PTCohortDevelopmental medicine and child neurology2026

Biomechanical and functional outcomes of high-burden and low-burden multilevel surgery in young people with cerebral palsy.

Victoria Hinchberger, Brittany A Virgil, Chris Church and 7 others

PMID 41895822

WHAT IT FOUND

Gait pattern improved after both low-burden and high-burden multilevel surgery in ambulatory young people with cerebral palsy.

Functional walking capacity improved only after low-burden surgery; high-burden surgery did not improve walking capacity and walking speed decreased.

Key findings

01Gait Deviation Index improved after both low-burden and high-burden multilevel surgery.

02Low-burden surgery improved walking capacity and walking speed, while high-burden surgery did not improve walking capacity and walking speed decreased.

03Parent-reported global function improved after both low-burden and high-burden surgery, but neither group reached the minimum clinically important difference.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study was retrospective and did not randomise surgical burden, so children selected for more procedures may have differed in ways not measured. Gait analysis timing relative to surgery varied and was not controlled, which can affect baseline and postoperative scores. The high-burden group was older than the low-burden group at surgery, and age may influence recovery and outcomes. The analysis controlled relatively few comorbidities and did not consider cause of cerebral palsy. Strength, motor control, cognition, behaviour, family support, weight-bearing protocols, and rehabilitation details were not fully measured. Walking activity data were missing for 32% of patients before or after surgery. The missing data reduced power for that outcome. Walking activity is a community-based measure of performance and may be affected by environmental factors. Postoperative rehabilitation was given with surgery, and individual surgical procedures were not analysed, so the contribution of any single component cannot be separated.

The easy way to misread this

Do not conclude surgical burden alone caused the functional differences. The high-burden group was older, had more procedures per surgery event, and received postoperative rehabilitation with surgery, so the contribution of age, individual procedures, timing, and rehabilitation cannot be separated.

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