SLPCase-ControlJournal of voice : official journal of the Voice Foundation2022

Resting Respiratory Resistance in Female Teenage Athletes With and Without Exercise-Induced Laryngeal Obstruction.

Nancy Pearl Solomon, Andrea Pham, Sally Gallena and 3 others

PMID 32988702

WHAT IT FOUND

Resting respiratory resistance was lower in teenage female athletes with exercise-induced laryngeal obstruction, but only after removing one outlier.

The main analysis showed no significant difference, so this finding is not yet reliable.

Key findings

01The primary analysis found no significant difference in resting respiratory resistance between the EILO group and controls.

02Removing one outlier and her matched control resulted in a statistically significant difference showing lower resistance in the EILO group.

03The study aimed to replicate a previous finding of lower-than-normal respiratory resistance at rest in this population.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

The study relied on removing an outlier to achieve statistical significance, which weakens the reliability of the finding. The sample size was small (16 pairs initially, 15 after exclusion). The Airflow Perturbation Device is not commercially available, limiting clinical application. The study only included teenage girls, so results may not generalize to boys or adults. The device measures overall respiratory resistance and cannot distinguish between laryngeal, pulmonary, or oral contributions.

Declared interests

No specific funding sources or conflicts of interest are declared in the provided text.

The easy way to misread this

Do not conclude that resting respiratory resistance is a reliable diagnostic marker for EILO. The significant difference was only found after removing an outlier, and the primary analysis was null. This is a replication attempt with mixed results, not a confirmed finding.

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