Sensory over-responsivity: parent report, direct assessment measures, and neural architecture.

The study was retrospective, and not all children received all measures. Only 235 children had both parent report and direct assessment. Experiment 1 groups were not matched on age or cognitive ability. The table reports mean age 9.8 years for typically developing children and 8.9 years for children with neurodevelopmental disorders, with full-scale IQ 111.9 and 101.4. Gender distribution differed between groups. The table reports 66 boys and 62 girls in the typically developing group and 111 boys and 65 girls in the neurodevelopmental disorder group. Parent report is subjective and can be affected by parental bias and recollection. The imaging analysis was small and limited to 39 boys. Sixteen children were excluded for artifacts or movement, and only eight children had tactile over-responsivity imaging data. The brain tract findings were exploratory, and the authors say they require confirmation in larger studies. This study did not test an intervention, so it cannot show whether any treatment changes sensory over-responsivity or brain tracts.

The supplied text lists funding from the Wallace Research Foundation, the Mickelson and Brody Family Foundation, the Gates Family Foundation, the Gretsch Family Foundation, the Glass Family Foundation, the National Institutes of Health, and an SPD community of family and friends. It does not state a commercial sponsor or a conflict-of-interest declaration.

Do not read the three brain tracts as a diagnostic biomarker or a treatment target. The imaging analysis included 39 boys, the tactile over-responsivity group had only eight children and was not analyzed, and the authors say the result requires confirmation in larger studies.