 or higher marks clinically significant distress.
• PTOTCohort2023Proactive outcome monitoring and standardisation of physiotherapy stroke rehabilitation - A retrospective functional outcomes analysis of Accelerated Stroke Ambulation Programme (ASAP).Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoStroke patients in a standardised rehab programme gained more mobility points than those in traditional care, but balance and daily living scores showed no clear difference. The programme relies on data-driven decision support rather than therapist preference alone.
• PTOTSLPOther2024Revision of the brief international classification of functioning, disability and health core set for multiple sclerosis: a study of the comprehensive icf core set for multiple sclerosis with participants referred for work ability assessment.Journal of rehabilitation medicineIn people with MS referred for work ability assessment, memory and temperament impairments were common but missed by the current Brief ICF Core Set. The study suggests replacing higher-level cognitive and emotional categories with memory and temperament to better capture disability.
• PTOTSLPSystematic Review2023Cognitive-motor dual-task interference in Alzheimer's disease, Parkinson's disease, and prodromal neurodegeneration: A scoping review.Gait & postureWalking while doing a mental task causes bigger drops in gait and thinking speed for people with Alzheimer's or Parkinson's than for healthy adults. This interference worsens as disease progresses, but no single test predicts it reliably yet.
• PTOTCohort2023Using the Standing and Walking Assessment Tool at Discharge Predicts Community Outdoor Walking Capacity in Persons With Traumatic Spinal Cord Injury.Physical therapyDischarge SWAT stage 3B or higher predicted outdoor walking one year later. Stage 4 predicted independent walking without aids. Lower stages predicted non-walking. Use these cutoffs to guide equipment prescription and discharge planning for spinal cord injury patients.
• OTCohort2024Dynamics of Perceived Social Isolation, Secondary Conditions, and Daily Activity Patterns Among Individuals With Stroke: A Network Analysis of Ecological Momentary Assessment Data.Archives of physical medicine and rehabilitationAdults after stroke who reported feeling worthless were more likely to report perceived social isolation later. Isolation also happened alongside being home and alone. In one model, isolation was followed by stress, then leaving home.
• OTSurvey2024Factors associated with fatigue among people who have returned to work after stroke: an exploratory study.Journal of rehabilitation medicineAmong people back at work one year after stroke, 43% reported fatigue. The strongest links were to perceived memory and thinking problems, high job demands and low control at work. This survey shows associations, not causes.
• PTOTRCT2024360° immersive virtual reality-based mirror therapy for upper extremity function and satisfaction among stroke patients: a randomized controlled trial.European journal of physical and rehabilitation medicineWith conventional physical therapy, 360° immersive mirror therapy improved upper limb movement more than traditional mirror therapy. Traditional mirror therapy did not improve the upper limb motor score more than conventional physical therapy alone. Patients liked the 360° version more.
• PTOTSLPPilot2024Feasibility of a Self-directed Upper Extremity Training Program to Promote Actual Arm Use for Individuals Living in the Community With Chronic Stroke.Archives of rehabilitation research and clinical translationFifteen people with chronic stroke completed a self-directed home arm training program. While retention and safety were high, only a third met the daily practice duration target. Participants reported improved arm use and satisfaction, but the study was not designed to prove the training caused these changes.
• PTOTOther2024Accuracy of Video-Based Gait Analysis Using Pose Estimation During Treadmill Walking Versus Overground Walking in Persons After Stroke.Physical therapySagittal video of overground walking tracked hip and knee motion more accurately than treadmill video. Treadmill video matched overground for step length and time but struggled with ankle angles and asymmetry. Use sagittal overground views for kinematics if space allows.
• PTOTSLPOther2024Concurrent validity of walking speed measured by a wearable sensor and a stopwatch during the 10-meter walk test in individuals with stroke.Gait & postureWearable sensors measured walking speeds about 0.07 m/s slower than a stopwatch in people with stroke. You cannot use these two methods interchangeably. If you switch tools mid-rehab, the drop in speed might be measurement error, not the patient getting worse.
• OTSurvey2024Financial Capability and Financial Well-Being Challenges and Vulnerabilities of Adults Living With Acquired Brain Injury: A Pilot Survey.Archives of rehabilitation research and clinical translationAdults with acquired brain injury described needing help with money tasks, and some felt financially exploited. Close others reported stress with financial forms. This pilot survey describes challenges, not tested interventions.
• PTOTRCT2024A wearable system for visual cueing gait rehabilitation in Parkinson's disease: a randomized non-inferiority trial.European journal of physical and rehabilitation medicineWearable knee-pad visual cues were not inferior to floor stripes for gait in Parkinson's. Both groups improved similarly on the primary outcome. The device was rated easy and motivating by most patients, supporting its use when floor cues are impractical.
• PTOTSLPSystematic Review2024Prevalence of dual sensory impairment in veterans: a rapid systematic review.Frontiers in rehabilitation sciencesReported prevalence of dual sensory impairment in veterans varied widely from 5.0% to 34.6%. This inconsistency stems from different definitions and measurement methods, not necessarily true differences in risk.
• PTOTOther2024Extended reality to assess post-stroke manual dexterity: contrasts between the classic box and block test, immersive virtual reality with controllers, with hand-tracking, and mixed-reality tests.Journal of neuroengineering and rehabilitationVirtual and mixed-reality box-and-block tests correlate strongly with the traditional test in stroke survivors, but score lower. Hand-tracking and mixed-reality versions were rated as more usable and similar in difficulty to the classic test than the controller-based version.
• OTCohort2024Trajectories of fatigue and related outcomes following mild acquired brain injury: a multivariate latent class growth analysis.Journal of rehabilitation medicineAfter mild brain injury, 53% had mild, decreasing fatigue and no other problems. 29% had persistent fatigue, cognitive complaints and low participation satisfaction. 11% had persistent fatigue with mood and cognitive complaints. 7% had improving fatigue with mood problems.
• PTOTCohort2024Exploring the Major Barriers to Physical Activity in Persons With Multiple Sclerosis: Observational Longitudinal Study.JMIR rehabilitation and assistive technologiesLess active people with MS reported needing more family and friend support than active peers. Higher depression and fatigue scores linked to more perceived barriers. However, barrier scores did not predict whether someone hit standard step or activity thresholds.
• PTOTPilot2024Neck muscle spasticity in patients with disorder of consciousness: a pilot study.European journal of physical and rehabilitation medicineNeck spasticity is very common in patients with severe brain injury and disorders of consciousness, affecting 91.7% of those studied. In patients who are unresponsive, severe neck stiffness predicted worse neurological and functional recovery after six months of rehabilitation.
• PTOTSLPMeta-Analysis2024The effects of visual skills training on cognitive and executive functions in stroke patients: a systematic review with meta-analysis.Journal of neuroengineering and rehabilitationVisual skills training improved global cognition and daily living tasks, but showed only small effects on executive functions. The evidence is inconsistent and often confounded by other therapies, so do not assume visual training alone drives these gains.
• PTOTSLPCohort2023Treatment of balance with Computerised Dynamic Posturography therapy in chronic hemiplegic patients.The South African journal of physiotherapyAdding computerized balance training to standard therapy did not improve overall balance scores in stroke patients with a history of falls. Only one specific sensory test score improved. Standard therapy alone produced similar changes, so the computer's added value is unproven.
• PTOTCase Report2024Use of an upright power wheelchair in spinal cord injury: a case series.Frontiers in rehabilitation sciencesFour people with spinal cord injuries used a standing wheelchair for 12 weeks. It was safe and users felt stable and comfortable standing, but transferring was difficult. Bowel, bladder, and pain outcomes varied widely between individuals, with no consistent improvement.