RNCohortJournal of the American Medical Directors Association2023

Severity of COVID-19 among Residents in Aged Care Facilities in Victoria, Australia: A Retrospective Cohort Study Comparing the Delta and Omicron Epidemic Periods.

Michael Muleme, Bridgette J McNamara, Frances H Ampt and 14 others

PMID 36806486

WHAT IT FOUND

During Omicron, aged-care residents had lower hospitalization and death per case than during Delta, but more cases and deaths overall.

Nurses should not assume mild disease: monitor residents, maintain infection control, and consider vaccination timing.

Key findings

01Hospitalization risk was lower during the Omicron period than during the Delta period: 8.2% versus 24.6%.

02Case fatality risk was lower during the Omicron period than during the Delta period: 11.4% versus 18.7%.

03The Omicron period had more resident cases and deaths overall than the Delta period: 1882 versus 994 cases, and 214 versus 186 deaths.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The Omicron period analysed was much shorter than the Delta period, and early Omicron case reporting relied on rapid antigen tests and a new definition, so some cases may have been missed. Data on comorbidities and frailty were not available, so residents in the two periods may not have been equally vulnerable. The definition of vaccine protection differed between periods: at least 2 doses for Delta and at least 3 doses for Omicron. Some hospitalizations were for outbreak management rather than clinical need, which can make hospitalization risk hard to interpret. This is an observational comparison of epidemic periods, not a controlled trial, so it cannot prove that the variant alone caused the lower severity. Results are from Victorian residential aged care facilities and may not apply to all aged care populations.

The easy way to misread this

Do not read the lower hospitalization and death percentages as proof that Omicron is mild in aged care. The Omicron period had more resident cases and deaths overall, and some hospital transfers were for outbreak management rather than clinical need.

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The study

Participants
86 outbreaks with 994 resident cases in the Delta period and 209 outbreaks with 1882 resident cases in the Omicron period
Certainty of evidence
Low

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Cite

Michael Muleme, Bridgette J McNamara, Frances H Ampt, et al. Severity of COVID-19 among Residents in Aged Care Facilities in Victoria, Australia: A Retrospective Cohort Study Comparing the Delta and Omicron Epidemic Periods. Journal of the American Medical Directors Association. 2023.

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