Applied Evidence

Outpatient rehabilitation can prevent suicide after acquired brain injury.

Journal of rehabilitation medicine · 2026 · Cohort · OT

Ann Karin Margareta Sörbo, Ragnhild Ingeborg Björklund

PMID 42478904

Zero of 591 brain-injury patients in a multidisciplinary outpatient programme died by suicide, versus 40 (26 verified) in 2,932 matched controls.

The comparison is observational, not randomised, but the difference is large.

Key findings

1Zero of the 591 patients in the OBIT group died by suicide, compared with 40 (1.4%) in the 2,932-person control group (p = 0.001); restricting to the 26 verified suicides, the difference was 0.9 percentage points (p = 0.015).

2In a medical records review of 102 patients, 70 (69%) experienced depression during treatment, and 42 of the 69 who received depression treatment got both antidepressant medication and psychological contact.

3The OBIT team comprises a doctor, neuropsychologist, counsellor, occupational therapist, and medical secretary; the mean treatment period was 2 years and 6½ months (range 1 month to 8 years).

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What it does not show

Observational design with no randomisation; patients who chose or were referred to the OBIT may differ from those who did not, in motivation, social support, or access to care. The authors have been involved with the OBIT programme for many years and acknowledge this may lead to overinterpretation. No data on pre-injury psychiatric history, substance misuse, or other suicide risk factors for the control group, so it is unclear whether the two groups were comparable on these dimensions. 14 of the 40 control-group deaths are classified as 'probable' (undetermined intent) rather than 'verified' suicides, introducing uncertainty into the denominator. The medical records review covered only 102 of 591 patients, limited by funding and the date records became fully computerised. Single programme, single country; the team composition and Swedish healthcare context may not generalise. The authors estimate the programme 'may have prevented up to 8 or more suicides,' but this is an interpretation, not a measured effect size.

Declared interests

The authors declare no conflicts of interest. However, they note they have been involved with the OBIT programme for many years and acknowledge this may be both a strength and a limitation, with a risk of overinterpreting the results.

The easy way to misread this

Do not read the zero-suicide result as proof that this specific programme prevents suicide. The comparison is observational with no randomisation, the authors have run the programme for years and acknowledge the risk of overinterpretation, and 14 of the 40 control-group deaths are 'probable' rather than 'verified' suicides. The finding is a strong signal, not a causal demonstration.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →