PTOTCase ReportFrontiers in rehabilitation sciences2025

Case Report: Robot-assisted gait training with the wearable cyborg hybrid assistive limb 2S size in three children with cerebral palsy.

Kazushi Takahashi, Hirotaka Mutsuzaki, Tomohiro Nakayama and 9 others

PMID 40196169

WHAT IT FOUND

Three children with cerebral palsy showed improved hip and knee extension angles and altered muscle activity after robot-assisted gait training.

The wearable HAL device appeared to facilitate these biomechanical changes, but this small case series cannot prove the treatment works or compare it to standard therapy.

Key findings

01All three participants demonstrated changes in lower limb joint angles and muscle activity following the intervention.

02The child who walked independently showed improved maximum hip extension and increased gluteus maximus muscle activity.

03The two children using walkers showed improved hip and knee extension angles, with one case demonstrating reduced muscle co-contraction in the leg.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

This is a case report with only three participants, so the results cannot be generalized to the broader cerebral palsy population. There was no control group, so it is impossible to know if the changes were due to the robot, the intensity of the training, or natural development. The participants were hospitalized solely for the study and prohibited from other rehabilitation, which does not reflect typical community-based practice. Muscle activity was normalized to peak walking values rather than maximal voluntary contraction, which may affect the interpretation of the electromyography data. The study is a secondary analysis of a larger trial, which may introduce selection bias.

Declared interests

The study was funded by the Japan Agency for Medical Research and Development (AMED). The authors declared financial support was received for the research and/or publication.

The easy way to misread this

Do not conclude that robot-assisted gait training is superior to conventional therapy or effective for all children with cerebral palsy. This report describes changes in three individuals without a control group, so it cannot rule out other causes for the improvements or predict how other patients will respond.

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