PTOTRCTJournal of rehabilitation medicine2022

Comparative Effectiveness of Robot-Assisted Training Versus Enhanced Upper Extremity Therapy on Upper and Lower Extremity for Stroke Survivors: A Multicentre Randomized Controlled Trial.

Yingnan Lin, Qin-Ying Li, Qingming Qu and 13 others

PMID 35892319

WHAT IT FOUND

Robot-assisted training was not better than enhanced occupational therapy for arm movement, but it did produce a small, likely non-clinical improvement in leg movement scores.

Both groups improved equally in daily independence. The arm benefit was non-inferior, not superior, so robots are a substitute, not an upgrade.

Key findings

01Robot-assisted training was non-inferior to enhanced upper extremity therapy for the primary outcome of arm motor function.

02Robot-assisted training showed a statistically significant but small difference in lower extremity motor function compared to enhanced therapy, though the authors note this was likely not clinically significant.

03There was no significant difference between the two groups in daily independence (Modified Barthel Index) or proximal arm function.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

Participants were not stratified by time since stroke or level of impairment, so results may not apply to specific subgroups. There were no follow-up assessments to determine if improvements were sustained. The study was not powered to assess cost-effectiveness. The difference in lower extremity improvement was statistically significant but the authors state it was probably not clinically significant as it did not meet the minimal clinically important difference.

Declared interests

The authors declare no conflicts of interest. The study was funded by grants from the Shanghai Science and Technology Committee and the National Natural Science Foundation of China.

The easy way to misread this

Do not interpret the significant difference in lower extremity scores as evidence that robot training improves walking or leg function more than manual therapy. The authors explicitly state this difference was probably not clinically significant because it did not meet the minimal clinically important difference threshold.

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