Longitudinal development of hand use in children with unilateral spastic cerebral palsy from 18 months to 18 years.
Ann-Christin Eliasson, Linda Nordstrand, Magnus Backheden and 1 others
PMID 35899928WHAT IT FOUND
Hand function in unilateral CP stabilizes around age 7 and remains steady through adolescence.
Higher-functioning children reach their plateau earlier, but all groups maintain their bimanual ability. Regular follow-ups are essential because individual variation remains large.
Key findings
01Bimanual hand performance stabilizes from approximately age 7 through age 18 across all Manual Ability Classification System (MACS) levels.
02Children in MACS level I reached 90% of their maximum hand function at an average age of 28 months, compared to 37 months for level II and 62 months for level III.
03The maximum achievable hand function (limit) differed significantly by severity, with MACS level I reaching a mean of 76.9 AHA units, level II 57.0 units, and level III 49.8 units.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTs
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What it does not show
The study used a convenience sample recruited from habilitation centers and hospitals, which likely included children with more severe impairments and excluded those with mild impairments who had minimal contact with services. The number of assessments varied widely between children (range 2–16), and older age groups had fewer participants, making estimates for adolescents less reliable. Interventions such as constraint-induced movement therapy, hand surgery, and botulinum toxin were common among participants but were not controlled for in the statistical models, so it is unclear how these treatments influenced the observed trajectories. The findings may not generalize to populations with different access to habilitation services or different geographical contexts.
Declared interests
Funding was provided by Norrbacka-Eugeniastiftelsen, Stiftelsen Frimurare Barnhuset i Stockholm, Stockholm City Council, and the Swedish Research Council. No conflicts of interest were declared.
The easy way to misread this
Do not assume that hand function remains stable for every individual. While the group averages showed stability from age 7, the study found large individual variation, meaning some children may improve or decline. Regular clinical follow-up is necessary to detect these individual changes.