TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 26 OF 56 · NEWEST FIRST

• PTOTCohort2022A Prediction Model for Various Treatment Pathways of Upper Extremity in Tetraplegia.Frontiers in rehabilitation sciencesMotor point mapping and ASIA scores taken 4 to 8 weeks after cervical spinal cord injury predict hand muscle strength at 6 months. Intact lower motor neurons and AIS C or D scores strongly indicate that patients will develop useful voluntary movement.
• PTOTSLPPilot2022Operant down-conditioning of the soleus H-reflex in people after stroke.Frontiers in rehabilitation sciencesHalf of stroke survivors successfully reduced a spinal reflex through training. Those who succeeded walked faster by 0.14 m/s on average. The other half did not improve reflex size, but their walking speed did not worsen either.
• PTOTSLPCohort2022The Interrelationship of Tinnitus and Hearing Loss Secondary to Age, Noise Exposure, and Traumatic Brain Injury.Ear and hearingHearing loss is the strongest risk factor for tinnitus, increasing risk 4.15 times. Tinnitus often precedes measurable hearing loss, suggesting it may be an early warning sign. Veterans over 40 with tinnitus have an 80% likelihood of developing hearing difficulties.
• PTOTCase Series2022Feasibility and Acceptability of Game-Based Cortical Priming and Functional Lower Limb Training in a Remotely Supervised Home Setting for Chronic Stroke: A Case Series.Frontiers in rehabilitation sciencesThree chronic stroke survivors completed 24 home sessions of game-based ankle priming and lower limb training remotely. All showed walking speed gains meeting the minimal clinically important difference. The program was feasible and safe, but without a control group, efficacy remains unproven.
• PTOTSLPQualitative2022Facilitators and Barriers to Sustainable Employment After Spinal Cord Injury or Acquired Brain Injury: The Person's Perspective.Frontiers in rehabilitation sciencesPeople with spinal cord or acquired brain injury described sustainable work as depending on accessible, flexible workplaces, supportive colleagues, and confidence to explain their needs. Insurance delays and invisible fatigue were major barriers.
• PTOTSurvey2022Exploring problems for school reintegration following spinal cord injury: Perspectives on the kindergarten through fifth-grade population.Frontiers in rehabilitation sciencesChildren with spinal cord injury often return to school needing new support plans. Physical therapy was the most common need, followed by occupational therapy and counseling. Access barriers remain frequent, and many parents did not know their child's injury level.
• PTOTCase Report2022Improvement in lower extremity hemiplegia in a post-operative brain tumor patient by applying an integrated volitional control electrical stimulator.Journal of physical therapy scienceA man with post-surgical leg paralysis walked faster after IVES gait training, improving from 10.9 to 9.43 seconds over 10 meters. Balance and muscle control also changed, but this single case cannot prove the device works for others.
• PTOTQualitative2022Empowerment, Communication, and Navigating Care: The Experience of Persons With Spinal Cord Injury From Acute Hospitalization to Inpatient Rehabilitation.Frontiers in rehabilitation sciencesPatients with spinal cord injury reported needing to advocate aggressively for their own care and education. They found hospital staff often lacked empathy or specialized knowledge, leaving them unprepared for discharge and forcing them to rely on family and peers to navigate community resources.
• PTOTOther2022Effect of Haptic Training During Manual Wheelchair Propulsion on Shoulder Joint Reaction Moments.Frontiers in rehabilitation sciencesHaptic training raised pushrim force effectiveness but also increased shoulder joint loads. The absolute rise was small, under 10% of maximum effort. Short-term use appears safe, but long-term injury risk remains unknown.
• PTOTCase Series2022Brachial plexus birth injury and cerebral palsy lead to a common contracture phenotype characterized by reduced functional muscle length and strength.Frontiers in rehabilitation sciencesIn ten children with cerebral palsy or brachial plexus injury, affected elbows showed weak muscles that were also functionally short. This suggests contractures stem from impaired muscle growth rather than excess strength, pointing toward lengthening treatments.
• PTOTQualitative2022A focus group study of therapists' views on using a novel neuroanimation virtual reality game to deliver intensive upper-limb rehabilitation early after stroke.Archives of physiotherapyTherapists found virtual reality games engaging but felt their own active presence was essential for success. They warned that without dedicated time, training, and technical support, such intensive therapy is difficult to sustain in routine practice.
• PTOTSystematic Review2022A Scoping Review on Shoulder Injuries of Wheelchair Tennis Players: Potential Risk-Factors and Musculoskeletal Adaptations.Frontiers in rehabilitation sciencesWheelchair tennis players face shoulder risks from overhead motion and muscle imbalances, but evidence is scarce. Most studies included few participants and used different outcome measures, so specific risk factors remain proposed rather than proven.
• PTOTCohort2022Clinical and socio-demographic determinants of community reintegration in people with spinal cord injury in eThekwini Municipality, KwaZulu-Natal province.The South African journal of physiotherapyCommunity reintegration was lower in women and those with muscle spasms. Employment and salary were linked to higher scores, but injury severity and other complications like pressure sores or infections showed no significant association with reintegration levels.
• PTOTQualitative2022Moving goals. Goal-work in Parkinson's disease rehabilitation.Frontiers in rehabilitation sciencesGoal-setting in Parkinson's rehabilitation is a fluid, shared process that continues at home and in clinics. Spouses often co-work on goals, but patients frequently miss that reviews happen because they are un-scheduled and individual. Teams need to make goal-tracking visible to avoid confusion.
• PTOTSLPSurvey2022An evaluation of the structure and process of stroke rehabilitation in primary, secondary and tertiary hospitals in Ghana.The South African journal of physiotherapyIn Ghana, stroke care varies sharply by hospital level. Tertiary hospitals offer five sessions weekly with full teams and imaging, while primary and secondary sites provide only two weekly sessions, lack specialists like speech therapists, and have no on-site scans. Protocols are often inaccessible to staff.
• PTOTPilot2022A Remotely Delivered Progressive Walking Intervention for Adults With Persistent Symptoms of a Mild Traumatic Brain Injury: Feasibility and Exploration of Its Impact.Frontiers in rehabilitation sciencesFor adults with persistent concussion symptoms, a remote progressive walking programme with coaching, monitoring and education was feasible, safe and well accepted. Participants walked more and reported fewer symptoms, less fear of movement, less fatigue and better quality of life.
• PTOTOther2022Enhancing touch sensibility by sensory retraining in a sensory discrimination task via haptic rendering.Frontiers in rehabilitation sciencesHealthy adults improved their ability to distinguish virtual textures after training with a robotic device. The robot guiding the hand was more consistent than letting people explore freely. People felt more competent when the robot guided them. This is a test in healthy adults, not patients.
• PTOTSLPOther2022Development and Validation of the Short-LIMOS for the Acute Stroke Unit-A Short Version of the Lucerne ICF-Based Multidisciplinary Observation Scale.Frontiers in rehabilitation sciencesA 10-item stroke-unit observation scale rated motor, cognitive and communication daily tasks consistently, closely matched the original 45-item LIMOS, and tracked the Barthel Index moderately.
• PTOTOther2022Biomechanical assessment of the ipsilesional upper limb in post-stroke patients during multi-joint reaching tasks: A quantitative study.Frontiers in rehabilitation sciencesStroke patients show measurable movement deficits in their 'unaffected' arm. These deficits are worse in patients with severe weakness on the other side and do not fully resolve by the subacute stage. Clinicians should assess and treat the non-paralyzed arm.
• PTOTRCT2022Effect of a tailored upper extremity strength training intervention combined with direct current stimulation in chronic stroke survivors: A Randomized Controlled Trial.Frontiers in rehabilitation sciencesTailoring strength training intensity to individual brain excitability markers improved arm function and grip in chronic stroke survivors. Adding anodal tDCS provided no further benefit. The training gains occurred regardless of whether participants received real or sham stimulation.
• PTOTSLPQualitative2022Hope for "Continued Vitality": Qualitative Study of Adults With Traumatic Brain Injury and Low Mood on Their Rehabilitation.Frontiers in rehabilitation sciencesAdults with concussion and low mood described feeling invalidated when providers doubted their invisible symptoms, worsening their distress. They wanted providers to believe them, set realistic recovery expectations, and coordinate care so they did not have to self-advocate.
• PTOTOther2022Effect of Fatiguing Wheelchair Propulsion and Weight Relief Lifts on Subacromial Space in Wheelchair Users.Frontiers in rehabilitation sciencesWheelchair users with spinal cord injury had a narrowed subacromial space during weight relief lifts, especially those with low anaerobic capacity. However, fatiguing wheelchair propulsion did not change the space or tendon compression ratios, suggesting daily propulsion alone does not cause immediate narrowing.
• PTOTQualitative2022How do people with physical/mobility disabilities benefit from a telehealth exercise program? A qualitative analysis.Frontiers in rehabilitation sciencesParticipants with disabilities described the telehealth exercise program as helping them feel stronger, more mobile, and happier. They valued the routine and accountability but requested more options to adjust exercise speed and difficulty to match their changing abilities.
• PTOTSLPOther2022Body Mass Index and Exercise Effort Influences Changes in Motor Symptoms After High-Cadence Dynamic Cycling in Parkinson's Disease.Frontiers in rehabilitation sciencesHigh-cadence cycling improved Parkinson's motor symptoms in this pooled analysis, but baseline severity predicted the outcome. Effort alone did not explain the variance; instead, higher BMI weakened the link between effort and symptom improvement.
• PTOTOther2022Lower Kinetic Chain, Meet the Thinking Brain: A Scoping Review of Cognitive Function and Lower Extremity Injury Risk.International journal of sports physical therapyAdding cognitive demands to physical tasks consistently worsened lower-limb mechanics, such as reducing knee flexion and increasing valgus. Athletes with a history of concussion showed higher rates of subsequent lower-limb injury, even after symptoms resolved.
• PTOTQualitative2022Health care professionals' experiences with goal setting during initial rehabilitation after newly acquired spinal cord injury/ disorder - a qualitative focus group study.Frontiers in rehabilitation sciencesHealth care professionals described goal setting after spinal cord injury as shaped by insurance limits, team meetings, and patient emotions. Interprofessional goal rounds helped include patients, while small achievable steps eased tension from unrealistic hopes and uncertainty.
• OTRCT2022Effects of Combining Cognitive Behavioral Therapy with Bilateral Upper Limb Training in Stroke Patients: A Randomized Controlled Trial.Occupational therapy internationalAdding cognitive behavioral therapy to bilateral upper limb training reduced depression, anxiety, and negative thoughts in stroke patients. It did not improve upper limb function more than conventional therapy, but it did increase patient satisfaction with their performance.
• PTOTCase Report2022Case Report: Galvanic Vestibular Stimulation in the Chronic Spinal Cord Injury Patient.Frontiers in rehabilitation sciencesOne patient with chronic tetraplegia improved in sitting balance and self-care after ten sessions combining noise galvanic vestibular stimulation, vestibular exercises, and neurofunctional physical therapy. Because several treatments were given together, the contribution of the electrical stimulation alone cannot be separated.
• PTOTSLPCohort2022Changes in social participation between 1 and 2 years following moderate-severe traumatic brain injury.Frontiers in rehabilitation sciencesMost people with moderate-to-severe brain injury showed stable social participation between 1 and 2 years post-injury. Decline was linked to worsening functional status, while improvement was associated with having private insurance and lower baseline social participation.
• PTOTSLPSurvey2022Key demographics and psychological skills associated with adjustment to progressive Multiple Sclerosis early in the diagnosis.Frontiers in rehabilitation sciencesPeople with secondary progressive MS reported worse adjustment than those with primary progressive MS. Self-efficacy, avoidance coping, and psychological vulnerability were the strongest factors linked to how well patients adapted. These findings suggest targeting these specific areas in early rehabilitation support.
• PTOTSLPCohort2023Predictors of cognitive gains during inpatient rehabilitation for older adults with traumatic brain injury.PM & R : the journal of injury, function, and rehabilitationOlder adults with TBI made clinically meaningful cognitive gains in inpatient rehab. Younger age, female sex, higher motor function, longer stays, and freestanding facilities predicted better recovery. Black and Hispanic patients had lower odds of favorable outcomes.
• PTOTSystematic Review2022The use of wearable sensors to assess and treat the upper extremity after stroke: a scoping review.Disability and rehabilitationWearable sensors can track upper extremity motion after stroke, but the review found no evidence that they improve recovery. They map arm use, impairment, and training cues; clinical benefit still needs testing.
• PTOTCohort2022The association between sleep deficits and sedentary behavior in people with mild Parkinson disease.Disability and rehabilitationPeople with mild Parkinson disease slept less and were more sedentary than healthy adults. More sleep linked to less sitting time in both groups. But sleep did not predict step count or active minutes. Treat sitting and moving as separate issues when addressing sleep.
• PTOTSLPCohort2022Exploring Vestibular Ocular Motor Screening in Adults With Persistent Complaints After Mild Traumatic Brain Injury.The Journal of head trauma rehabilitationAdults with persistent mild TBI symptoms showed worse vestibular screening scores and poorer balance/gait than controls. However, these screening scores correlated strongly with self-reported dizziness but weakly with actual physical performance, suggesting they measure different things.
• PTOTSLPSystematic Review2023Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies.Disability and rehabilitationPeople with MS described diagnosis as a period of shock, fear, and anger, often worsened by impersonal communication and unbelieved symptoms. They needed clear, timely information and ongoing emotional support from clinicians, but many felt these needs were unmet.
• PTOTCohort2023The minimal clinically important difference of the motricity index score.Topics in stroke rehabilitationIn 69 patients assessed early after stroke, a 13-point rise on the 0-99 Motricity Index arm score was the cutoff for meaningful recovery compared with another upper-limb test.
• PTOTOther2022Physical Activity and Sedentary Behavior Timing in Fatigued and Nonfatigued Adults With Multiple Sclerosis.Archives of physical medicine and rehabilitationAdults with MS and fatigue took fewer steps and spent less time in moderate-to-vigorous activity than non-fatigued adults. Both groups were most active in the morning and midday, and most sedentary in the evening. Fatigued adults maintained activity longer into the day.
• PTOTCohort2022The demographic and disability characteristics of individuals who regularly attend an urban adaptive fitness center: An observational study.PM & R : the journal of injury, function, and rehabilitationPeople with significant disabilities who attend an adaptive fitness center are more disabled than 86% of the general population. Despite this, 96.8% exercise there at least twice a week, showing that high disability levels do not stop regular participation.
• PTOTRCT2022Music Upper Limb Therapy-Integrated Provides a Feasible Enriched Environment and Reduces Post-stroke Depression: A Pilot Randomized Controlled Trial.American journal of physical medicine & rehabilitationGroup music therapy reduced depression and increased brain-derived neurotrophic factor compared to home exercises. However, home exercises improved actual motor function and sensation, while music therapy only improved self-perceived recovery. Neither was superior on the primary motor outcome.
• OTRCT2022Evaluating occupational performance coaching to support fatigue management for people with multiple sclerosis: A feasibility study.Clinical rehabilitationAdding occupational therapy coaching to a fatigue website helped people with severe multiple sclerosis fatigue set goals and use the site more. While participants felt more confident and less impacted by fatigue, these improvements were not significant enough to prove the coaching works.
• PTOTCohort2022African Americans and Women Have Lower Functional Gains During Acute Inpatient Rehabilitation After Hemorrhagic Stroke.American journal of physical medicine & rehabilitationFemale and African American patients with hemorrhagic stroke made smaller functional gains during acute inpatient rehabilitation than male and white patients. These differences persisted even after accounting for stroke severity, age, and location, pointing to unmeasured factors rather than clinical presentation.
• PTOTSLPCohort2023Intra- and interpersonal effects of coping style and self-efficacy on anxiety, depression and life satisfaction in patient-partner couples after stroke.Neuropsychological rehabilitationProactive coping and self-efficacy in stroke patients and their partners predicted lower anxiety and depression in both individuals over the first year. Intrapersonal effects were stronger, but a patient's coping style also reduced their partner's anxiety, supporting early screening of the couple rather than just the patient.
• OTOther2023Person-centered goal setting is feasible in people with Parkinson's disease who have subjective cognitive decline: a mixed methods study.Disability and rehabilitationPerson-centered goal setting was feasible: 30 people with Parkinson's disease and subjective cognitive decline set 166 goals, averaging 5.53 each, and 144 goals were rated seven or higher importance.
• PTOTSLPCohort2023Using Machine Learning to Examine Suicidal Ideation After Traumatic Brain Injury: A Traumatic Brain Injury Model Systems National Database Study.American journal of physical medicine & rehabilitationA machine learning model predicted suicidal ideation one year after TBI with excellent accuracy. Depressed mood and guilt were the strongest predictors, followed by anhedonia and concentration difficulties. Demographic and injury severity factors added no predictive value. This suggests screening for specific depression symptoms may be more useful than general risk factors.
• PTOTCohort2022Sex and Racial/Ethnic Differences in Within-Stay Readmissions During Inpatient Rehabilitation Among Patients With Traumatic Brain Injury.American journal of physical medicine & rehabilitationIn 210,440 adults with traumatic brain injury, within-stay readmission rates were similar for men and women. Readmission was linked to older age, complications, lower admission function, and longer time from injury to rehabilitation; racial/ethnic minority patients had longer delays and stays before readmission.
• OTCohort2022The Association Between Payer Source and Traumatic Brain Injury Rehabilitation Outcomes: A TBI Model Systems Study.The Journal of head trauma rehabilitationIn 8,558 adults under age 64 with moderate to severe TBI, worker's compensation/auto stayed longest in inpatient rehabilitation and had highest discharge independence, while uninsured stayed shortest. The insurance difference in discharge independence was no longer seen when length of stay was included.
• PTOTNarrative Review2022Effects of Exercise Mode on Improving Cardiovascular Function and Cardiorespiratory Fitness After Bariatric Surgery: A Narrative Review.American journal of physical medicine & rehabilitationAerobic exercise improves cardiorespiratory fitness in bariatric surgery patients, often without additional weight loss. Resistance training alone did not improve fitness but helped maintain muscle. Combining both is recommended to maximize health benefits and prevent muscle loss, though evidence remains limited and protocols need standardization.
• PTOTSLPSurvey2022Association Between Self-Reported Disability and Lifetime History of Traumatic Brain Injury With Loss of Consciousness Among Veterans and Nonveterans in North Carolina.The Journal of head trauma rehabilitationVeterans and nonveterans reporting a lifetime history of traumatic brain injury with loss of consciousness had higher rates of current disability. Cognitive, independent living, and vision disabilities showed the strongest associations. This identifies a group needing careful functional assessment, but does not prove the injury caused the disability.
• PTOTSLPOther2023Views of in-person and virtual group exercise before and during the pandemic in people with Parkinson disease.PM & R : the journal of injury, function, and rehabilitationPeople with Parkinson disease who moved from in-person to virtual group exercise reported maintaining or improving mobility and balance. They valued the social connection and convenience of Zoom classes, though few had been referred to the program by a doctor.
• PTOTCohort2022Prediction of bowel management independence after ischemic spinal cord injury.European journal of physical and rehabilitation medicineA single motor strength score taken within 40 days of ischemic spinal cord injury predicted who would regain independent bowel management at one year. The model showed fair accuracy but missed many patients who would not recover, so use it to guide expectations rather than to rule out need for support.