PTOTOtherJournal of rehabilitation medicine2022

Pre-stroke physical activity in relation to post-stroke outcomes - linked to the International Classification of Functioning, Disability and Health (ICF): A scoping review.

Adam Viktorisson, Malin Reinholdsson, Anna Danielsson and 2 others

PMID 34904691

WHAT IT FOUND

Higher physical activity before stroke was linked to better walking, independence, less depression and fatigue, and lower mortality in some studies, but some other studies found no link.

The evidence is mostly observational, so cause cannot be inferred.

Key findings

01The review included 35 studies, and all were rated at moderate to critical risk of bias.

02Being physically active before stroke was not related to adverse outcomes in any study.

03Higher pre-stroke activity was associated with less disability and greater independence in daily activities in some studies, while other adjusted analyses found no association.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

All included studies were rated moderate to critical risk of bias, mainly because of missing data, excluded cases and inadequate adjustment for confounding factors. Pre-stroke activity was self-reported in every study, and all but five studies collected it retrospectively, so recall and selection bias are likely. No study used objective measurements of pre-stroke activity, and several studies did not adequately report intensity, duration and frequency. All studies except one reported analyses with a majority of ischaemic stroke cases, so the findings cannot be extended to haemorrhagic stroke. The scoping review included studies despite high risk of bias and did not provide a single answer to a specific research question. The review did not account for confounding factors, treatment groups and interventions needed to interpret the strength of associations.

The easy way to misread this

Do not conclude that pre-stroke activity causes better stroke recovery. The included studies were mostly observational, used self-reported activity, and had moderate to critical risk of bias, so causal inference is not possible.

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