PTOTSLPCohortFrontiers in rehabilitation sciences2025

Cognitive performance and stroke-specific quality of life four years after stroke.

Marte C Ørbo, Oddgeir Friborg, Audny Anke and 3 others

PMID 41140521

WHAT IT FOUND

Four years post-stroke, quality of life linked only to reaction time, verbal memory, and fine-motor coordination.

Language, executive function, and attention showed no significant association with reported well-being in this small cohort.

Key findings

01Better cognitive-social-mental quality of life scores were significantly associated with faster reaction time, better verbal memory, and better fine-motor coordination.

02No significant associations were found between quality of life scores and language, visuospatial ability, working memory, or executive functions.

03Participants reported high physical health scores but lower cognitive-social-mental scores, indicating persistent psychosocial challenges despite physical recovery.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

The sample was small (65 participants) and predominantly male (74%). Participants were relatively young (under 75) and had mild-to-moderate strokes with high physical functioning, limiting generalisability to older, more disabled, or more severely affected populations. Individuals with aphasia were excluded, so the study cannot speak to the relationship between language impairment and quality of life. The design was cross-sectional at the four-year mark, so it cannot determine whether cognitive deficits caused lower quality of life or vice versa. The type and extent of prior cognitive rehabilitation were unknown, which may have influenced current performance and quality of life ratings.

Declared interests

The study was supported by the Dam Foundation. The funder did not play any role in the study design, data collection, analysis, or manuscript preparation.

The easy way to misread this

Do not conclude that language deficits have little impact on quality of life. Participants with aphasia were explicitly excluded from this study, so the null finding for language reflects the absence of those patients, not the irrelevance of language to well-being.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →