OTSystematic ReviewWork (Reading, Mass.)2025

Occupational therapy interventions in facilitating return to work in patients with traumatic brain injury: A systematic review.

Abigal Mullins, Olive Scalise, Brianna Carpio-Paez and 5 others

PMID 39973647

WHAT IT FOUND

The reviewers conclude that return-to-work rates were highest when vocational and cognitive rehabilitation were combined with a multidisciplinary team, and clients said OT advocacy with employers helped most.

But the evidence is thin: the highest-quality trial found no difference at 12 months.

Key findings

01The reviewers' own conclusion is that return to work was most likely when occupational therapy combined vocational and cognitive rehabilitation, alongside a multidisciplinary team and the Model of Occupational Self-Efficacy.

02The randomised trials were mixed on work itself: a 10-week group cognitive training programme plus supported employment gave higher return-to-work rates at 3 months but no difference at 6 or 12 months, and a virtual reality vocational training programme gave no vocational advantage over a trainer-led programme.

03The included evidence is small and uneven: five of the 15 studies were rated Level 4b, including case series and a single case study, and the review did not exclude any study on the basis of its evidence level.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

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What it does not show

Nothing was pooled. The review describes 15 studies one at a time, so the figures cannot be combined, and the positive conclusion rests on a handful of them. The randomised trials with return to work as the outcome were negative at their main time point, and the positive work figures come from a non-randomised cohort, a non-randomised comparison and a single case report, none of which can show the intervention caused the change. The evidence is small and uneven. Several studies had fewer than 20 participants and one had a single person, five studies were rated Level 4b, and no study was excluded because of its evidence level. Several studies were not blinded and relied on self-reported outcomes. Most interventions were packages given by whole teams, so what occupational therapy contributed on its own cannot be separated from physiotherapy, neuropsychology, vocational counselling and supported employment. The settings differ from most readers' services: three studies were run in Cape Town, one in Denmark and one in Hong Kong, and the authors note that Hong Kong was said to have insufficient employment services for people with traumatic brain injury. At least one quality rating does not fit the design it was applied to: a randomised trial is described in the results as assessed with the qualitative CASP checklist.

Declared interests

The authors state that they received no financial support for the research, authorship or publication of the article, and that they declared no potential conflicts of interest.

The easy way to misread this

Do not read this review as evidence that occupational therapy vocational or cognitive interventions get people back to work. The largest trial with return to work as its main outcome, 116 people, found no difference between groups at 6 or 12 months; a randomised trial of 40 people found no vocational advantage from virtual reality training; and the positive work figures come from a non-randomised Danish cohort of 32 people and a single case study of one man. The review describes its own evidence as only moderate strength.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →