PTOTSLPCohortDevelopmental medicine and child neurology2026

Surgical and health outcomes of non-ambulatory children with cerebral palsy and severe scoliosis: A population-based, longitudinal study.

Svend Vinje, Terje Terjesen, Joachim Horn and 2 others

PMID 40836580

WHAT IT FOUND

Spinal fusion in non-ambulatory children with severe cerebral palsy scoliosis corrected curves and improved seating and pain for most, but carried high complication and mortality risks.

Caregivers of survivors reported high satisfaction, though non-surgical children were too frail for comparison.

Key findings

01Seating posture improved in 29 of 30 children who had preoperative problems, and back pain relief was reported in 15 of 22 children with preoperative pain.

02Eighteen of 38 surgically treated children experienced postoperative complications, including respiratory issues in 11, and four died during follow-up.

03Among children deemed too fragile for surgery, the mortality rate was 48%, with pneumonia or respiratory disease the most common cause of death.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

The study was retrospective and non-randomised, meaning the surgical and non-surgical groups were fundamentally different in health status, making direct comparison of outcomes like quality of life unreliable. A significant portion of the non-surgical group died before follow-up, introducing survivorship bias in the quality of life data. There was no preoperative quality of life assessment, so it is impossible to determine how much the surgery itself changed the child's overall well-being over time. The sample size was small (75 children), and clinical data relied on subjective registry entries and case records, leading to some missing information.

Declared interests

The authors declared no conflicts of interest. The study received open access funding from Oslo University Hospital.

The easy way to misread this

Do not interpret the higher quality of life scores in the surgical group as proof that surgery improves quality of life compared to no surgery. The non-surgical group consisted largely of children who were too medically fragile to survive the operation, so their lower scores reflect their baseline health and higher mortality risk, not the effect of the treatment.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →