TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

3,875 PAPERS · PAGE 41 OF 78 · NEWEST FIRST

• PTOTSLPSystematic Review2022Cognitive impairment, anxiety and depression: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.European journal of physical and rehabilitation medicineCochrane reviews show cognitive training, exercise, and memory rehabilitation can help thinking and mood in stroke, cancer, and dementia. Evidence quality is low to very low. These findings apply to other conditions, not directly to post-COVID-19.
• PTOther2022Active cooling of twisted coiled actuators via fabric air channels.Frontiers in rehabilitation sciencesA fabric channel with forced air cooled artificial muscles for wearable devices faster than passive cooling, but it reduced their movement and slightly increased heating. The work tested bench prototypes only, not stroke patients or rehabilitation exercises.
• PTOTSLPCohort2022Rehabilitation of Patients With Acute Ischemic Stroke Who Required Assistance Before Hospitalization Contributes to Improvement in Activities of Daily Living: A Nationwide Database Cohort Study.Archives of rehabilitation research and clinical translationStarting rehabilitation early and increasing daily duration improved daily living activities in stroke patients who needed help before admission. This benefit held for those with moderate disability, but early rehabilitation did not improve outcomes for the most severely disabled group.
• PTOTSLPRCT2023Optimized Home Rehabilitation Technology Reduces Upper Extremity Impairment Compared to a Conventional Home Exercise Program: A Randomized, Controlled, Single-Blind Trial in Subacute Stroke.Neurorehabilitation and neural repairPatients using a sensor-based home exercise system improved upper limb function more than those using paper instructions. The trial stopped early due to the pandemic with only 25 participants analyzed, so the result is promising but not yet definitive for routine care.
• PTOTSLPQualitative2023Exemplary post-discharge stroke rehabilitation programs: A multiple case study.Clinical rehabilitationExemplary post-discharge stroke care relies on three pillars: deep clinical knowledge, a respectful personalized relationship, and team commitment. Patients valued providers who treated them like friends, explained stroke impacts clearly, and offered flexible timing rather than rigid intensity.
• PTOTSLPCohort2023The Moderating Role of Motivation in the Real-Time Associations of Fatigue, Cognitive Complaints, and Pain With Depressed Mood Among Stroke Survivors: An Ecological Momentary Assessment Study.Archives of physical medicine and rehabilitationFor stroke survivors, feeling tired, in pain, or mentally slow was linked to feeling depressed in the moment. However, doing activities because they were personally meaningful, rather than out of pressure or obligation, weakened this link. Clinicians should support autonomous motivation.
• PTOther2022Playfully Assessing Lower Extremity Selective Voluntary Motor Control in Children With Cerebral Palsy: Psychometric Study.JMIR rehabilitation and assistive technologiesA playful game using leg sensors could separate children with cerebral palsy from peers, but it did not match standard clinical scores well. It may add detail, not replace usual assessment.
• PTOTSLPOther2022Effect of exoskeleton-assisted Body Weight-Supported Treadmill Training on gait function for patients with chronic stroke: a scoping review.Journal of neuroengineering and rehabilitationExoskeleton-assisted treadmill training improved walking in 10 of 11 studies, but it was not better than therapist-assisted training. The robot's value appears to be reducing physical burden on therapists while maintaining similar gait gains, not adding superior efficacy.
• PTOTSLPSystematic Review2022Dysphagia, dysphonia and olfactory disease: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.European journal of physical and rehabilitation medicineNo Cochrane reviews exist for treating voice or smell loss in post-COVID. For swallowing, one review of stroke patients suggests behavioral strategies and TMS may help, but evidence quality is low and does not directly prove these treatments work for post-COVID patients.
• PTOTSLPOther2022Interaction of network and rehabilitation therapy parameters in defining recovery after stroke in a Bilateral Neural Network.Journal of neuroengineering and rehabilitationIn a computer model of stroke, exploratory movements across a full workspace improved reaching accuracy more than repetitive stereotypic movements. This benefit occurred regardless of whether the healthy arm was restrained or used. The model suggests movement variety, not hand selection, drives recovery.
• PTOTCohort2022Characteristics Associated With Perceived Underemployment Among Participants With Spinal Cord Injury.Archives of rehabilitation research and clinical translationAmong employed people with spinal cord injury, 24.6% perceived themselves as underemployed. Higher earnings, health benefits, and being married were linked to lower odds of feeling underemployed, while working in sales or management/professional roles was linked to higher odds.
• PTOTOther2023Psychometric Properties of a New Measure of Upper Limb Performance in Post-Stroke Individuals: Trunk-Based Index of Performance.Neurorehabilitation and neural repairA new measure called IPt combines speed, accuracy, and trunk compensation in stroke reaching. It showed excellent stability over time and could distinguish mild from moderate-to-severe impairment, offering a way to track motor skill changes beyond standard clinical scores.
• PTOTSLPCohort2022Successful Community Discharge Among Older Adults With Traumatic Brain Injury Admitted to Inpatient Rehabilitation Facilities.Archives of rehabilitation research and clinical translationMost older adults with traumatic brain injury return home after inpatient rehab. Those living alone before injury were less likely to succeed than those living with others. Higher motor and cognitive scores on admission predicted a better chance of going home.
• PTOTSLPSystematic Review2022Service Delivery Models for the Management of Pediatric and Adolescent Concussion: A Systematic Review.Archives of rehabilitation research and clinical translationMost concussion studies measure provider habits or costs, not patient recovery. Specialists deliver active exercise and multidisciplinary care, while generalists often lack standardized tools. Telemedicine improves access for rural families but cannot replace in-person neurologic exams.
• PTOTOther2022Assessing Participation in Adolescents With Cerebral Palsy: Comparison of Life-Habits and USER-Participation.Archives of rehabilitation research and clinical translationThe Life-H and USER-Participation agree on how much adolescents with cerebral palsy do, but not on how satisfied they are. Use the USER-Participation for a quick overall picture and the Life-H when you need to find specific daily restrictions or sources of dissatisfaction.
• PTOTSLPCohort2022Factors Associated With Time to Achieve Physical Functional Recovery in Patients With Severe Stroke After Inpatient Rehabilitation: A Retrospective Nationwide Cohort Study in Japan.Archives of rehabilitation research and clinical translationOnly 40.4% of patients with severe stroke achieved physical independence by discharge. Younger age and higher initial motor scores predicted faster recovery. Patients who reached this goal received 10 more minutes of therapy per day than those who did not.
• PTOther2022Defining usual physiotherapy care in ambulant children with cerebral palsy in the United Kingdom: A mixed methods consensus study.Child: care, health and developmentUK paediatric physiotherapists agreed usual care for ambulant children with cerebral palsy includes long-term monitoring, advice, goal setting, sport and activity, and task-specific training. Only two of six proposed exercise interventions reached consensus. It defines usual care. It does not prove effectiveness.
• PTOTOther2022A Scoping Review of the Characteristics of Activity-based Therapy Interventions Across the Continuum of Care for People Living With Spinal Cord Injury or Disease.Archives of rehabilitation research and clinical translationAcross 140 studies, activity-based therapy for spinal cord injury varied widely, with most research done in labs. Intensity was rarely reported. Clinicians should not assume a standard protocol exists; document specific exercises, dosage, and technology used for each patient.
• PTOTCohort2022Longitudinal Median Nerve Ultrasound Changes in Individuals With Spinal Cord Injury and an Age- and Sex-Matched Nondisabled Cohort.Archives of rehabilitation research and clinical translationOne year after spinal cord injury, patients reported more carpal tunnel symptoms than age-matched controls. Ultrasound changes in the median nerve were subtle and mostly appeared in the nondominant hand, suggesting monitoring for symptoms rather than relying on imaging alone.
• PTOTSLPCohort2022Is the Activity Measure for Postacute Care "6-Clicks" Tool Associated With Discharge Destination Postacute Stroke?Archives of rehabilitation research and clinical translationIn 721 people after ischemic stroke, higher mobility and daily-activity scores near discharge were associated with going home rather than a facility. The same scores did not distinguish inpatient rehab from skilled nursing.
• PTOTSLPCohort2022Clarification of Factors Determining Discharge Destination Among Elderly Patients After Stroke With Low Levels of Independence in Activities of Daily Living: A Retrospective Study.Archives of rehabilitation research and clinical translationAmong stroke survivors with severe disability, those who could eat by mouth, had better cognitive scores, and lived with family were more likely to go home. Patients living alone all went to long-term care, regardless of their physical ability.
• PTOTPilot2022Pilot Study of a Fall Prevention and Management Intervention Program for People With Multiple Sclerosis Who Use a Wheelchair or Scooter Full-Time.Archives of rehabilitation research and clinical translationFalls did not change in a way the study could show after a six-session group program for full-time wheelchair or scooter users with MS. Transfer quality, fall prevention strategies, and perceived importance of community participation improved.
• PTOTOther2022The Influence of Age at Pediatric-Onset Spinal Cord Injury and Years of Wheelchair Use on Shoulder Complex Joint Dynamics During Manual Wheelchair Propulsion.Archives of rehabilitation research and clinical translationShoulder movement during wheelchair propulsion changes based on age at injury and years of use. Those injured younger showed specific motion patterns linked to impingement risk as they aged, but pain was not measured.
• PTOTSLPCohort2023The virtual family conference in stroke rehabilitation: Education, preparation, and transition planning.Clinical rehabilitationCarers reported significantly better stroke knowledge, satisfaction with information, and confidence in transition planning after virtual family conferences. Stress levels also improved in most areas. This was a pre-post study without a control group, so it shows feasibility and perceived benefit, not proof of effectiveness.
• PTRCT2023Exercise Training Does Not Attenuate Cardiac Atrophy or Loss of Function in Individuals With Acute Spinal Cord Injury: A Pilot Study.Archives of physical medicine and rehabilitationIn adults with recent spinal cord injury, six months of arms-only or electrical stimulation rowing did not slow left ventricular shrinkage or loss of heart pumping function. Electrical stimulation rowing raised peak oxygen use, but heart structure did not follow.
• PTOTSurvey2022Parent-report health-related quality of life in school-aged children with cerebral palsy: A cross-sectional study.Frontiers in rehabilitation sciencesPortuguese parents of 68 school-aged children with cerebral palsy reported clinically low quality of life in physical well-being, mood and emotions, autonomy, and bullying compared with European norms. Mobility and cognitive impairment were linked to lower scores.
• PTOTOther2023Interpreting the CPASS Trial: Do Not Shift Motor Therapy to the Subacute Phase.Neurorehabilitation and neural repairDo not shift standard stroke rehabilitation to the subacute phase. The trial compared added therapy at different times, not moving care. Standard therapy was already concentrated early. Participants received an average of 27.9 hours of standard therapy in the first two months.
• PTOTSLPCohort2023Returning to Work after Stroke: Associations with Cognitive Performance, Motivation, Perceived Working Ability and Barriers.Journal of rehabilitation medicineStroke survivors with higher cognitive scores, better self-perceived working ability, and fewer perceived barriers were more likely to return to work. Self-assessments predicted return-to-work at 12 months, while early cognitive screening predicted it at 6 months.
• PTOTQualitative2022Wrist-Worn devices to encourage affected upper limb movement in unilateral cerebral palsy: Participatory design workshops.Frontiers in rehabilitation sciencesChildren with unilateral cerebral palsy and their therapists told researchers that wrist-worn devices must look like standard fitness trackers and be easy to fasten with one hand. School policies on phones and trackers were the biggest practical barrier to using them daily.
• PTOTSLPCohort2022Rehabilitation after paediatric acquired brain injury: Longitudinal change in content and effect on recovery.Developmental medicine and child neurologyRehabilitation focus shifts significantly during admission. More active practice predicted faster daily activity recovery. However, teams often swapped emotional support for medical management when early recovery was slow, complicating any simple dose-response link.
• PTOTMeta-Analysis2023Effects of non-invasive brain stimulation on motor function after spinal cord injury: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitationNon-invasive brain stimulation improved lower-limb strength and balance in people with spinal cord injury, but did not improve walking speed, endurance, or upper-limb function. Most participants received concurrent rehabilitation, so the specific contribution of the brain stimulation remains unclear.
• PTOTSLPNarrative Review2023Stroke Rehabilitation in Low- and Middle-Income Countries: Challenges and Opportunities.American journal of physical medicine & rehabilitationStroke rehabilitation in low- and middle-income countries is severely under-resourced, with few therapists and high patient costs. Current guidelines often fail because they are not adapted to local realities. Effective solutions require community-based care, task-shifting to caregivers, and tele-rehabilitation.
• PTOTCohort2023Effects of dynamic body weight support on functional independence measures in acute ischemic stroke: a retrospective cohort study.Journal of neuroengineering and rehabilitationPatients with acute stroke who used dynamic body weight support during therapy gained more functional independence than those receiving standard care. The average gain was 7.8 points higher on the 18 to 126 point FIM scale. This small retrospective study suggests a potential benefit but requires confirmation.
• PTOTSLPOther2023A Learning Health System Infrastructure for Precision Rehabilitation After Stroke.American journal of physical medicine & rehabilitationThis paper describes building a database to track stroke recovery, not testing a treatment. It details how clinicians can enter data consistently, such as labeling fields to prevent mixing up time and speed. It offers no findings on patient outcomes or intervention efficacy.
• PTOTSLPCohort2023Depression, Anxiety, and Suicidality in Individuals With Chronic Traumatic Brain Injury Before and During the COVID-19 Pandemic: A National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems Study.Archives of physical medicine and rehabilitationDepression, anxiety, and suicidal thoughts in people with chronic traumatic brain injury did not increase during the COVID-19 pandemic compared with before it. Symptoms remained stable, though disability and substance use consistently predicted higher distress.
• PTOTSLPCohort2023Relationship Between Nutritional Status and Severity of Cerebral Palsy: A Multicentre Cross-Sectional Study.Journal of rehabilitation medicineUndernutrition affects half of children with cerebral palsy and worsens as motor and eating difficulties increase. Blood tests failed to identify nutritional status, so clinical assessment of eating ability and growth remains essential for screening.
• PTOTSLPCohort2022Declining trends in birth prevalence and severity of singletons with cerebral palsy of prenatal or perinatal origin in Australia: A population-based observational study.Developmental medicine and child neurologyThe number of Australian singletons with cerebral palsy has dropped significantly. This decline was seen in all gestational age groups, but was most pronounced in very preterm and term babies. The proportion of children with bilateral spasticity decreased, while those with dyskinetic or hypotonic presentations increased.
• PTOTSurvey2023Diet, Physical Activity, and Stress Among Wheelchair Users With Multiple Sclerosis: Examining Individual and Co-Occurring Behavioral Risk Factors.Archives of physical medicine and rehabilitationWheelchair users with MS who had two or three behavioral risk factors reported worse depression, anxiety, sleep quality, and health-related quality of life than those with zero or one. Insufficient physical activity was the most common single risk factor, present alone in 28% of participants.
• PTOTOther2023Exaggerated pressor response to static squats in Parkinson's disease (PD) and healthy subjects is likely an individual trait, not influenced by whole body vibration (WBV).NeuroRehabilitationWhole body vibration did not increase blood pressure during squats in people with Parkinson's. The rise in blood pressure was an individual trait, ranging from 10 mmHg in some to 50 mmHg in others, regardless of the vibration.
• PTOTOther2023Exploring high-density corticomuscular networks after stroke to enable a hybrid Brain-Computer Interface for hand motor rehabilitation.Journal of neuroengineering and rehabilitationStroke patients showed weaker brain-muscle coupling and more abnormal muscle recruitment during hand movement attempts than healthy controls. These network features correlated with clinical impairment scores, offering a way to measure motor deficits for guiding future hybrid brain-computer interface therapy design.
• PTOther2022Accounting for the valley of recovery during post-stroke rehabilitation training via a model-based analysis of macaque manual dexterity.Frontiers in rehabilitation sciencesIn two monkeys with motor cortex lesions, a computational model explained the temporary performance drop when switching from a compensatory grip to a precision grip. The model suggests that training that shares overlapping neural pathways between these two skills can prevent this drop.
• PTSLPCohort2023Salivary Cortisol Dynamics After Mild Traumatic Brain Injury.The Journal of head trauma rehabilitationOne week after mild traumatic brain injury, patients had higher resting cortisol and a larger stress response to exercise than uninjured controls. This suggests activity prescriptions should be tailored to individual tolerance rather than following general advice.
• PTOTSLPSystematic Review2023Effect of mobile application types on stroke rehabilitation: a systematic review.Journal of neuroengineering and rehabilitationMobile apps showed inconsistent benefits across stroke outcomes. Therapy apps improved motor paresis and aphasia in small studies, and rehab videos helped exercise adherence. However, neglect, daily living independence, quality of life, and depression showed no clear benefit or mixed results.
• PTOTCohort2023Cost-effectiveness analysis of overground robotic training versus conventional locomotor training in people with spinal cord injury.Journal of neuroengineering and rehabilitationConventional training was more cost-effective for incomplete SCI, while robotic training showed better value for complete SCI. Robotic training had higher costs and therapy minutes. The study did not measure walking ability, only quality-of-life gains and costs.
• PTOTSLPCohort2022Modelling quality of life in children with intellectual disability using regression trees.Developmental medicine and child neurologyDaytime sleepiness and low community participation were the strongest factors linked to poorer quality of life in children with intellectual disability. Eye contact during communication also mattered. These findings suggest clinicians should prioritize screening for sleep issues and facilitating social engagement.
• PTOTRCT2023Comparative effects of kinect-based versus therapist-based constraint-induced movement therapy on motor control and daily motor function in children with unilateral cerebral palsy: a randomized control trial.Journal of neuroengineering and rehabilitationKinect-based therapy matched traditional therapist-led CIMT for hand use and daily function in children with unilateral cerebral palsy, but it reduced trunk compensation during reaching. The small sample and lack of follow-up mean this is promising, not definitive.
• PTOTOther2023The Berlin Bimanual Test for Tetraplegia (BeBiTT): development, psychometric properties, and sensitivity to change in assistive hand exoskeleton application.Journal of neuroengineering and rehabilitationA 9-item bimanual hand test for tetraplegia was feasible, safe, and scored consistently by raters. Scores lined up with self-care and function questionnaires. With a one-hand exoskeleton, average total scores improved in the 10 participants tested, but manipulation did not.
• PTOTOther2023Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults.Journal of neuroengineering and rehabilitationWalking faster improves some stroke gait mechanics but worsens others relative to neurotypical adults. For many patients, fast walking alone does not make their overall gait pattern look like a typical walker's, suggesting speed training needs to be paired with other techniques to fix specific movement faults.
• PTOTSLPCohort2023Visual Problems are Associated with Long-Term Fatigue after Stroke.Journal of rehabilitation medicineStroke survivors with pronounced visual problems were significantly more likely to report severe fatigue years after their stroke. This association held even after adjusting for mood and energy levels. Clinicians should screen for visual deficits in fatigued patients, as treating vision issues may help reduce fatigue burden.
• PTCase-Control2023The use of machine learning and deep learning techniques to assess proprioceptive impairments of the upper limb after stroke.Journal of neuroengineering and rehabilitationMachine learning models sorted people with recent stroke from healthy controls using robotic arm position matching, slightly better than a single overall score. This was a test of analysis methods, not a new stroke diagnosis tool.