Repetitive peripheral magnetic stimulation improves severe upper limb paresis in early acute phase stroke survivors.
Shigeru Obayashi, Rina Takahashi
PMID 32508342WHAT IT FOUND
In 19 adults with severe arm weakness after stroke, final FMA scores did not differ significantly between groups.
The rPMS group had higher FMA score gain relative to treatment duration (2.65 versus 1.10).
Key findings
01Final FMA-UE scores were not significantly different between groups (p = 0.90).
02The rPMS group had a significantly higher FMA progress rate than the standard care group after adjustment for treatment duration (2.65 versus 1.10, p = 0.003).
03No adverse events such as pain or discomfort were reported.
STILL TO COME
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What it does not show
The study included only 19 adults, so the results are unstable and could change with a few participants. The paper describes automatic allocation with matching, not random assignment, so differences other than treatment may explain the result. The rPMS group started treatment later than the standard care group (median 9.2 versus 5.8 days from stroke onset, p = 0.039). The rPMS group also received fewer treatment sessions (median 7.8 versus 16.5, p = 0.034), so the positive finding depends on progress rate adjusted for duration rather than final scores. Final FMA scores were not significantly different between groups. Standard care was not described in detail, so readers cannot know what the control treatment involved. Treatment duration varied from 3 to 32 sessions because transfer timing differed. The study was done at one academic medical center and only included people with severe upper limb paresis in early acute stroke. There was large variation between participants in how much they improved.
Declared interests
No conflicts of interest were reported.
The easy way to misread this
Do not conclude that rPMS is proven to improve final upper limb function. The final FMA scores did not differ significantly between groups, and the positive result came from score gain adjusted for treatment duration in a small study with no randomisation described.