Beyond group differences: Exploring the preliminary signals of target engagement of an executive function training for autistic children.
Sarah R Edmunds, Gabrielle A MacNaughton, M Rosario Rueda and 2 others
PMID 35481725WHAT IT FOUND
Autistic children in the computer executive function training plus metacognitive coaching and caregiver check-in group showed faster lab-based stop-signal reaction time than waitlist children only when ADHD features were clinically significant.
Anxiety did not change who benefited, and brain changes did not explain parent-reported outcomes.
Key findings
01For autistic children with ADHD features at or above T = 70.69, the group receiving computer games plus metacognitive coaching and caregiver check-in had stop-signal reaction times 98 ms faster than the waitlist group.
02Anxiety features did not change the effect of computer games plus metacognitive coaching and caregiver check-in on lab-based behavioral targets.
03The brain measure did not account for the effect of randomization to computer games plus metacognitive coaching and caregiver check-in on parent-reported outcomes, but within the training group it was linked to fewer repetitive behaviors.
STILL TO COME
How it was doneWhat they foundWhat it means for OTs
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What it does not show
The moderation and mediation questions were post-hoc and highly exploratory, and the authors say the findings need replication. The sample size limited power, so a smaller mediation effect could have been missed. The sample was not diverse by race or ethnicity. ADHD and anxiety were measured as questionnaire features, not formal diagnoses. The study did not confirm anxiety diagnoses with a follow-up clinical interview. The training package combined computer games, metacognitive coaching, and caregiver check-in, so the contribution of any single component cannot be separated. The intervention was delivered by graduate students or research assistants, so its fit with typical occupational therapy practice is not shown.
Declared interests
The supplied text states that the Eunice Kennedy Shriver National Institute of Child Health and Human Development funded the work. It does not list author competing interests.
The easy way to misread this
Do not read the 98 ms faster stop-signal reaction time as evidence that the computer games plus metacognitive coaching and caregiver check-in package improves everyday executive function. The effect was exploratory, appeared only in a subgroup with clinically significant ADHD features, and did not explain parent-reported outcomes.