PTCohortDevelopmental medicine and child neurology2026

Six-minute walk test reference values in ambulatory children with myelomeningocele.

Karina A Zapata, Rosa H Cooksey, Daralyn K Fulton and 3 others

PMID 40556501

WHAT IT FOUND

Reference walking distances for children with myelomeningocele vary widely by lesion level, from 215 meters for mid-lumbar to 420 meters for sacral lesions.

Shorter 1-minute and 2-minute tests strongly predict these results, offering a faster option for busy clinics.

Key findings

01Children with mid-lumbar lesions walked 215 meters, low-lumbar 344 meters, and sacral 420 meters on the 6-minute walk test.

02Distances walked in 1 minute and 2 minutes were strongly associated with the 6-minute distance, suggesting shorter tests can predict full results.

03Children with public insurance or living in more disadvantaged neighborhoods walked significantly fewer meters than those with private insurance or in less disadvantaged areas.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study was conducted at a single center in the southwest United States, so results may not apply to other populations. Data was cross-sectional, so it cannot show how walking distance changes over time in individual children. Almost half of the participants identified as Hispanic, which may limit generalizability to other ethnic groups, although no differences in walking distance were found based on ethnicity.

Declared interests

The authors stated they had no conflicts of interest. The study did not require external funding.

The easy way to misread this

Do not assume that a child's walking distance is poor because it is far below neurotypical norms. The study shows that reference values must be specific to the child's functional lesion level, as even high-functioning children with sacral lesions walk significantly less than typical peers.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →