Examining the Role of Behavioral Health Factors on Inpatient Traumatic Brain Injury Rehabilitation Outcomes Among Service Members and Veterans.
Justin T McDaniel, Jolie N Haun, Julie McMahon-Grenz and 8 others
PMID 42769389WHAT IT FOUND
Service members and veterans improved after inpatient traumatic brain injury rehab; alcohol use before admission did not appear to reduce improvement, while tobacco use was linked to slower PTSD symptom improvement.
Key findings
01Participants improved on neurobehavioral symptoms, PTSD symptoms, pain interference, and functioning from baseline to discharge.
02Alcohol use was not associated with change in any outcome after adjustment for age, deployments, and starting score.
03Tobacco use was associated with less improvement in PTSD symptoms, but not with changes in neurobehavioral, functional, or pain outcomes.
STILL TO COME
How it was doneWhat they foundWhat it means for OTs
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What it does not show
The study had no control group, so it cannot show that the rehabilitation program caused the improvements or that tobacco use caused slower PTSD improvement. The sample was mostly men, veterans, and active-duty service members, especially Special Operations Forces, so results may not apply to other people with TBI or PTSD. The analysed sample was a convenience sample, not a randomised or representative group. Data were self-reported and collected in a quality-improvement setting, not a trial, so reporting bias and the study design limit confidence. Alcohol and tobacco use were only recorded before treatment and were prohibited during treatment; the study did not track use over time or measure preinjury substance use, so it cannot separate preinjury exposure from treatment-period effects.
Declared interests
Authors declared payments from Virginia Commonwealth University Partners Against Mortality in Epilepsy, consulting for Ceresant Solutions, funding from the US Department of Veterans Affairs Physical Medicine and Rehabilitation National Program Office, and travel support to the 2026 Society of Behavioral Medicine conference. The study was conducted as a nonresearch quality-improvement initiative under oversight of a VA hospital research and development committee.
The easy way to misread this
Do not read this as proof that quitting tobacco improves PTSD recovery. The study had no control group, relied on self-reported measures, and only showed an association between baseline tobacco use and slower PTSD symptom change.