PTCase-ControlJournal of neuroengineering and rehabilitation2023

The use of machine learning and deep learning techniques to assess proprioceptive impairments of the upper limb after stroke.

Delowar Hossain, Stephen H Scott, Tyler Cluff and 1 others

PMID 36707846

WHAT IT FOUND

Machine learning models sorted people with recent stroke from healthy controls using robotic arm position matching, slightly better than a single overall score.

This was a test of analysis methods, not a new stroke diagnosis tool.

Key findings

01The 95% cut-off score method flagged 48.4% of stroke participants as impaired on Variability XY and 44% on the overall task score.

02The best machine learning model separated stroke participants from controls with an AUC of 0.900, compared with 0.853 for the overall task score, on a measure where the paper describes 0.5 as chance and the upper-left point (0,1) as perfect classification.

03Variability Y was the most important feature for classification, and Shift XY tended to be the least important.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The classifiers were trained to know a diagnosis that was already established by clinical and imaging assessment. The arm position matching task requires both hemispheres, so a stroke lesion may affect it more than some other proprioceptive tests. People with hemispatial neglect can perform the task poorly, and the authors did not give the models information about neglect. Single robotic parameters overlapped between stroke and control participants, so one parameter alone is hard to interpret. The machine learning models performed only slightly better than the overall task score. The authors note that machine learning methods require large datasets and many hours of data collection. The paper says bias in training data can carry into testing.

Declared interests

Funded by an Ontario Research Foundation Research Excellence grant, CIHR, and a Heart and Stroke Foundation of Canada grant. The supplied text lists funding but no competing interest declaration.

The easy way to misread this

Do not read this as evidence that machine learning can diagnose stroke or guide treatment. The participants already had a clinical stroke diagnosis, and the authors say using kinematics to diagnose stroke is not practical.

Read it on PubMed →