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Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 1 OF 56 · NEWEST FIRST

• PTOTSLPRNQualitative2017Preferences and concerns for care needs in advanced Parkinson's disease: a qualitative study of couples.Journal of clinical nursingCouples with advanced Parkinson's disease described frequent falls, speech and swallowing problems, financial strain and lack of prognostic information as major concerns. They wanted to stay home but often had no plans because they did not know what to expect.
• PTOTRNQualitative2017Life after stroke in Appalachia.International journal of nursing sciencesRural stroke survivors described recovery as adjusting to a new body, emotions, and dependence. Anger, guilt, loneliness, and transport barriers shaped post-discharge life. Mood and access need assessment alongside function.
• PTOTRNMeta-Analysis2017The effect of Tai Chi exercise on motor function and sleep quality in patients with stroke: A meta-analysis.International journal of nursing sciencesTai Chi added to usual care improved balance and daily activities in stroke patients, but did not improve walking speed or sleep quality. The evidence is weak due to high variability between studies and short follow-up, so it should not replace standard rehab.
• PTOTSLPRNCohort2017Quality of life of patients using intermittent urinary catheterization.Revista latino-americana de enfermagemQuality of life scores were similar in Brazil and Portugal, but Brazilian patients rated their general health higher. Patients who self-catheterized reported better physical and psychological well-being than those needing caregiver help.
• PTOTSLPRNSurvey2017Self-Reported Symptoms of Parkinson's Disease by Sex and Disease Duration.Western journal of nursing researchMen reported more non-motor symptoms than women. Motor symptoms increased with disease duration, but non-motor symptoms did not. Speech problems peaked in the 6-to-10-year group, while hallucinations appeared most often after 10 years.
• PTOTSLPRNSurvey2017Beliefs About Use of Complementary Health Approaches for Parkinson's Disease.Holistic nursing practicePeople with Parkinson's disease using complementary health approaches believed these methods were effective for symptom control and necessary for general health. They reported low concern about side effects or drug interactions but expressed willingness to disclose their use to healthcare professionals.
• OTPilot2018Microclimate evaluation of strap-based wheelchair seating systems for persons with spinal cord injury: A pilot study.Journal of tissue viabilityStrap-based wheelchair seats for Veterans with spinal cord injury did not differ from usual seats at the skin-seat interface, but thermal images showed solid strap seats cooled faster after use.
• PTOTSLPRNCohort2018The Initiation of Rehabilitation Therapies and Observed Outcomes in Pediatric Traumatic Brain Injury.Rehabilitation nursing : the official journal of the Association of Rehabilitation NursesChildren with traumatic brain injury received rehabilitation services at different times by injury severity, and most had no delay on a speech pathology evaluation at follow-up. The study did not show that earlier or more frequent therapy improved recovery.
• PTOTRNCohort2018Examining age-related differences in functional domain impairment following traumatic brain injury.International journal of older people nursingOlder adults after mild-moderate traumatic brain injury had worse mobility, travel, home maintenance and overall function for a year. Better pre-injury physical health was linked to better function; better pre-injury mental health was sometimes linked to worse function in older adults.
• PTOTRNPilot2019Exploring the Adaptability of Tai Chi to Stroke Rehabilitation.Rehabilitation nursing : the official journal of the Association of Rehabilitation NursesCommunity stroke survivors in a 12-month adapted group program attended 72% of classes, had no intervention-related falls or adverse events, and reported better balance, flexibility, and confidence. The program included many components, so the contribution of any single component cannot be separated.
• PTOTRNNarrative Review2019Review of Treatment for Central Spinal Neuropathic Pain and Its Effect on Quality of Life: Implications for Neuromyelitis Optica Spectrum Disorder.Pain management nursing : official journal of the American Society of Pain Management NursesTreating central spinal neuropathic pain often reduces pain but fails to improve quality of life. Across 21 studies, only six improved both. Clinicians should target symptom clusters like fatigue and mood, not just pain intensity, to help patients feel better.
• OTSLPQualitative2020Recalibrating hope: A longitudinal study of the experiences of people with aphasia after stroke.Scandinavian journal of caring sciencesFour people with aphasia kept broad hope while revising specific hopes over the year after stroke. Hope depended on perceived progress, meaningful roles, and social connection.
• OTRNSurvey2019Functional and self-care capacity of people with multiple sclerosis.Revista latino-americana de enfermagemMost outpatients with MS had self-care capacity (82.1%), but 51.2% were moderately dependent for basic tasks. Higher disability and older age were linked to greater dependence.
• OTRNSurvey2019Predicting the functional independence during the recovery phase for poststroke patients.Nursing openThe largest group of stroke survivors reported low confidence in their functional independence. Confidence differed by age, rural versus urban living, recurrent stroke, and knowing their diagnosis.
• PTOTRNQualitative2019Caring for a stroke patient: The burden and experiences of primary caregivers in Uganda - A qualitative study.Nursing openUgandan stroke caregivers described sudden duties, financial strain and exhaustion. Recovery brought relief; death brought grief. They valued listening and support from staff and family, but lacked supplies, rehabilitation and follow-up.
• PTOTRNPilot2019Family-Centered Care During Constraint-Induced Therapy After Chronic Stroke: A Feasibility Study.Rehabilitation nursing : the official journal of the Association of Rehabilitation NursesA carepartner program given with constraint-induced therapy after stroke was feasible: all seven survivors completed 10 sessions, with no adverse events. Descriptive caregiver and survivor gains occurred, but the small single-group study cannot separate the program from therapy.
• PTOTSLPRNCohort2020Effect of Age on Longitudinal Changes in Symptoms, Function, and Outcome in the First Year After Mild-Moderate Traumatic Brain Injury.The Journal of neuroscience nursing : journal of the American Association of Neuroscience NursesOlder adults with mild-moderate brain injury report more balance and coordination problems and worse physical health than younger adults in the first year. They also have higher risk of repeat falls. Screen for these specific issues and refer to balance programs.
• PTOTRNRCT2020Visual feedback therapy for restoration of upper limb function of stroke patients.International journal of nursing sciencesStroke patients who added visual feedback therapy to conventional stroke care and rehabilitation had better upper limb movement and daily independence after 8 weeks, and the advantage remained at 2 months in the 17 followed patients.
• PTOTRNRCT2020Effect of Delirium on Physical Function in Noncardiac Thoracic Surgery Patients.American journal of critical care : an official publication, American Association of Critical-Care NursesDelirium after major noncardiac thoracic surgery did not significantly change muscle strength scores. Patients with delirium had lower self-reported independence at discharge, but this was a secondary outcome in a small analysis.
• PTOTPilot2020Yoga improves balance, mobility, and perceived occupational performance in adults with chronic brain injury: A preliminary investigation.Complementary therapies in clinical practiceEight weeks of group yoga, including physical postures, breath work, affirmations, and meditation/relaxation, was associated with improved balance, walking distance, and perceived occupational performance in seven adults with chronic brain injury; balance confidence, pain, and performance satisfaction did not change.
• OTCohort2020Development and Validation of a Nomogram for Predicting the 6-Year Risk of Cognitive Impairment Among Chinese Older Adults.Journal of the American Medical Directors AssociationA simple chart using age, daily function, MMSE, stroke, chewing, vision, TV/radio, and pets estimated six-year cognitive impairment risk in Chinese adults aged 65 and above without baseline impairment and matched observed risk in a second cohort.
• OTQualitative2021Pain and Symptoms after Mild Traumatic Brain Injury: Should Technology Play a Role in Self-Management?Pain management nursing : official journal of the American Society of Pain Management NursesSeven young women recovering from mild brain injury said they lacked clear guidance on managing pain, memory and concentration problems. They wanted a phone app to track symptoms and treatments and share selected information with clinicians, coaches, teachers or family.
• PTOTRNCohort2021Predictors and short-term outcomes of post-stroke fatigue in initial phase of transition from hospital to home: A prospective observational study.Journal of advanced nursingFatigue in the acute phase, within 2 weeks of admission, predicted fatigue one month after discharge. Persistent fatigue was associated with depression, insomnia, sarcopenia risk, and lower quality of life, but this study did not test treatment.
• PTOTQualitative2021Stroke survivors' experiences with rebuilding life in the community and exercising at home: A qualitative study.Nursing openSome stroke survivors built exercise into valued daily routines, such as walking in a shopping mall or climbing steps at home. They said fear of falling, low motivation and little professional feedback made home exercise hard.
• OTRNQualitative2022Experiences of quality of life in people with Multiple Sclerosis who are in a wheelchair.Nursing openSix wheelchair users with MS living at home said quality of life depended on managing everyday life and being seen as themselves. Hope, aids and talking about limits helped; fatigue and people addressing family members instead threatened identity.
• PTOTSLPRNSystematic Review2022A systematic review of the qualitative literature on older individuals' experiences of care and well-being during physical rehabilitation for acquired brain injury.Journal of advanced nursingOlder adults after brain injury described wanting more frequent physiotherapy, family involvement, respectful communication, and choices in discharge. Creative activities and feeling autonomous were linked with well-being. These are experiences, not proof of effect.
• PTOTCohort2021Functional Status Across Post-Acute Settings is Associated With 30-Day and 90-Day Hospital Readmissions.Journal of the American Medical Directors AssociationPatients with lower self-care or mobility function at the initial post-acute stay had higher 30-day and 90-day readmission risk across stroke, lower extremity joint replacement and hip/femur fracture/procedure. Function flags risk; it does not prove rehabilitation prevents readmission.
• OTRNSurvey2022The influence of the disclosure of diabetes on the cognitive, physical ability and diabetes self-management in diabetic employed adults in Saudi Arabia.Nursing openEmployed Saudi adults with diabetes who told their manager had worse fatigue, concentration, motivation and activity scores. Self-management confidence was lower with higher fatigue and poorer concentration, but the study cannot show disclosure caused this.
• OTRNRCT2022Stroke Family Caregiver Life Changes From the COVID-19 Pandemic.The Journal of neuroscience nursing : journal of the American Association of Neuroscience NursesStroke caregivers reported disrupted routines and reduced social contact, but also increased use of videoconferencing and internet ordering. Financial well-being and physical health changed little on average. Individual responses varied widely, requiring personalized support rather than a one-size-fits-all approach.
• PTOTOther2022Characterizing Standardized Functional Data at Inpatient Rehabilitation Facilities.Journal of the American Medical Directors AssociationInpatient rehab records show Section GG and FIM mostly line up, but Section GG often scores patients as more independent. Transfer change scores were least consistent. Higher Section GG scores can mean device use or different definitions, not better function.
• OTRNPilot2022Piloting GETCare: A Goal-Based Education and Skills Training Program for Caregivers.Rehabilitation nursing : the official journal of the Association of Rehabilitation NursesOnly 18 of 28 caregivers completed this 5-week remote stroke caregiver program, for 64% completion against a 75% retention target. Among those completing at least 4 modules, all were at least quite satisfied, and 78% found the booklet at least quite helpful.
• PTOTQualitative2023Actual experience of the training effect of Baduanjin on patients with hemiplegic limb dysfunctions after cerebral infarction: A qualitative study.Nursing openAfter Baduanjin training, patients with one-sided weakness after stroke said their limbs felt stronger, steadier and more usable, and tasks like stairs, standing and holding a cup became easier. They also said the exercises felt hard at first, then manageable.
• OTRNQualitative2022Stroke Survivors and Their Family Caregivers' Experiences of Health Information Seeking: A Qualitative Study.International journal of community based nursing and midwiferyStroke survivors and caregivers said finding information helped them learn home care and adapt the house, but conflicting advice and unclear post-discharge support left them anxious about recovery.
• PTOTSLPOther2022Social withdrawal in Parkinson's disease: A scoping review.Geriatric nursing (New York, N.Y.)Parkinson's social withdrawal is linked to motor symptoms, speech difficulty, anxiety, depression, stigma and cognitive change. Some community activity and self-management programs were reported to improve participation, but the review did not prove cause.
• OTPilot2022Return to Learn ECHO: Telementoring for School Personnel to Help Children Return to School and Learning After Mild Traumatic Brain Injury.The Journal of school healthSchool personnel who took a short virtual concussion-return-to-learn program reported greater confidence about managing return to learn and communicating with families. This is staff self-report only, not proof that students improved.
• PTOTSLPRNCohort2023Comprehensive Geriatric Hospital at Home: Adaptation to Referral and Case-Mix Changes During the COVID-19 Pandemic.Journal of the American Medical Directors AssociationHospital-at-home services for older adults adapted to pandemic changes without worsening outcomes. However, patients referred directly from the community achieved less functional recovery than those stepping down from hospital. Community referrals often involved more complex, frail patients.
• PTOTRNQualitative2023Medical staff's perception of factors contributing to accelerated rehabilitation in patients with cervical spinal cord injury: A qualitative research.Nursing openStaff cited inconsistent messaging and heavy workloads as barriers to Enhanced Recovery After Surgery in cervical spinal cord injury. Nurses reported delaying catheter removal on night shifts due to staffing shortages. Patients' belief that rest aids healing reduced compliance with early mobilization.
• PTOTSLPRNCohort2023Pain and Associated Factors in Nursing Home Residents.Pain management nursing : official journal of the American Society of Pain Management NursesNursing home residents with intact cognition, arthritis, depression, anxiety, or contractures were more likely to report severe or persistent pain. Residents with Alzheimer’s disease reported less pain, likely due to assessment difficulties rather than lower pain levels.
• PTOTCohort2023Post-Acute Care in Inpatient Rehabilitation Facilities Between Traditional Medicare and Medicare Advantage Plans Before and During the COVID-19 Pandemic.Journal of the American Medical Directors AssociationDuring the pandemic, inpatient rehabilitation stays became shorter and more expensive, with far more patients discharged home with home health care and fewer to nursing facilities. Differences between traditional and managed care plans narrowed, but the study shows association, not cause.
• PTOTSLPRNCohort2023Trajectories of Functional Decline in Older Adults: A Latent Class Growth Curve Analysis.Western journal of nursing researchMost older adults stay independent until age 85, but 10% decline rapidly from age 65 and 11% start with high disability. Comorbidities drive decline more than race or sex. Identify these groups early to target care.
• PTOTSLPRNCohortLongitudinal Effects of Sex, Aging, and Multiple Sclerosis Diagnosis on Function.Nursing researchMen with MS experienced faster functional decline over time. Women showed greater year-to-year variability in function. Older adults had higher baseline limitation and more diverse trajectories. Sex and age shape how MS progresses differently.
• PTOTSLPRNOther2023King's Parkinson's Disease Pain Questionnaire: reliability and convergent construct validity.Revista brasileira de enfermagemThe King's Parkinson's Disease Pain Questionnaire is reliable for assessing pain in Brazilian older adults with Parkinson's. A change of 9 points on its 168-point scale marks a clinically important difference. It correlates weakly with general pain measures, suggesting it captures Parkinson-specific pain.
• PTOTSLPRNNarrative Review2023Multidimensional Frailty and Traumatic Brain Injury among Older Adults: A Literature Review.Investigacion y educacion en enfermeriaFrailty predicts worse outcomes after traumatic brain injury in older adults, including higher rates of emotional distress, venous thromboembolism, and functional decline. A multidimensional assessment of physical, psychological, and social frailty may help clinicians anticipate recovery trajectories.
• OTPilot2023The BETTER Traumatic Brain Injury Transitional Care Intervention: A Feasibility Study.Western journal of nursing researchOccupational therapists delivering a transitional care program to TBI patients and families found it feasible and acceptable. Physical quality of life improved, but overall and mental quality of life did not change. These results support testing the program in a larger randomized trial.
• PTOTRNSurvey2023Stroke severity to determine musculoskeletal symptoms in family caregivers.Revista latino-americana de enfermagemFamily caregivers of stroke survivors reported low back pain most often, and their low back and shoulder symptoms were linked to the patient's disability. Neck, hip, knee and foot pain did not track the patient's condition.
• PTOTSLPRNRCT2023Effectiveness of a family-based program for post-stroke patients and families: A cluster randomized controlled trial.International journal of nursing sciencesIn Thai stroke families, a 10-week family program improved patient function and family functioning, and lowered patient depression at 12 weeks, but caregiver burden did not differ between groups.
• PTOTSLPRNCohort2024The meaning of health to persons aging with longstanding multiple sclerosis.Research in nursing & healthPeople aging with MS valued health as function and adaptation more than absence of disease. Over 26 years, agreement with both definitions declined slightly, but self-rated health remained largely stable. Wellness-focused views linked to more health behaviors.
• PTOTRNOther2025Interventions facilitating the involvement of relatives of patients with acquired brain injury or malignant brain tumour: A scoping review.Journal of clinical nursingRelatives of stroke and brain tumour patients were involved in many varied interventions, commonly including education and physical activity or training, often delivered by nurses. Outcomes and involvement were not measured consistently, so it cannot show which approach works.
• OTQualitative2025Navigating Life With Parkinson's Disease: A Focus Group Study on Coping Strategies and Considerations for Self-Management Support.Journal of advanced nursingPeople with Parkinson's disease described coping as changing over time, often moving from denial or avoidance to proactive task-oriented strategies after a key point. They wanted tailored self-management support beyond medication, including peers, lifestyle, psycho-emotional guidance and autonomy.
• PTOTQualitative2025Nurses' Descriptions of Interdisciplinary Interactions in Stroke and Geriatric Rehabilitation Units: A Case Example of the Registered Practical Nurse.Journal of advanced nursingThirty-one Ontario registered practical nurses said rehab team interactions depended on clear roles and communication: they carried over therapy, followed therapist transfer and swallowing directives, and used whiteboards/charts. These are perceptions, not patient outcomes.