PTOTNarrative ReviewFrontiers in rehabilitation sciences2025

Inducing asymmetric gait in healthy walkers: a review.

Gert Van Der Velde, Henri Laloyaux, Renaud Ronsse

PMID 40166454

WHAT IT FOUND

Researchers reviewed ways to make healthy walkers limp.

Leg length differences and unilateral weights worked best. Sensory tricks like vibration or sound were inconsistent. These methods help test devices before recruiting patients.

Key findings

01Leg length inequity and unilateral ankle weights were the most effective methods for inducing consistent gait asymmetry in healthy walkers.

02Sensory interventions such as vibrotactile, electrical, or auditory stimulation showed mitigated evidence and were not recommended for inducing asymmetry due to inconsistent results.

03Combining multiple perturbations did not produce additional asymmetry effects compared to using a single intervention.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

The review does not compare the induced asymmetries in healthy walkers to actual pathological gait patterns, so it is unclear how well these methods mimic specific conditions like stroke or cerebral palsy. Healthy walkers have fundamentally different sensorimotor functions than patients, so adaptations seen in healthy subjects may not translate directly to clinical populations. There is high heterogeneity in the studies reviewed, with different metrics and timeframes used to measure asymmetry. The scoring of applicability (cost and setup time) is an estimate and may vary by laboratory resources.

Declared interests

The authors declare that no financial support was received for the research and/or publication of this article.

The easy way to misread this

Do not assume that these interventions accurately replicate the gait of patients with neurological conditions. The review explicitly states that healthy walkers were not compared to real patients, and sensorimotor functions remain fundamentally different, so these methods are for preliminary testing in healthy cohorts, not for validating clinical efficacy.

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