PTOTSLPRNNarrative ReviewThe Nurse practitioner2025

An overview of clinical presentation and management of long COVID.

Sujith Sujith, Noah Gatzke

PMID 41145456

WHAT IT FOUND

Long COVID can be considered when symptoms persist beyond 12 weeks and alternative causes are excluded.

Management is supportive: screen cardiac risk before exercise, use graded exercise, fluids, salt and compression for POTS, and refer to PT, OT, speech and swallowing rehab.

Key findings

01Long COVID can be considered when signs or symptoms develop during or after COVID-19 or an infection consistent with it and persist for longer than 12 weeks after alternative diagnoses are excluded.

02First-line treatment for POTS in long COVID is nonpharmacological: gradual exercise, increased fluids and salt, compression stockings, abdominal binders, counter maneuvers such as leg crossing, and behavioral modifications.

03Referral to multidisciplinary rehabilitation, including physical therapy, occupational therapy, pulmonary or cardiac rehabilitation, and speech and swallowing therapy, is recommended once life-threatening complications and alternative diagnoses are ruled out, with cardiac screening before exercise.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPsWhat it means for RNs

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What it does not show

No original study methods, participants, outcomes or effect sizes are reported. The paper states that specific treatments have not been thoroughly evaluated and empirical evidence is yet to emerge. Management recommendations are drawn from cited sources and expert practice rather than tested interventions. The paper does not provide comparative effectiveness results or patient-level data.

The easy way to misread this

Do not read this as evidence that any specific long-COVID treatment works. It is a narrative overview, and the paper states that specific treatments have not been thoroughly evaluated and empirical evidence is yet to emerge.

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