What the Proportional Recovery Rule Is (and Is Not): Methodological and Statistical Considerations.
Robinson Kundert, Jeff Goldsmith, Janne M Veerbeek and 2 others
PMID 31524062WHAT IT FOUND
A rule that people recover a fixed share of upper-limb function after stroke may describe group averages, but reviewed studies do not prove it predicts any one patient.
Key findings
01The proportional recovery rule is a population-level regression model, not a proven universal biological rule; it is best supported for upper-limb motor recovery.
02The original rule said patients recover about 70% of the upper-limb impairment present early after stroke, but that estimate came from a multivariate regression reduced to a single predictor; one later study reported 78%, and the authors' reanalysis suggested an estimate as high as 85%.
03For outcomes other than upper-limb motor function, the reviewed data did not closely match the expected proportional recovery pattern, and some analyses did not clearly identify patients who did not recover.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs
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What it does not show
This is a selective methodological review, not a new clinical trial and not a systematic review, so it cannot establish how well the rule works in practice. The authors extracted data from published figures, so some overlapping points could not be identified and the reanalysed datasets may not exactly match the originals. Studies used different methods to label nonrecoverers, including outlier removal, initial score cutoffs, corticospinal tract integrity, and clustering, which makes comparisons difficult. Some datasets showed ceiling effects and uneven error spread, which can make a proportional recovery pattern look valid when it may not be. The paper focuses on group-level regression and does not provide validated individual patient prediction.
Declared interests
The authors declared no potential conflicts of interest and received no financial support for the research, authorship, or publication.
The easy way to misread this
Do not read the proportional recovery rule as a validated way to predict an individual patient's recovery. The review found that many studies were consistent only at the group level, and that uneven error spread, ceiling effects, and inconsistent methods for separating recoverers from nonrecoverers can make the rule look stronger than it is.