TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 10 OF 56 · NEWEST FIRST

• PTOTSLPSurvey2019Prevalence of five lifestyle risk factors among U.S. adults with and without stroke.Disability and health journalStroke survivors are significantly less likely to exercise, smoke, or eat poorly compared to those without stroke. They also cluster multiple risk factors, with higher rates of having 2 to 5 lifestyle risks, suggesting targeted prevention efforts are needed.
• PTOTSLPSystematic Review2019A systematic review of measures of adherence to physical exercise recommendations in people with stroke.Clinical rehabilitationNo validated tools exist to measure adherence to exercise after stroke. Clinicians currently rely on diaries and surveys with no proven accuracy. Do not assume patient-reported completion matches actual performance, as these methods lack evidence of validity.
• OTRCT2018Effects of a virtual reality video game exercise program on upper extremity function and daily living activities in stroke patients.Journal of physical therapy scienceAdding Wii video-game exercise to usual stroke therapy did not improve standard arm/hand test scores more than usual therapy alone. The daily-living questionnaire showed a group difference, but the paper's numbers for it are unclear.
• PTOTSystematic Review2018Assistive Technology for the Upper Extremities After Stroke: Systematic Review of Users' Needs.JMIR rehabilitation and assistive technologiesStroke survivors, carers and clinicians prioritise upper-limb assistive devices that are easy to use, fit home life, support real tasks, and feel safe. Cost, evidence and trust decide adoption.
• PTOTSLPOther2018The effect of comprehensive physiotherapy-based rehabilitation on stooped posture in Parkinson's disease.Journal of physical therapy scienceIn Parkinson's patients with stooped posture, inpatient comprehensive physiotherapy improved trunk bending angles significantly more than usual home care. However, the rehabilitation group received intensive multi-disciplinary therapy, so the specific contribution of physiotherapy alone cannot be separated.
• OTCohort2019A Comparison of Satisfaction With Life and the Glasgow Outcome Scale-Extended After Traumatic Brain Injury: An Analysis of the TRACK-TBI Pilot Study.The Journal of head trauma rehabilitationSix months after TBI, 31% had a mismatch between functional recovery and life satisfaction. Depression at six months was linked to lower satisfaction. Ask about mood, not just recovery.
• OTCohort2019Group Differences Among Caregivers of Civilians and Service Members or Veterans With Traumatic Brain Injury.Archives of physical medicine and rehabilitationCaregivers of service members or veterans with TBI were more often younger spouses, cared for people injured longer ago, and reported more adjustment problems in the person with TBI and feeling trapped. These group differences do not show cause.
• OTRCT2018Generalizing remotely supervised transcranial direct current stimulation (tDCS): feasibility and benefit in Parkinson's disease.Journal of neuroengineering and rehabilitationTen home tDCS sessions paired with cognitive training were feasible in 16 people with Parkinson's disease. Fatigue, sleep, visual learning and reaction time scores did not show a clear change; negative affect scores decreased, but this was a small pilot.
• PTOTRCT2018Evaluation of the Keeogo exoskeleton for assisting ambulatory activities in people with multiple sclerosis: an open-label, randomized, cross-over trial.Journal of neuroengineering and rehabilitationPeople with multiple sclerosis walked and climbed stairs slower while wearing the Keeogo exoskeleton compared to not wearing it. However, using the device at home for two weeks improved their unassisted walking and stair performance, suggesting a conditioning benefit rather than immediate assistance.
• OTSLPQualitative2019'I kind of figured it out': the views and experiences of people with traumatic brain injury (TBI) in using social media-self-determination for participation and inclusion online.International journal of language & communication disordersPeople with TBI used social media to stay connected, but many lurked, felt overwhelmed or fatigued, and learned platforms by trial and error. They lacked direct support and needed prompt, relevant help.
• PTOTNarrative Review2018Transcranial direct current stimulation for promoting motor function in cerebral palsy: a review.Journal of neuroengineering and rehabilitationtDCS paired with training was linked to better walking speed, balance and mobility in children and adolescents with cerebral palsy, but upper limb motor gains remain unclear.
• OTSLPOther2018Capturing Expert Knowledge for the Personalization of Cognitive Rehabilitation: Study Combining Computational Modeling and a Participatory Design Strategy.JMIR rehabilitation and assistive technologiesA free web tool can generate personalized paper-and-pencil cognitive tasks for people after stroke. It uses expert ratings of task demands, not patient outcomes, so it may help therapists choose tasks but does not show improved recovery.
• PTOTPilot2019A Single Session of Robot-Controlled Proprioceptive Training Modulates Functional Connectivity of Sensory Motor Networks and Improves Reaching Accuracy in Chronic Stroke.Neurorehabilitation and neural repairChronic stroke patients judged arm position more accurately after one session of passive arm movements with left/right judgment and feedback. Six patients who could actively reach moved in straighter paths. This was small and uncontrolled, so it is not proof of lasting recovery.
• OTCohort2019Healthcare Utilization and Missed Workdays for Parents of Children With Traumatic Brain Injury.The Journal of head trauma rehabilitationParents of children with traumatic brain injury missed more work and used more healthcare services than parents of children with other injuries, especially in the first 6 months. The burden grew with injury severity.
• PTOTPilot2018User-centered practicability analysis of two identification strategies in electrode arrays for FES induced hand motion in early stroke rehabilitation.Journal of neuroengineering and rehabilitationBoth semi-automatic and automatic electrode-array search methods found stimulation areas for hand opening in sub-acute stroke patients, but finger flexion was less reliable. The semi-automatic search was faster, and neither method was clearly preferred.
• OTRCT2019The effects of time-use intervention on the quality of life of outpatients with chronic stroke.Journal of physical therapy scienceStroke outpatients who received weekly counselling to balance their daily routines reported better quality of life than those given usual therapy and free time. The intervention helped them choose and track two new activities per week.
• OTCohort2019Use of a multilayer perceptron to create a prediction model for dressing independence in a small sample at a single facility.Journal of physical therapy scienceA neural-network model predicted which stroke patients would dress independently at discharge better than conventional models in 82 patients, but it was tested only at a single facility and not externally.
• OTOther2019A modified standardized nine hole peg test for valid and reliable kinematic assessment of dexterity post-stroke.Journal of neuroengineering and rehabilitationStroke participants showed slower, less smooth hand movements on a standardized nine-hole peg test than controls. The movement analysis required motion capture and was tested only in mild to moderate impairment.
• PTOTSLPOther2019Outcome measures in post-stroke arm rehabilitation trials: do existing measures capture outcomes that are important to stroke survivors, carers, and clinicians?Clinical rehabilitationStroke survivors prioritized independence and freedom, but the most common trial measures for arm rehabilitation failed to capture these outcomes. Clinicians focused on everyday tasks and pain. Current research tools often miss what matters most to patients.
• OTSLPPilot2019User activity recognition system to improve the performance of environmental control interfaces: a pilot study with patients.Journal of neuroengineering and rehabilitationIn eight patients with neurological or spinal cord conditions, a prediction-assisted environment control interface let them complete more daily tasks in ten minutes than manual scanning. Users did not report lower workload.
• PTOTOther2019A study on the sleep quality, pain, and instrumental activities of daily living of outpatients with chronic stroke.Journal of physical therapy scienceOutpatients with chronic stroke who reported worse sleep and more pain had lower independence in daily tasks like grooming and shopping. These factors correlate with daily function, but the study cannot prove they cause the decline.
• PTOTCohort2019Predictive utility of an adapted Marshall head CT classification scheme after traumatic brain injury.Brain injuryAn adapted Marshall CT classification did not meaningfully predict injury severity or functional outcomes after moderate-severe TBI. It only helped predict whether acute surgery was done, so it should not guide long-term rehabilitation prognosis.
• OTOther2018Friendship Quality, Friendship Quantity, and Social Participation in Adults with Traumatic Brain Injury.Seminars in speech and languageAdults with TBI had less social participation than matched peers, but their friendships were rated as high quality and their number of friends was not clearly lower. Most still had at least one close friendship their friend also valued.
• PTOTOther2019A postural unloading task to assess fast corrective responses in the upper limb following stroke.Journal of neuroengineering and rehabilitationA robotic arm test that removes a background load gave steadier results in healthy people and identified more stroke-related arm control problems than a test that adds a load, especially trouble slowing the arm.
• PTOTSLPCohort2019Use of Hospital-Based Rehabilitation Services and Hospital Readmission Following Ischemic Stroke in the United States.Archives of physical medicine and rehabilitationIn Medicare claims for 88,826 older adults after ischemic stroke, more hospital physical therapy was linked to lower 30-day readmission. Occupational therapy and speech-language therapy showed no such link, so this does not prove these treatments prevent readmission.
• PTOTMeta-Analysis2019Effect of Specific Over Nonspecific VR-Based Rehabilitation on Poststroke Motor Recovery: A Systematic Meta-analysis.Neurorehabilitation and neural repairRehabilitation-specific and commercial VR did not differ clearly. Rehabilitation-specific VR showed better upper-limb movement and daily hand use than usual therapy, while commercial VR did not.
• PTOTNarrative Review2019Tele-monitored tDCS rehabilitation: feasibility, challenges and future perspectives in Parkinson's disease.Journal of neuroengineering and rehabilitationRemote tDCS for Parkinson's is feasible and safe, with high compliance and mild side effects. Efficacy data is pending or limited to small open-label studies, so it should not be used as a proven treatment for motor or cognitive symptoms yet.
• PTOTSLPOther2019Altered muscle activation patterns (AMAP): an analytical tool to compare muscle activity patterns of hemiparetic gait with a normative profile.Journal of neuroengineering and rehabilitationA new muscle activity analysis tool identified specific timing and amplitude deviations in stroke survivors' walking. Plantarflexor abnormalities correlated with reduced propulsion and slower walking speeds, offering a way to target gait rehabilitation based on individual muscle coordination deficits.
• PTOTRCT2019Brain-Machine Interface in Chronic Stroke: Randomized Trial Long-Term Follow-up.Neurorehabilitation and neural repairPatients with severe chronic stroke arm paresis who received contingent brain-machine interface training plus physiotherapy had higher combined hand and arm motor scores six months later than before. Sham training plus physiotherapy did not significantly change scores. BMI was not tested without physiotherapy.
• PTOTCohort2019Estimated Life-Time Savings in the Cost of Ongoing Care Following Specialist Rehabilitation for Severe Traumatic Brain Injury in the United Kingdom.The Journal of head trauma rehabilitationSpecialist inpatient rehabilitation for severe traumatic brain injury was associated with large estimated reductions in ongoing care costs, but this observational cost analysis assumed gains would persist without rehabilitation.
• PTOTOther2018Reliability and validity of transfer assessment instrument version 3.0 in individuals with acute spinal cord injury in early rehabilitation phase.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoThe Transfer Assessment Instrument 3.0 consistently rated wheelchair transfers in early spinal cord injury rehab. Raters agreed closely on scores, and the tool aligned with overall transfer quality judgments. Use it to standardize transfer evaluation and identify techniques risking upper limb injury.
• PTOTSLPCohort2019Pregnancy Outcomes in Women with Spinal Cord Injuries: A Population-Based Study.PM & R : the journal of injury, function, and rehabilitationMothers with spinal cord injury, paralysis, or spina bifida faced high risks of infection, blood clots, and preterm birth. Infants were often born early or small. However, these babies did not have higher rates of hospitalization or death in their first two years compared to other infants.
• PTOTSLPRCT2019Ergometer cycling improves the ambulatory function and cardiovascular fitness of stroke patients-a randomized controlled trial.Journal of physical therapy scienceAdding ergometer cycling to standard physiotherapy improved walking speed, endurance, and blood pressure in sub-acute stroke patients compared to physiotherapy alone. The cycling group walked faster and covered more distance, but the study was small and short.
• PTOTOther2019Actigraph assessment for measuring upper limb activity in unilateral cerebral palsy.Journal of neuroengineering and rehabilitationWrist sensors used during play separated children with unilateral cerebral palsy from typically developing peers, and greater hand difficulty showed greater asymmetry. This supports actigraphy as an objective measure of arm use.
• PTOTCohort2018Stratification of stroke rehabilitation: Five-year profiles of functional outcomes.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoStroke rehab patients admitted who needed help or supervision to walk showed the biggest daily mobility and self-care gains. Those unable to sit, sitting but not walking, or already independent gained less per day. Admission walking level indicated likely discharge mobility.
• PTOTSLPCohort2019Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury: Examining Associations With Demographics, Healthcare Utilization, Institutionalization, and 1-Year Outcomes.The Journal of head trauma rehabilitationOlder adults with TBI and acute hospital complications had longer stays and higher rehospitalization rates. Those with chronic disease burdens also faced higher rehospitalization risks. Substance abuse clusters were linked to institutionalization but not 1-year functional outcomes. These patterns highlight distinct risk profiles for discharge planning.
• OTRCT2019Effect of the Wii Sports Resort on the improvement in attention, processing speed and working memory in moderate stroke.Journal of neuroengineering and rehabilitationModerate stroke patients who also used Wii for 8 weeks did not improve attention, speed or working memory more than those on usual stroke rehabilitation. Usual rehabilitation included walking, physiotherapy, occupational therapy, speech therapy and neuropsychology.
• OTCohort2019Relationship Consensus and Caregiver Burden in Adults with Cognitive Impairments 6 Months Following Stroke.PM & R : the journal of injury, function, and rehabilitationCaregivers of stroke survivors with cognitive impairments who reported less agreement on goals and expectations were more likely to have high burden. Time together and satisfaction did not track with burden in the main analysis.
• OTOther2019Evaluation of tremor interference with control of voluntary reaching movements in patients with Parkinson's disease.Journal of neuroengineering and rehabilitationPeople with Parkinson's disease and tremor began reaching later and took longer to complete movements than controls. Measured tremor intensity tracked the delay in starting, but clinical tremor scores did not.
• PTOTRCT2019Boosting robot-assisted rehabilitation of stroke hemiparesis by individualized selection of upper limb movements - a pilot study.Journal of neuroengineering and rehabilitationThe group comparison of selected versus standard upper-limb movement training before adjusting for baseline scores was not significant. After accounting for baseline scores, the group trained on selected movements had an adjusted change of 4.42 versus 2.12 Fugl-Meyer points, but other outcomes were null.
• PTOTOther2019Self-efficacy and Reach Performance in Individuals With Mild Motor Impairment Due to Stroke.Neurorehabilitation and neural repairConfidence for reaching was lower with the more affected arm in 20 people with mild arm impairment after stroke and 6 controls. Confidence about accuracy tracked accuracy on reaches across the body; speed confidence did not track speed for the more affected arm.
• PTOTSystematic Review2019Effects of Dopamine on Motor Recovery and Training in Adults and Children With Nonprogressive Neurological Injuries: A Systematic Review.Neurorehabilitation and neural repairEvidence for dopamine medication was mixed. Some levodopa stroke studies showed motor improvement, but evidence for traumatic brain injury, cerebral palsy, and spinal cord injury was weak.
• PTOTRCT2019Myoelectric Computer Interface Training for Reducing Co-Activation and Enhancing Arm Movement in Chronic Stroke Survivors: A Randomized Trial.Neurorehabilitation and neural repairChronic stroke survivors using EMG computer arm training improved Fugl-Meyer arm scores by 3.3 points at 6 weeks, with gains at 10 weeks. No dose or movement versus isometric training was clearly better, and there was no control group.
• PTOTCohort2019Relationships between gait variability and ambulatory activity post stroke.Topics in stroke rehabilitationStroke survivors who showed more variable step timing when walking in a busy lobby took fewer daily steps and had shorter walking bouts. This link was absent when they walked in a quiet hallway, suggesting clinic tests may miss real-world activity predictors.
• PTOTMeta-Analysis2019Sensory retraining of the leg after stroke: systematic review and meta-analysis.Clinical rehabilitationInterventions aimed at leg sensory retraining after stroke improved leg sensation and balance in pooled studies, but gait speed did not improve. The evidence came from small, low-quality trials, so it is not enough to change routine care by itself.
• OTCohort2019Depressive symptoms in caregivers immediately after stroke.Topics in stroke rehabilitationDepressive symptoms stayed similar from 2 to 6 weeks, but 57% of caregivers had at least mild symptoms early. Uncertainty, stress, coping, support, income, and stroke-survivor function were linked to symptoms; cortisol was not.
• PTOTRCT2019A suite of automated tools to quantify hand and wrist motor function after cervical spinal cord injury.Journal of neuroengineering and rehabilitationA new set of hand and wrist measurement tools reliably quantified muscle force deficits in people with cervical spinal cord injury, matching scores from standard clinical exams. The tools distinguish impaired strength from preserved movement range, offering a precise way to track recovery over time.
• PTOTSLPCohort2019The Effect of Frailty on Discharge Location for Medicare Beneficiaries After Acute Stroke.Archives of physical medicine and rehabilitationFrail Medicare patients were less likely to go to inpatient rehab than non-frail patients with similar stroke severity. They were instead sent to skilled nursing facilities or home. This suggests pre-stroke frailty, not just stroke severity, drives discharge location.
• PTOTRCT2019Dynamic Lycra® orthoses as an adjunct to arm rehabilitation after stroke: a single-blind, two-arm parallel group, randomized controlled feasibility trial.Clinical rehabilitationNo clear benefit was seen when adding dynamic Lycra orthoses to usual arm rehabilitation after stroke. The usual-care group showed more improvement on several arm outcomes, and wear was linked to skin, swelling and discomfort problems.
• OTRCT2019Clinical and cost effectiveness of memory rehabilitation following traumatic brain injury: a pragmatic cluster randomized controlled trial.Clinical rehabilitationGroup memory rehabilitation plus usual care did not produce a clinically important improvement in self-reported everyday memory compared with usual care alone at the main follow-up. Some objective and goal attainment outcomes favoured it, but the primary patient-reported memory result was not positive.