PTOtherJournal of neuroengineering and rehabilitation2021

Functional assessment of stretch hyperreflexia in children with cerebral palsy using treadmill perturbations.

Eline Flux, Marjolein M van der Krogt, Jaap Harlaar and 2 others

PMID 34663392

WHAT IT FOUND

Treadmill perturbations during walking successfully evoked stretch reflexes in children with cerebral palsy.

The protocol was feasible and distinguished the group with cerebral palsy from typically developing children at a group level, supporting its use for future research.

Key findings

01The treadmill perturbation protocol was feasible, with no falls and most children completing the assessment despite fatigue.

02Muscle responses increased with perturbation intensity, confirming the protocol evokes stretch reflexes rather than just passive tissue resistance.

03Children with cerebral palsy showed stronger and longer-lasting muscle responses than typically developing children, allowing group-level discrimination.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study included only children with Gross Motor Function Classification System levels I-II, so these findings do not apply to children with more severe mobility impairments. The protocol could only distinguish between groups of children, not individual patients, meaning it cannot yet be used to diagnose or monitor a specific child's spasticity. Three children with cerebral palsy dropped out due to fatigue, indicating the protocol may be too demanding for some children. The time window used to measure reflexes was long, so some of the recorded activity might have been voluntary rather than purely reflexive. The sample size was small, particularly for the group of children who had undergone SDR surgery, which was only three participants.

Declared interests

The study was funded by the Dutch Technology Foundation (Stichting voor de Technische Wetenschappen). No other conflicts of interest are reported in the provided text.

The easy way to misread this

Do not interpret this as evidence that treadmill perturbation testing is ready for clinical use. The study showed the method works at a group level but could not reliably identify stretch hyperreflexia in individual children, and some children with cerebral palsy had responses similar to typically developing peers.

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