PTOTSystematic ReviewJournal of neuroengineering and rehabilitation2026

Post-stroke lower limb rehabilitation: a comparative study between exoskeleton robots and traditional gait training.

Wenzhu Xu, Nai Yeen Gavin Lai, Kok-Hoong Wong and 2 others

PMID 42104373

WHAT IT FOUND

Robot-assisted gait training may speed short-term recovery in severe post-stroke walking deficits, while traditional training better supports active movement learning.

Most evidence lacked follow-up beyond six months.

Key findings

01Robot-assisted gait training was reported to improve gait symmetry, walking speed and range of motion more than traditional gait training, but may suppress movement variability.

02Traditional gait training was reported to strengthen active participation and volitional control, and its muscle synergy patterns were closer to natural gait than robot-assisted training.

03Long-term evidence was limited: most included studies reported only immediate post-intervention outcomes, and over 96% lacked follow-up beyond six months.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

The review did not combine results into a pooled effect size because the included studies varied in stroke stage, intervention duration and exoskeleton type. Most included studies reported only immediate post-intervention outcomes, and over 96% lacked follow-up beyond six months. Twenty-three percent of RCTs were rated high risk of overall bias, mainly for outcome measurement and selective reporting. The radar-chart scores from 0 to 10 were evidence synthesis tools, not statistical effect sizes, and involved interpretive judgment. Robot outcomes depended on the control strategy: fixed-trajectory assistance sometimes produced inferior or equivalent results to traditional training, while assist-as-needed protocols showed advantages. The staged strategy of traditional training in the acute phase and robot training in the subacute phase is a recommendation by the authors, not a tested intervention in this review. Cost and limited multi-planar movement were noted as practical barriers to broad adoption.

Declared interests

The supplied text lists several funding sources: Zhejiang Province Traditional Chinese Medicine Project, Key Project at the Hospital Level of Ningbo Rehabilitation Hospital, Science and Technology Project of Yinzhou District, Ningbo Public Welfare Project, Key Research and Development Project of Ningbo City, and Zhejiang Public Welfare Project. It does not provide an author conflict-of-interest declaration.

The easy way to misread this

Do not conclude that exoskeleton robots are better than traditional gait training for every stroke patient. The review did not combine results into a pooled effect size, many studies found both groups improved, and robot superiority was reported mainly in short-term outcomes and more severe impairment, with little follow-up beyond six months.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →