Neurosensory Screening and Symptom Provocation in Pediatric Mild Traumatic Brain Injury.
Andrew R Mayer, Christopher J Wertz, Cidney R Robertson-Benta and 18 others
PMID 32108710WHAT IT FOUND
Children about one week after mild head injury had higher symptom ratings and more symptom increase during neurosensory tests than healthy peers.
But test scores did not reliably identify individual injured children; they improved prediction of persistent symptoms at four months.
Key findings
01The primary symptom outcomes showed group differences: patients had higher pre-test symptom ratings and higher total symptom provocation than controls.
02Adding total symptom provocation to pre-test symptoms did not meaningfully improve classification of individual patients versus controls.
03Clinically relevant symptom provocation at one week improved prediction of persistent symptoms at four months, mainly by identifying more patients with persistent symptoms.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTs
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What it does not show
The sample was too small to detect smaller effects or examine whether non-specific symptom provocation predicted long-term outcomes. Test administrators were not blinded to whether participants were patients or controls. Many children had zero scores: 46 of 146 patients and 72 of 104 controls had zero pre-test symptoms, and 62 of 146 patients and 75 of 104 controls had zero symptom provocation. These zero scores limit how accurately any test can classify individuals. The study was done in emergency department and urgent care settings, and point of care may influence deficits detected. The clinical risk score used for comparison was developed from more acute assessments than those used here. Symptom provocation was calculated as change from pre-test ratings, and results may vary if calculated differently. The four-month analyses included fewer participants than the baseline sample; at the time of investigation, 125 of 146 patients and 89 of 104 controls were eligible for follow-up, and 105 of 146 patients and 83 of 104 controls completed.
Declared interests
No author conflicts of interest are reported in the supplied text. The article is supported by the National Institutes of Health, Extramural.
The easy way to misread this
Do not read the group differences as proof that this exam diagnoses an individual child or predicts poor recovery. Total symptom provocation did not meaningfully improve single-subject classification, and it did not improve prediction of quality of life.