OTMeta-AnalysisJournal of developmental and behavioral pediatrics : JDBP2022

Perinatal Physiological and Psychological Risk Factors and Childhood Sleep Outcomes: A Systematic Review and Meta-analysis.

Ying Dai, Kimberly Kovach Trout, Jianghong Liu

PMID 36067425

WHAT IT FOUND

Prenatal alcohol, tobacco and preterm birth, and depression before or after birth were each linked to more sleep problems and shorter sleep in children.

Maternal anxiety, caffeine and opioid maintenance treatment were not. This is risk-factor evidence; no treatment was tested.

Key findings

01Children whose mothers had depression symptoms during pregnancy or after birth slept for shorter stretches and had more sleep problems in the first two years.

02Prenatal alcohol exposure and prenatal tobacco smoking were each linked to shorter child sleep duration and more parent-reported sleep problems.

03Preterm children were more likely to have parent-reported sleep problems, but studies disagreed about whether preterm birth changed sleep duration, bedtime or night waking.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

Read the rest of this summary

You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.

Already have one?

What it does not show

Most pooled results rested on only two or three studies, so the reviewers could not check whether findings held in different age groups, and could not test whether discouraging results went unpublished. Most sleep outcomes came from parents filling in questionnaires about their child's sleep, which relies on recall and may not match what the child actually does at night; a study that recorded sleep overnight found no link between mothers' depression and night waking that the questionnaires did show. Studies contradicted each other on preterm birth and sleep duration, bedtime and night waking, so no clear answer can be given on those. Several studies did not say which other factors they adjusted for, so some of these links may reflect things the researchers did not measure. Only English-language studies were included, and social and environmental factors such as housing and poverty were outside the review's scope. The finding that maternal anxiety was not linked to child sleep rests on three studies, all of which also measured depression, so it may not have the power to separate anxiety from depression.

Declared interests

The paper declares no conflicts of interest. The article text carries no funding statement; it is indexed as receiving NIH extramural research support.

The easy way to misread this

Do not read these as cause and effect. This review pools observational studies, so it can show that a mother's depression, drinking or smoking and a child's sleep problems occur together, but not that one caused the other. Nothing here tested whether treating any of them improves a child's sleep.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →