TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

3,875 PAPERS · PAGE 3 OF 78 · NEWEST FIRST

• PTRCT2026Synergy-based Functional Electrical Stimulation for gait rehabilitation in chronic stroke: a pilot study.Frontiers in rehabilitation sciencesHigh-intensity gait training with or without personalized multichannel functional electrical stimulation did not differ significantly on walking speed or endurance. The stimulation group improved endurance after training and at one month, but the study was too small to show a group difference.
• PTRCT2026Feasibility and safety of multi-field functional electrical stimulation for distal upper-limb rehabilitation after subacute stroke: a randomised controlled feasibility trial.Frontiers in rehabilitation sciencesFES-assisted hand therapy was feasible and safe in subacute stroke: all 16 participants completed all sessions, with no serious adverse events. Exploratory motor scores favoured the FES group, but this was not an efficacy trial.
• PTPilot2026Timing in smartphone-guided home stroke rehabilitation with functional electrical stimulation: feasibility of distributed supervision and retrospective comparison with a front-loaded model.Journal of physical therapy scienceHome exercise plus smartphone-guided electrical stimulation training was safe with high adherence. Distributed supervision showed greater sit-to-stand and Timed Up and Go gains than front-loaded supervision, but the groups were not randomized and differed by country.
• PTCohort2026Baseline PTSD and depressive symptoms predict multidimensional recovery after combat-related transtibial amputation: a prospective cohort study.Frontiers in rehabilitation sciencesCombat amputees with more PTSD or depression symptoms at baseline made smaller balance, walking and endurance gains during robotic rehabilitation. Screen psychiatric symptoms at admission, but do not assume treating PTSD or depression will improve recovery.
• PTSLPPilot2026The Aphasia Physical EXercise (APEX) study: feasibility of a new high-intensity functional interval training for stroke survivors with aphasia.AphasiologyHigh-intensity interval training was safe and well attended by 6 stroke survivors with aphasia, but language and cognitive changes did not reach significance; aerobic endurance improved.
• PTOther2017Measurements of Weight Bearing Asymmetry Using the Nintendo Wii Fit Balance Board Are Not Reliable for Older Adults and Individuals With Stroke.Journal of geriatric physical therapy (2001)Wii Fit balance board weight bearing asymmetry readings were moderately consistent but had large error. For older adults and stroke, changes must exceed 8.8% or 13.6% to be confident, so the board is not recommended for this assessment with factory settings.
• PTOTRCT2016Effects of functional and analytical strength training on upper-extremity activity after stroke: a randomized controlled trial.Brazilian journal of physical therapyFive weeks of home-based functional reaching-and-grasping practice improved arm activity more than analytical dumbbell lifting in chronic stroke, and the difference was still seen at 10 months. Strength, range of motion, motor control, and tone did not differ between groups.
• PTOTRCT2016Effect of mirror therapy on upper extremity motor function in stroke patients: a randomized controlled trial.Journal of physical therapy scienceMirror therapy added to conventional stroke rehabilitation improved upper extremity movement ability more than the conventional program with a non-reflecting mirror, but did not improve Brunnstrom stages or self-care independence.
• PTOTSystematic Review2016Incidence, Time Course and Predictors of Impairments Relating to Caring for the Profoundly Affected arm After Stroke: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapyNo included study predicted difficulty caring for the arm after stroke. Spasticity and pain appeared as early as 1 week, and contracture by 2 weeks. Weakness and reduced motor control predicted spasticity and contracture; reduced sensation, shoulder subluxation, weakness, and stroke severity predicted pain.
• PTOTOther2016Effect of Segmental Trunk Support on Posture and Reaching in Children With Cerebral Palsy.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy AssociationSupporting the trunk at the ribs, not the pelvis, improved reaching for children with moderate CP. Severe CP required high axillary support for posture. Mild CP showed no benefit from any trunk support. Match the support height to the child's specific trunk control deficit.
• PTOTOther2016Quantifying six-minute walk induced gait deterioration with inertial sensors in multiple sclerosis subjects.Gait & postureA hip-worn sensor detected gait deterioration in people with multiple sclerosis that walking speed missed, particularly in later minutes of the six-minute walk. This suggests two-minute tests may be too short to capture fatigue-related changes in mild cases.
• PTSLPCohort2016Balance, Body Motion, and Muscle Activity After High-Volume Short-Term Dance-Based Rehabilitation in Persons With Parkinson Disease: A Pilot Study.Journal of neurologic physical therapy : JNPTThree weeks of high-volume Adapted Tango was feasible in 22 people with Parkinson disease. Some balance and disease severity scores improved, but walking speed and several other outcomes did not change. Without a control group, this is not proof the dance caused the gains.
• PTSystematic Review2016Systematic review of published studies on aquatic exercise for balance in patients with multiple sclerosis, Parkinson's disease, and hemiplegia.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoAquatic exercise may improve balance short term in multiple sclerosis and after stroke, but evidence for Parkinson's disease is too limited to support it. It is not clearly better than land-based exercise.
• PTOther2016Relationship Between Walking Capacity, Biopsychosocial Factors, Self-efficacy, and Walking Activity in Persons Poststroke.Journal of neurologic physical therapy : JNPTIn people after stroke who could walk independently, daily steps were linked to walking balance, comorbidity burden, and self-efficacy. When balance confidence was low, better walking capacity related more strongly to more steps.
• PTRCT2016Alterations in Aerobic Exercise Performance and Gait Economy Following High-Intensity Dynamic Stepping Training in Persons With Subacute Stroke.Journal of neurologic physical therapy : JNPTHigh-intensity stepping training did not reduce oxygen cost of walking in subacute stroke, but it increased highest oxygen use during treadmill testing and improved walking speed and distance compared with conventional therapy.
• PTOTCase-Control2016Study of acceleration of center of mass during sit-to-stand and stand-to-sit in patients with stroke.Journal of physical therapy sciencePatients with stroke took longer and showed reduced center of mass acceleration during sit-to-stand compared to healthy controls. During stand-to-sit, only side-to-side acceleration and time differed. This suggests training should address all balance directions for standing up, but focus on side-to-side stability for sitting down.
• PTOther2016Immediate effects of rhythmic auditory stimulation on gait in stroke patients in relation to the lesion site.Journal of physical therapy scienceAfter a single session of rhythmic auditory cues, walking speed and stride length increased in patients with cerebellum, pons and medulla, or thalamus lesions. In putamen or corona radiata lesions, the increases were not clear.
• PTCase Report2016The effects of backward walking training on balance and mobility in an individual with chronic incomplete spinal cord injury: A case report.Physiotherapy theory and practiceOne woman with chronic incomplete spinal cord injury improved balance and mobility after 18 backward walking sessions. Her Berg Balance score rose from 20/56 to 37/56, but walking independence did not change.
• PTOther2016Comparison of bone density on the dominant and nondominant sides between healthy elderly individuals and stroke patients.Journal of physical therapy scienceHealthy elderly controls showed no side-to-side difference in heel bone density. Stroke patients had lower bone density on the paretic side than the nonparetic side, and their side-to-side difference was larger than in controls.
• PTPilot2016Clinical usefulness of brain-computer interface-controlled functional electrical stimulation for improving brain activity in children with spastic cerebral palsy: a pilot randomized controlled trial.Journal of physical therapy scienceBoth groups showed increased brain-wave activity after six weeks. The supplied table marks within-group changes, so it does not show BCI-FES was better than FES.
• PTOther2016Effects of upper extremity training in a standing position on trunk alignment in stroke patients.Journal of physical therapy scienceIn 12 stroke patients, upper limb tasks done while standing reduced forward rounding of the upper back more than the same tasks done while sitting. The lower back curve did not show this change.
• PTRCT2016Effects of 8 weeks of mat-based Pilates exercise on gait in chronic stroke patients.Journal of physical therapy scienceIn chronic stroke patients, the Pilates group showed faster walking and longer strides after 8 weeks, but imbalance between sides did not improve.
• PTOther2016Primary and secondary gait deviations of stroke survivors and their association with gait performance.Journal of physical therapy scienceFive stroke survivors had less ankle, knee, and hip motion than five healthy controls, but more pelvic tilt, rotation, and side-to-side movement. On the affected side, knee, hip, and pelvic motion were seen with slower walking and shorter steps.
• PTRCT2016Effects of ankle biofeedback training on strength, balance, and gait in patients with stroke.Journal of physical therapy scienceAnkle strength did not differ between biofeedback training and conventional strengthening. Balance improved and walking time decreased more with biofeedback training after 8 weeks.
• PTOTCohort2016The effects of hand strength on upper extremity function and activities of daily living in stroke patients, with a focus on right hemiplegia.Journal of physical therapy scienceIn stroke patients with right hemiplegia, grip strength correlated with both upper extremity function and daily living independence. Pinch strength correlated with function but not with daily living tasks. Grip appears more critical for basic independence than finger pinch.
• PTOther2017Gait initiation is impaired in subjects with Parkinson's disease in the OFF state: Evidence from the analysis of the anticipatory postural adjustments through wearable inertial sensors.Gait & postureIn people with Parkinson's who were off medication, wearable sensors measured balance preparation before stepping in agreement with force plates and showed smaller side-to-side trunk movement and longer weight transfer than controls.
• PTSystematic Review2016Measurement properties of the upright motor control test for adults with stroke: a systematic review.Archives of physiotherapyIn adults with stroke, knee extension and knee flexion scores on the Upright Motor Control Test may help tell community walkers from household walkers. No published data showed whether different clinicians score it the same or whether it tracks change.
• PTCase Report2016Sustained effects of once-a-week gait training with hybrid assistive limb for rehabilitation in chronic stroke: case study.Journal of physical therapy scienceOne woman with chronic stroke improved walking speed by 72.7% after eight weeks of once-a-week robotic gait training. These gains remained at 51.7% two months later. This single case suggests sustained benefit but cannot prove the treatment works for others.
• PTSLPRCT2016Effects of an upper-limb exercise program for improving muscular strength and range of movement on respiratory function of stroke patients.Journal of physical therapy scienceAdding 30 minutes of upper-limb training to standard physiotherapy for four weeks significantly improved lung capacity, breathing volume, and cough strength in stroke patients compared to standard care alone.
• PTCase Report2016Prone positioning reduces severe pushing behavior: three case studies.Journal of physical therapy scienceThree stroke patients with severe pushing behavior had lower scores after 10-minute prone relaxation added to visual feedback, sit-to-stand and knee-ankle-foot orthotic gait training; scores remained lower at follow-up. Prone relaxation cannot be separated from these other treatments.
• PTOTOther2016Information on functioning found in the medical records of patients with stroke.Journal of physical therapy scienceStroke admission and discharge summaries mostly captured body function information, including muscle power and pain, and also walking, medication and imaging, while social participation and hobbies were absent.
• PTCase-Control2016180° turn while walking: characterization and comparisons between subjects with and without stroke.Journal of physical therapy sciencePeople with stroke took longer, used more steps, and lost balance more often during turns than matched healthy controls. Turning toward either side made no difference.
• PTSLPOther2016The correlation of respiratory muscle strength and cough capacity in stroke patients.Journal of physical therapy scienceIn stroke patients receiving general physical therapy, including neurological treatment, cough peak flow gains after inspiratory and expiratory muscle training tracked most closely with expiratory strength gains. Both cough peak flow and respiratory muscle strength increased.
• PTOTSurvey2016Evaluation of sensory processing abilities following stroke using the adolescent/adult sensory profile: implications for individualized intervention.Journal of physical therapy scienceStroke survivors mostly resembled healthy adults on sensory processing. They differed in low registration, sensation seeking, and sensation avoiding, not in sensory sensitivity. The profile describes patterns, not treatment effects.
• PTOther2016Relation between muscle fiber conduction velocity and exerted dynamic characteristics of muscular tension in patients with hemiplegia caused by stroke.Journal of physical therapy scienceThe affected leg in 13 people after stroke had slower electrical conduction in muscle fibers and weaker, slower ankle dorsiflexion force. On the affected side, slower conduction tracked with weaker, slower force, but the unaffected side showed no such link.
• PTOTCase-Control2017Effectiveness of robotic-assisted gait training in stroke rehabilitation: A retrospective matched control study.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoAdding RAGT to traditional physiotherapy did not produce a larger gain in daily living independence than traditional physiotherapy alone. It was associated with larger gains in walking, mobility, and balance.
• PTOther2017Are the average gait speeds during the 10meter and 6minute walk tests redundant in Parkinson disease?Gait & postureFor people with Parkinson disease, comfortable short-distance walking speed closely matched long-distance walking speed, especially at moderate stages. The comfortable short test may estimate the long test. Fast short-distance speed still gave separate information.
• PTCase Report2016Abnormal bias in subjective vertical perception in a post-stroke astasia patient.Journal of physical therapy scienceIn one man who could not stand after stroke, wall-based body-tilt training was added to ongoing gait and rehabilitation. Better vertical perception and longer standing followed. He stood 34 seconds with eyes open without a cane. One case is not proof.
• PTOther2016Impact of the difference in the plantar flexor strength of the ankle joint in the affected side among hemiplegic patients on the plantar pressure and walking asymmetry.Journal of physical therapy scienceStroke patients with weaker affected-side ankle plantar flexors showed greater walking asymmetry: shorter affected-side gait lines and lower affected-side forefoot and midfoot pressures than the unaffected side. This was an observational comparison, not a treatment trial.
• PTOther2016The effects of exercise on the GAP-43 expression in the spinal cord of arthritis-induced rats.Journal of physical therapy scienceTreadmill exercise increased a spinal cord protein linked to nerve repair in rats with knee arthritis. It does not show exercise reduces pain in people.
• PTOTCase Report2016Application of a tri-axial accelerometry-based portable motion recorder for the quantitative assessment of hippotherapy in children and adolescents with cerebral palsy.Journal of physical therapy scienceThree children and adolescents with cerebral palsy showed improved walking speed, step length, and balance control after two years of weekly hippotherapy. A portable motion recorder detected these gains immediately after sessions and over time. This small case series supports hippotherapy's potential benefits but cannot prove efficacy for the broader CP population.
• PTRCT2016Influence of biofeedback weight bearing training in sit to stand to sit and the limits of stability on stroke patients.Journal of physical therapy scienceStroke inpatients doing biofeedback weight-bearing training stood up and sat down faster and increased stability limits compared with functional weight-bearing training. Both groups also had standard physical therapy including CNS development therapy before the experiment, so the biofeedback component cannot be separated.
• PTOther2016An analysis of pulmonary function in different lying positions in the 20's normal adults.Journal of physical therapy scienceMeasured vital capacity was largest lying on the back and smallest lying face down in healthy young adults. Side-lying values were between them. This is a positioning observation, not proof that a treatment improves breathing.
• PTRCT2016Effects of virtual reality training using Nintendo Wii and treadmill walking exercise on balance and walking for stroke patients.Journal of physical therapy scienceAfter training, both Wii and treadmill programs lowered standing balance percentages; Wii training, which included yoga, strength, aerobic, and balance tasks, also increased walking cadence. The study was small and included only patients who could already stand and walk independently.
• PTPilot2016Effects of proprioceptive sense-based Kinesio taping on walking imbalance.Journal of physical therapy scienceKinesio tape on the affected side was followed by smaller left-right walking deviation after each of three taping conditions in 12 stroke patients with hemiplegia. Without a control group, this cannot show the tape caused the change.
• PTOTRCT2017Effects of 2 Years of Exercise on Gait Impairment in People With Parkinson Disease: The PRET-PD Randomized Trial.Journal of neurologic physical therapy : JNPTTwo years of either progressive resistance or multimodal balance exercise improved fast walking speed and step frequency in Parkinson's. Neither type was superior, but stride length and stability measures did not improve, and gait remained impaired relative to healthy controls.
• PTOTPilot2017Constraint-Induced Movement Therapy for Children With Brain Tumors.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy AssociationNine children with brain tumor hemiplegia completed all 15 constraint-induced movement therapy sessions. Quality of life scores did not show a clear change, but arm use improved and was mostly maintained at 3 months.
• PTProtocol2017The Interface of Clinical Decision-Making With Study Protocols for Knowledge Translation From a Walking Recovery Trial.Journal of neurologic physical therapy : JNPTTherapists adapted LEAPS walking protocols in post-stroke trial cases when shoulder pain or poor leg control threatened progression, using movement analysis, adjusted support, and pain-free exercise.
• PTCase Report2016The effect of a powered ankle foot orthosis on walking in a stroke subject: a case study.Journal of physical therapy scienceFor one stroke patient, a powered ankle-foot orthosis raised ankle and hip moments and stride length, but walking speed fell. This single case cannot show the device helps.
• PTOTSurvey2016Study on the quality of life of children with cerebral palsy.Journal of physical therapy scienceQuality of life in children with cerebral palsy was linked to mental function, pain, movement, self-care, school and social participation, and environmental barriers. These are daily-life and environment factors, not only movement.