PTOTMeta-AnalysisJournal of neuroengineering and rehabilitation2026

The effectiveness of robotic therapy in reducing upper limb spasticity in stroke survivors: a systematic review and meta-analysis.

Salvatore Facciorusso, Alberto Esquenazi, Franco Molteni and 2 others

PMID 41772621

WHAT IT FOUND

Robotic therapy produced small reductions in elbow and wrist flexor tone compared with conventional therapy, but not shoulder tone.

Hand-only devices did not reduce tone, and daily independence did not clearly improve.

Key findings

01Elbow flexor spasticity scores were 0.25 points lower after robotic therapy than conventional therapy overall, and 0.36 points lower in chronic stroke.

02Wrist flexor spasticity scores were 0.22 points lower after robotic therapy than conventional therapy, with low certainty.

03Shoulder adductor spasticity did not show a significant reduction, and hand-only devices did not show a significant reduction in spasticity.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

All included trials were judged at high risk for performance bias because participants and therapists could not be blinded. Many trials did not clearly report allocation concealment, so selection bias cannot be ruled out. The certainty for wrist, shoulder, unspecified and hand-device spasticity results was low or very low. Robot type, dose, timing, and whether robotics replaced or added to conventional therapy varied widely. The main spasticity measure was the Modified Ashworth Scale, which limits conclusions about physiological tone changes. Adverse event reporting was incomplete, and the certainty for safety was very low. The search was limited to English-language publications.

The easy way to misread this

Do not use robotic therapy mainly as an anti-spasticity intervention. The reductions were small, not seen for shoulder adductors or hand-only devices, and the review positions robotics as a way to increase motor practice rather than a primary tone treatment.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →