PTOTSLPCohortJournal of autism and developmental disorders2026

Moderate-to-Vigorous Physical Activity and Suicidal Ideation in Adolescents with Attention Deficit/Hyperactivity Disorder: the Mediating Effects of Mental Health.

Chang Liu, Yijian Yang, Kelly Arbour-Nicitopoulos and 4 others

PMID 40253674

WHAT IT FOUND

Adolescents with ADHD who engaged in more moderate-to-vigorous physical activity reported lower suicidal ideation.

This link was fully mediated by depression, anxiety, and resilience. Increasing physical activity may reduce suicidal thoughts by improving these mental health factors.

Key findings

01Moderate-to-vigorous physical activity (MVPA) was negatively associated with suicidal ideation (SI) in adolescents with ADHD.

02Depression fully mediated the association between MVPA and SI; the direct effect of MVPA on SI was not significant after adjustment.

03Anxiety and resilience also mediated the link between MVPA and SI through a chain effect involving depression.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

Small sample size (n=60 analysed) may lead to underpowered results. Cross-sectional design prevents causal inference; MVPA may not cause reduced SI. Highly unbalanced sex distribution (52 males, 8 females) limits generalisability and examination of sex differences. Participants were excluded if they had other health conditions or were on medication, potentially limiting applicability to the broader ADHD population. ADHD subtypes and symptom severity were not analysed, which may influence outcomes.

Declared interests

Funding was provided by the General Research Fund from the University Grants Committee of Hong Kong and the Laureus Sport for Good Foundation. The authors declared no conflicts of interest.

The easy way to misread this

Do not interpret these findings as proof that physical activity directly prevents suicidal ideation. The study is cross-sectional, so it shows an association, not causation. Furthermore, the direct link between activity and suicidal thoughts disappeared when depression was accounted for, suggesting activity works through mental health improvements rather than acting on suicidal thoughts alone.

Read it on PubMed →