Fatigue is Associated with Reduced Participation and Health-Related Quality of Life Five Years After Perimesencephalic Subarachnoid Haemorrhage: A Multicentre Cross-Sectional Study.
Elisabeth A De Vries, Wendy Boerboom, Rita J G Van den Berg-Emons and 4 others
PMID 35191989WHAT IT FOUND
5 years after perimesencephalic subarachnoid haemorrhage, patients with fatigue reported less frequent participation, more restrictions, and worse quality of life.
Fatigue severity stayed associated with these outcomes after depression, anxiety, hypertension and comorbidity were considered.
Key findings
01Fatigued patients scored significantly worse than non-fatigued patients on participation frequency, restrictions and satisfaction, and on total, physical and psychosocial quality of life.
02In adjusted models, more severe fatigue remained significantly associated with lower participation frequency, lower participation satisfaction, and worse health-related quality of life.
0386.7% of fatigued patients versus 16.1% of non-fatigued patients had restrictions in participation.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTs
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What it does not show
The study was cross-sectional, so it cannot show that fatigue caused reduced participation or lower quality of life. Only 46 patients were analysed, and the number of predictors in adjusted models was limited by this sample size. Most patients were discharged home and only 1 patient received inpatient rehabilitation, so the sample may not represent patients in rehabilitation services. Patients had to understand Dutch and did not have serious neurological comorbidity, so results may not apply to people with other comorbidities or other languages. This was a secondary analysis of self-report questionnaire data. Self-efficacy and neuroticism were not measured, although the authors note they can be related to fatigue, quality of life and participation.
Declared interests
The authors have no conflicts of interest to declare.
The easy way to misread this
Do not conclude that treating fatigue will improve participation or quality of life. The study was cross-sectional and did not test a fatigue intervention, so it shows an association, not a cause.