PTOTSystematic ReviewFrontiers in rehabilitation sciences2022

Adaptations in Muscular Strength for Individuals With Multiple Sclerosis Following Robotic Rehabilitation: A Scoping Review.

Kailynn Mannella, Alan C Cudlip, Michael W R Holmes

PMID 36188915

WHAT IT FOUND

Robot-assisted lower-limb training increased leg strength in all three lower-limb studies; one of two upper-limb studies increased grip force.

Strength was not the main target in these five small studies, so it is not proven as a stand-alone strength treatment.

Key findings

01Lower-limb robot training increased knee-extensor force by 3.5 and 3.3 kg and ankle torque by 11.4 and 10.7 Nm in the included studies.

02In upper-limb robot training, handgrip force and perceived strength increased in one of the two studies.

03Strength was not the targeted outcome in the included studies, and no study reported adverse effects.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

Only five studies met the inclusion criteria, and sample sizes were small, ranging from 6 to 20 participants. Muscular strength was not the primary or targeted outcome in the included studies; it was measured alongside motor or gait goals. None of the included studies reported training volume such as repetitions, sets or load, so clinicians cannot tell what dose produced the changes. The studies did not analyse results by multiple sclerosis phenotype or disability level, so it is unclear who benefits most. The review reported EDSS scores from 6.0 to 8.0, so the findings may not apply to people with milder disability. Follow-up was limited: one lower-limb study returned to baseline at 6 months, and only one study reported a 3-month follow-up improvement.

Declared interests

The authors declared no commercial or financial relationships. One author was supported by the Canada Research Chairs program.

The easy way to misread this

Do not read this as proof that robot-assisted rehabilitation is an effective strength-training program for multiple sclerosis. Strength was not the main target, only three of five studies showed increases, and the papers did not report repetitions, load or progression.

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