PTOTSLPRCTNeurorehabilitation and neural repair2025

Sleep Following a Stroke: Multimodal Evaluation of Sleep Health and Disruptions and Impact on Recovery During Acute Inpatient Rehabilitation.

Jacob Sindorf, Silvia Campagnini, Megan K O'Brien and 6 others

PMID 40326398

WHAT IT FOUND

Sleep improved slightly during acute stroke rehab but remained poor, with 77% of nights disrupted by care tasks.

Better sleep was not associated with greater functional recovery in this cohort. Prioritize reducing environmental noise and interruptions.

Key findings

01Sleep health improved over the stay but remained poor, with high wakefulness and fragmentation throughout.

0277% of nights had at least one sleep disruption, most commonly from vitals, medication, toileting, and tests.

03There was no significant association between sleep health and functional recovery in this cohort.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

Single-site study with patients excluded if they had prior sleep disorders, limiting generalizability. Actigraphy devices were not validated for acute stroke populations. Multiple comparisons were not corrected for, increasing the risk of false positives. Missing data were imputed, introducing some uncertainty. The study was observational, so it cannot prove that sleep causes better recovery.

Declared interests

The authors declared no potential conflicts of interest. The study was part of a larger clinical trial funded by the National Institutes of Health (U.S. Gov't, P.H.S.).

The easy way to misread this

Do not assume that improving sleep will directly lead to better functional recovery. This study found no significant association between sleep health and functional outcomes in this acute inpatient cohort.

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