PTOTCohortNeurorehabilitation and neural repair2023

The Evolution of Hand Proprioceptive and Motor Impairments in the Sub-Acute Phase After Stroke.

Monika Zbytniewska-Mégret, Christian Salzmann, Christoph M Kanzler and 4 others

PMID 37953595

WHAT IT FOUND

Hand proprioception and motor function often recover independently after stroke.

Only 42% of patients showed matched changes in both. Patients with poor hand use at baseline had less proprioceptive recovery. Assess and treat these systems separately rather than assuming one drives the other.

Key findings

01Dissociated recovery patterns were frequent: 42% of all participants and 25% of those with measurable baseline impairment improved in either proprioception or motor function, but not both.

02Baseline functional hand use, not baseline proprioceptive error, predicted how much proprioception improved. Patients with higher Box and Block scores showed greater gains in position sense.

03Absent somatosensory evoked potentials (SSEP) were linked to a lack of proprioceptive improvement, while preserved SSEP was seen in all patients who did improve in position sense.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

The study only assessed the index finger, so results may not generalize to the whole hand or proximal joints. Participants were included at different times since stroke (average 34 days), though this was not found to significantly influence the results in the statistical model. The definition of 'motor improvement' relied on three different robotic metrics, while 'proprioceptive improvement' relied on only one, which may create a slight imbalance in how improvement was categorized. This was an observational study of usual care; it did not test whether specific interventions could change these recovery patterns.

Declared interests

The authors declared no potential conflicts of interest. The work was funded by the Swiss National Science Foundation, the Deutsche Forschungsgemeinschaft, and the National Research Foundation (Singapore).

The easy way to misread this

Do not interpret the lack of correlation between proprioceptive and motor changes as evidence that one does not influence the other in the long term. This study observed spontaneous recovery and usual care over a short window (2-4 weeks). It shows that these systems can recover independently during this phase, but it does not rule out that targeted sensory training might eventually improve motor outcomes, or that combined deficits might hinder later complex task learning.

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