PTOTSLPCase-ControlJournal of autism and developmental disorders2025

The Relationship Between Fatigue and Quality of Life in the Turkish Mothers of Children with Autism Spectrum Disorder.

Koray Kara, Ozgun Kaya Kara, Gulsah Sutcu and 1 others

PMID 38764072

WHAT IT FOUND

Mothers of children with autism reported significantly greater fatigue impact on their daily functioning and lower quality of life than mothers of typically developing children.

Their own perceived quality of life and physical mobility were the strongest predictors of this fatigue, rather than how disruptive they found their child's specific behaviors.

Key findings

01Mothers of children with ASD had significantly higher scores for the cognitive, physical, and psychosocial impacts of fatigue, depression, and poor health-related quality of life compared to controls.

02A mother's own perceived quality of life and physical mobility were the strongest factors associated with the impact of fatigue on her cognitive function, explaining 66.7% of the variance.

03The mothers' perception of how much of a problem their child's ASD-related behaviors were for them (QoLA Part B) was not significantly associated with fatigue in the multivariate analysis.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

The study used a cross-sectional design, so it cannot determine if poor quality of life causes fatigue or vice versa. The control group was recruited via snowball sampling, which may introduce selection bias. The broad age range of children (2-18 years) means caregiving demands varied significantly. No data on the severity of the children's ASD or specific behavioral profiles was reported, which limits understanding of how child factors interact with maternal fatigue.

Declared interests

The study was funded by the University of Health Sciences. No other conflicts of interest were declared.

The easy way to misread this

Do not assume that reducing the child's disruptive behaviors will directly lower the mother's fatigue. The study found that the mother's own perceived quality of life and physical mobility were much stronger predictors of her fatigue impact than her perception of the child's specific autism-related problems.

Read it on PubMed →