PTOTRCTJournal of neuroengineering and rehabilitation2026

Unlocking trunk potential after stroke: a novel approach combining transcranial direct current stimulation and core stability exercise: a randomized controlled trial.

Abd El-Hamied Ibrahim El-Sayed Mohammad El-Sherbini, Saher Lotfy Elgayar, Mohammed Youssef Elhamrawy and 1 others

PMID 41964055

WHAT IT FOUND

Adding brain stimulation to core stability exercises improved trunk control, balance, and daily independence more than exercises alone in chronic stroke patients.

Both groups gained, but the combined group showed larger improvements across all measures after 12 weeks.

Key findings

01The combined tDCS and CSE group showed significantly greater improvement in trunk control (Trunk Impairment Scale) than the CSE-only group, with a large effect size.

02The combined group also demonstrated significantly greater gains in postural control, balance, and functional independence (Barthel Index) compared to the control group.

03Improvements in trunk control were the strongest predictor of gains in functional independence across the whole sample.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

Participants and treating therapists were not blinded to the intervention because there was no sham stimulation control, which may have influenced performance or reporting. The study did not include a group receiving no treatment or standard care only, so it is unclear how much of the benefit is due to the specific combination versus just the exercises. Follow-up was only immediate after the 12-week intervention, so it is unknown if the gains in balance and independence were sustained over time. The sample size was relatively small (60 participants), and all were recruited from a single outpatient clinic, which may limit generalizability.

Declared interests

The study was funded by Beni Suef University. The authors declared no other conflicts of interest.

The easy way to misread this

Do not assume tDCS alone is effective or that these results apply to patients with more severe disability. All participants could walk independently for at least 10 meters and had mild spasticity, so the benefits seen here may not extend to non-ambulatory patients or those with severe motor impairments.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →