Post-stroke facial palsy: Prevalence, recovery patterns within the first 7 days, risk factors, and effect of hyperacute treatments.
Zewen Lu, Havva Sumeyye Eroglu, Halvor Naess and 5 others
PMID 41186499WHAT IT FOUND
Facial palsy affects 43% of stroke patients on admission, but only 37% recover fully within the first week.
Older age and severe motor or sensory impairments predict slower recovery. While thrombolysis was linked to better outcomes, this may reflect patient selection rather than treatment effect.
Key findings
01Facial palsy was present in 43% of stroke patients on admission, with most cases being minor or partial paralysis rather than complete paralysis.
02Only 37% of patients with facial palsy recovered fully within 7 days, with greater motor and sensory impairments associated with slower recovery.
03Intravenous thrombolysis was associated with improved recovery, but this link may be confounded by the fact that treated patients often had earlier, milder, or more transient symptoms.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs
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What it does not show
The study was conducted at a single centre, which may limit generalisability to populations with different case-mixes or admission pathways. Recovery analysis started from the first facial palsy assessment, not the time of symptom onset. This 'left truncation' means patients who recovered very quickly before assessment were missed, potentially making recovery rates appear slower than they are. The association between intravenous thrombolysis and better recovery may be confounded by selection bias, as treated patients often had known, early onset times and potentially more transient symptoms. Facial palsy severity was assessed using the NIHSS, which is not as detailed as specialised facial movement scales, potentially affecting the precision of severity grading. The study only looked at the first 7 days, so long-term recovery patterns and outcomes are unknown.
Declared interests
The authors declared no financial support and no potential conflicts of interest.
The easy way to misread this
Do not interpret the association between intravenous thrombolysis and improved facial palsy recovery as proof that the drug treats the palsy directly. The authors note that patients eligible for thrombolysis often had earlier, more transient symptoms that might have resolved anyway, so the benefit may reflect patient selection rather than a specific treatment effect on the facial nerve.
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