PTOTSLPSystematic ReviewResearch in developmental disabilities2026

Communicative Development Inventories (CDIs) in etiologically diverse developmental conditions: A systematic review.

Zuzanna Laudańska, Patrice van der Venne, Helena Preis and 10 others

PMID 41707555

WHAT IT FOUND

CDIs reliably flag delayed expressive vocabulary in autism and Down syndrome, but standard scores often underestimate ability when children use signs or have low intelligibility.

Use longitudinal tracking for progress, not single-timepoint screening, and adapt forms to include gesture.

Key findings

01Children with autism show delayed expressive vocabulary compared to low-likelihood peers, with significant heterogeneity in trajectories including regression or plateaus.

02In Down syndrome, expressive vocabulary lags significantly behind typically developing peers, and standard spoken-word reports may underestimate ability if sign use or low intelligibility is not accounted for.

03CDIs are not yet validated as standalone diagnostic screening tools for language difficulties in neurodevelopmental conditions due to insufficient diagnostic accuracy in standard forms.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

Most included studies were cross-sectional with only 1–2 timepoints, limiting the ability to draw robust conclusions about developmental trajectories. There was significant heterogeneity in CDI versions (Words and Gestures, Words and Sentences, short forms) and languages used, making cross-condition and cross-linguistic comparisons difficult. Many studies did not report raw scores, interquartile ranges, or consistent documentation of which CDI version was used, restricting data extraction. Parental reporting biases were noted, with parents potentially under- or over-estimating skills depending on the child's condition and their own expectations. The review excluded language-specific conditions like Developmental Language Disorder, limiting generalizability to those populations.

Declared interests

No specific funding sources or conflicts of interest were declared in the provided text.

The easy way to misread this

Do not use standard CDI scores as a definitive diagnostic screening tool for language disorders in neurodevelopmental conditions. The review found insufficient evidence for their diagnostic accuracy in this role, and scores can be misleadingly low if they do not account for sign use, intelligibility, or specific condition profiles like those in Down syndrome or Angelman syndrome.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →