TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

2,792 PAPERS · PAGE 31 OF 56 · NEWEST FIRST

• PTOTCohort2023Reliability and validity of the Hebrew version of the International Spinal Cord Injury Activities and Participation Basic Data Set.European journal of physical and rehabilitation medicineIn 47 people with spinal cord injury, the Hebrew activities and participation questionnaire gave similar answers when repeated, and self-care scores tracked disability well. Mobility, occupation, and relationship scores were less dependable, so interpret those parts cautiously.
• PTOTSLPCohort2023Does gender moderate the association between socioeconomic status and health? Results from an observational study in persons with spinal cord injury living in Morocco.Frontiers in rehabilitation sciencesHow people with spinal cord injury in Morocco felt about their social standing and financial hardship strongly predicted their health outcomes. Traditional markers like education and income did not. Gender did not significantly change these links, except for one finding on general health.
• PTOTOther2023Mobilizing registry data for quality improvement: A convergent mixed-methods analysis and application to spinal cord injury.Frontiers in rehabilitation sciencesStakeholders described spinal cord injury registry data use for quality improvement as supported by champions, patient input, audit and feedback, and linkage to electronic records, but limited by access, incomplete data, and workload.
• OTOther2023A novel assessment of participation and executive functions (A-PEX) for traumatic brain injury: a validity study.European journal of physical and rehabilitation medicineThe A-PEX tool reliably scores executive function deficits by observing a patient's actual participation in daily inpatient tasks. It distinguishes TBI patients from controls and correlates with standard cognitive tests. Scoring takes 30 to 45 minutes and does not fatigue the patient.
• PTOTCohort2023Postural control exercise without using the upper limbs improves activities of daily living in patients with stroke.Frontiers in rehabilitation sciencesStroke patients who practiced postural control without using their arms showed greater gains in daily living tasks and walking recovery than those who relied on arm support. This suggests training balance in more unstable conditions may improve functional independence.
• PTOTSLPNarrative Review2023Electrical stimulation methods and protocols for the treatment of traumatic brain injury: a critical review of preclinical research.Journal of neuroengineering and rehabilitationPreclinical reviews of electrical stimulation in animal models of traumatic brain injury report improvements in motor, cognitive, and arousal outcomes across four methods. However, inconsistent protocols and a lack of long-term data in these animal studies prevent direct application to human clinical practice.
• PTOTRCT2023Gait training with a wearable powered robot during stroke rehabilitation: a randomized parallel-group trial.Journal of neuroengineering and rehabilitationA wearable robot did not improve walking speed or distance more than standard therapist-assisted gait training in stroke patients. Both groups improved similarly, so the robot offers no clear advantage over conventional care for these primary outcomes.
• PTOTCohort2023Comparison of wrist actimetry variables of paretic upper limb use in post stroke patients for ecological monitoring.Journal of neuroengineering and rehabilitationWrist sensors worn at home for seven days showed that stroke patients with mild to moderate arm weakness made about 800 functional movements per day with their paretic arm versus 4,000 with the other. A ratio of these movements tracked arm impairment better than simple activity counts did.
• PTOTOther2023Dealing with the heterogeneous presentations of freezing of gait: how reliable are the freezing index and heart rate for freezing detection?Journal of neuroengineering and rehabilitationThe freezing index fails to separate freezing from voluntary stops and misfires on turns. Heart rate reliably distinguishes freezing from stops across all types. Combining a simple forward-motion metric with heart rate monitoring may improve home detection of freezing in Parkinson's disease.
• PTOTPilot2023Development of a compensation-aware virtual rehabilitation system for upper extremity rehabilitation in community-dwelling older adults with stroke.Journal of neuroengineering and rehabilitationThe virtual system did not beat conventional therapy on upper-limb function after three months, but both groups improved. It detected compensatory movements, though their counts did not fall.
• PTOTCase Series2023Epidural stimulation restores muscle synergies by modulating neural drives in participants with sensorimotor complete spinal cord injuries.Journal of neuroengineering and rehabilitationEpidural stimulation in six people with complete spinal cord injury reduced the number of muscle synergies to match healthy controls, indicating restored coordination. However, the left and right sides remained uncoordinated, and movement was less precise than in able-bodied individuals.
• OTRCT2023Traumatic Brain Injury Positive Strategies for Families: A Pilot Randomized Controlled Trial of an Online Parent-Training Program.Archives of physical medicine and rehabilitationCaregivers using the online TIPS program learned more strategies than those using a standard website, but they did not apply them better or report improved family quality of life. The program was highly rated and feasible, but it did not yet change patient or family outcomes.
• PTOTSystematic Review2023A systematic review of the applications of markerless motion capture (MMC) technology for clinical measurement in rehabilitation.Journal of neuroengineering and rehabilitationMarkerless video can capture body movement in rehab patients, but the review found the evidence too small and varied to support routine clinical measurement.
• PTOTSLPQualitative2023"If you respect me, you are respecting my culture": methods and recommendations for personalizing a TBI transitional care intervention.Brain injuryPatients and caregivers prioritized autonomy and respect over cultural matching. They wanted to choose their own goals and language, and sought an interventionist who could navigate the health system for them, rather than one who shared their specific cultural background.
• PTOTSLPSurvey2023Expected Health Benefits as the Ultimate Outcome of Information Available on Stroke Engine, a Knowledge Translation Stroke Rehabilitation Website: Web-Based Survey.JMIR rehabilitation and assistive technologiesStroke Engine users reported finding information relevant and learning something new. Some reported intending to use it and expecting health benefits, but this was a voluntary website survey, not proof that reading it improves stroke care.
• OTCohort2023Chronic frontal neurobehavioural symptoms in combat-deployed military personnel with and without a history of blast-related mild traumatic brain injury.Brain injuryAt 5 years, blast-related mild TBI military personnel self-reported clinically elevated overall frontal behavior symptoms and executive dysfunction symptoms, and higher disinhibition and apathy ratings than combat controls without TBI or blast.
• PTOTSLPPilot2023An educational intervention to promote a culture of gender equity among persons with traumatic brain injury and caregivers: A pilot study.Frontiers in rehabilitation sciencesA lecture-based session improved knowledge and skills in people with TBI, but an interactive version did not. The control group also showed gains, so the specific effect of the education remains unclear in this small pilot.
• PTOTSLPOther2023Predicting Motor Outcomes Using Atlas-Based Voxel Features of Post-Stroke Neuroimaging: A Scoping Review.Neurorehabilitation and neural repairAtlas-based brain imaging methods for predicting stroke motor recovery are currently unfit for clinical practice. The 17 studies reviewed used widely varying methods, small samples, and lacked validation, making results impossible to compare or apply to patient care.
• PTOTSLPNarrative Review2023Oropharyngeal Dysphagia in Acute Cervical Spinal Cord Injury: A Literature Review.DysphagiaDysphagia is common after cervical spinal cord injury, often silent and linked to tracheostomy, surgery, or respiratory impairment. Screening must account for reduced sensation. Specialist speech-language pathology input is recommended for assessment and tailored rehabilitation.
• PTOTSLPCohort2023The impact of cognitive function deficits and their recovery on functional outcome in subjects affected by ischemic subacute stroke: results from the Italian multicenter longitudinal study CogniReMo.European journal of physical and rehabilitation medicinePatients who recovered executive function during rehab improved their independence as much as those who never had a deficit. Those who kept the deficit improved significantly less. Screening for and targeting executive function may be key to functional recovery.
• PTOTRCT2023Motor Activated Auricular Vagus Nerve Stimulation as a Potential Neuromodulation Approach for Post-Stroke Motor Rehabilitation: A Pilot Study.Neurorehabilitation and neural repairPairing ear stimulation with movement did not beat unpaired stimulation for stroke arm recovery. Both groups improved similarly. The trial was too small to prove which method works better, so do not change your practice based on this pilot alone.
• OTCohort2023Brain regions associated with Brunnstrom and functional independence measure scores in patients after a stroke: a tract-based spatial statistics study.Journal of physical therapy scienceAfter stroke, motor severity was linked to damage in main motor pathways, while cognitive independence was linked to damage in wider connecting pathways. This suggests motor and cognitive deficits involve partly separate brain systems.
• PTOTOther2023Reliability, Validity, and Responsiveness of the Patient-Specific Functional Scale for Measuring Mobility-Related Goals in People With Multiple Sclerosis.Journal of neurologic physical therapy : JNPTThe Patient-Specific Functional Scale reliably tracks mobility goals in multiple sclerosis. A score improvement of 2.5 points signals the patient feels much better. This tool captures personal goals that standard walking tests miss, making it useful for tracking individual progress.
• PTOTCohort2023Predictive discriminative accuracy of walking abilities at discharge for community ambulation levels at 6 months post-discharge among inpatients with subacute stroke.Journal of physical therapy scienceWalking tests at discharge predict community ambulation six months later. A 6-minute walk distance of 299 meters or a walking speed of 0.94 meters per second best identified patients who would become unlimited community walkers. These cut-offs help set realistic goals for subacute stroke patients.
• PTOTQualitative2023The impact of rehabilitation on the community life of stroke survivors in Accra, Ghana.The South African journal of physiotherapyStroke survivors in Ghana reported improved self-care after six months of physiotherapy, but most could not return to work or socialize. They avoided public life due to embarrassment about visible disabilities, not just physical limits. This highlights a gap in psychosocial support within current rehabilitation services.
• OTCohort2023Reliability and validity of the Spanish adaptation of the Functional Independence Measure + Functional Assessment Measure.European journal of physical and rehabilitation medicineThe Spanish FIM+FAM measured functional independence after stroke consistently. Two raters agreed almost perfectly, and scores tracked other disability and mobility measures. It is best used for overall independence, not as a detailed cognitive or communication test.
• PTOTMeta-Analysis2023Exercise dosage to facilitate the recovery of balance, walking, and quality of life after stroke.The South African journal of physiotherapyHigh-dose aerobic exercise in hospital settings significantly improved walking capacity after stroke, but did not improve balance. Combining aerobic and resistance training improved quality of life. Therapists should prescribe at least 120 minutes per week at 60% heart rate reserve for walking recovery.
• PTOTOther2023Novel evaluation of upper-limb motor performance after stroke based on normal reaching movement model.Journal of neuroengineering and rehabilitationA new method estimates a stroke patient's normal reaching ability using their stronger arm, then maps the weaker arm's performance against this personal baseline. It identifies specific directions and distances where movement is most impaired, offering a visual guide for targeted robotic training.
• PTOTCohort2023Impairments of the arm and hand are highly correlated during subacute stroke.Journal of rehabilitation medicineArm and hand impairments in subacute stroke are highly correlated, with most patients scoring within one point of each other on clinical scales. Clinicians should not assume the hand is worse than the arm; assessing one segment often provides sufficient information about the other.
• PTOTPilot2023Autonomous Control of Music to Retrain Walking After Stroke.Neurorehabilitation and neural repairOne 30-minute session of automated, music-based gait training improved walking symmetry and reduced energy cost in 10 stroke survivors. The system adjusted music tempo and beat salience in real time based on foot sensors, offering a potential way to deliver skilled gait rehab without a therapist present.
• PTOTCohort2023Natural Walking Intensity in Persons With Parkinson Disease.Journal of neurologic physical therapy : JNPTHigh daily step counts in Parkinson's disease do not guarantee moderate intensity walking. Most participants accumulated minutes at very low intensities, with few reaching the 150-minute weekly target. Clinicians should ask patients directly about brisk walking rather than relying solely on step counts.
• PTOTOther2023System identification: a feasible, reliable and valid way to quantify upper limb motor impairments.Journal of neuroengineering and rehabilitationRobotic elbow perturbations took about 25 min and were tolerable, but stiffness measures were inconsistent and only weakly matched the impairment tests.
• PTOTSLPNarrative Review2023Proportional Recovery After Stroke: Addressing Concerns Regarding Mathematical Coupling and Ceiling Effects.Neurorehabilitation and neural repairStroke recovery is not just a measurement problem, according to this review. Baseline upper limb impairment still predicts how much function returns, but the Fugl-Meyer scale cannot measure recovery above its top score.
• OTCohort2023Grasp Analysis in the Home Environment as a Measure of Hand Function After Cervical Spinal Cord Injury.Neurorehabilitation and neural repairHome video showed people with cervical spinal cord injury used different grasp types at different rates. More non-prehensile grasp use went with lower hand strength and self-care scores, while more power grasp went with higher scores.
• PTOTCohort2023Rural-urban disparities in healthcare factors and long-term health outcomes in individuals with pediatric-onset spinal cord injury.Frontiers in rehabilitation sciencesAdults with pediatric-onset spinal cord injury living in rural areas reported more pressure injuries, urinary tract infections, bowel incontinence, hospitalizations, and sleep difficulties than their urban counterparts. They also faced lower employment and insurance rates. However, there were no differences in depression, anxiety, or life satisfaction between the groups.
• PTOTSLPCohort2023Influence of visual symptoms on posturographic performance after stroke.CoDASStroke survivors with visual symptoms showed significantly worse balance when relying on vision, unlike those without such symptoms. This suggests these patients struggle to use visual cues for stability. Assessing visual complaints is crucial before prescribing balance exercises that rely on sight.
• PTOTOther2023Quantitative measurement of finger usage in stroke hemiplegia using ring-shaped wearable devices.Journal of neuroengineering and rehabilitationA ring device objectively measured finger use in 20 stroke patients, showing affected hands were used less. However, this objective data did not match patients' self-reported use on the Motor Activity Log, suggesting subjective interviews may not accurately reflect real-world finger movement.
• PTOTSLPPilot2023The Community Rehabilitation Assessment: patient and clinician-reported outcomes in ambulatory rehabilitation.Frontiers in rehabilitation sciencesPatients in ambulatory rehab showed large improvements in daily activities and walking speed. The new assessment captured these changes, but without a control group, it is unclear how much was due to treatment versus natural recovery.
• PTOTOther2023Cognitive Impairments After Stroke Do Not Attenuate Explicit Visuomotor Adaptation in Reaching and Savings With the Unaffected Arm.Neurorehabilitation and neural repairStroke participants using their unaffected arm adapted to a 40° reaching rotation and relearned it as well as age-matched controls, despite lower cognitive screening scores. Both older groups were less accurate than young controls.
• PTOTOther2023The Swedish King's Parkinson's disease Pain Scale: Validation and pain prevalence in persons with mild-moderate severity Parkinson's disease.Journal of rehabilitation medicineThe Swedish King's Parkinson's Pain Scale correlates strongly with visual pain scores and captures pain independently of balance. In mild-moderate Parkinson's, 57% reported pain, mostly musculoskeletal. Use this scale to identify pain types that require specific rehabilitation strategies.
• OTPilot2023Measuring Arm and Hand Joint Kinematics to Estimate Impairment During a Functional Reach and Grasp Task after Stroke.Neurorehabilitation and neural repairStroke participants with similar arm function scores showed very different joint movement patterns on a sensor glove. The glove can map arm and hand joint movement patterns, but this small pilot did not test whether it improves therapy.
• PTOTSLPSystematic Review2023Environmental determinants for participation among stroke survivors in Africa, a scoping review.Frontiers in rehabilitation sciencesStroke survivors in Africa faced severe environmental barriers to participation. Inaccessible transport, buildings, and homes restricted mobility and therapy access. While family support was often positive, societal stigma and lack of assistive devices hindered reintegration. These factors drove survivors to self-imposed isolation.
• OTOther2023Eye-tracking control of an adjustable electric bed: construction and validation by immobile patients with multiple sclerosis.Journal of neuroengineering and rehabilitationThe eye-tracking bed-control system let patients with MS change bed positions, but they were slower and less efficient than controls. Practice helped, and seven of 16 who could use it preferred it.
• PTOTSLPCohort2023Switching attention deficits in post-stroke individuals with different aphasia types.AphasiologyPeople with non-fluent aphasia made more errors and responded slower than controls when switching attention between tones. People with fluent aphasia also made more errors but responded at normal speeds. These deficits occurred even without language tasks, suggesting attention problems are distinct from language loss.
• PTOTQualitative2023Perspectives of users for a future interactive wearable system for upper extremity rehabilitation following stroke: a qualitative study.Journal of neuroengineering and rehabilitationTherapists and stroke survivors want wearable systems that adapt to each person's specific impairment level and goals. They prioritized devices that track both the quality and quantity of movement, capturing compensatory trunk motions during functional tasks like dressing or cooking.
• PTOTSLPPilot2023Cognitive-motor dual-task interference in adults with sickle cell disease.Gait & postureMost adults with sickle cell disease slowed down when walking and talking. They often prioritized the conversation over their gait. This dual-task assessment was feasible and acceptable. It may help identify functional decline earlier in this population.
• OTOther2023Development of a Swedish short version of the Montreal Cognitive Assessment for cognitive screening in patients with stroke.Journal of rehabilitation medicineThe short Swedish MoCA, at a score of ≤12, correctly identified 97.41% of stroke patients with cognitive impairment, but it is a screening test, not a diagnosis.
• OTQualitative2023Stakeholders' Expectations of Return-to-Work After Spinal Cord Injury: A 1-Year Follow-Up.OTJR : occupation, participation and healthWorkers with spinal cord injuries felt pressured to match their pre-injury productivity, while employers struggled to adjust expectations to new physical and cognitive limits. Both groups bypassed rigid insurance regulations to make part-time work sustainable, hiding the true schedule from authorities.
• PTOTOther2023Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium.Journal of neuroengineering and rehabilitationA lower-back wearable could identify walking bouts, steps, and cadence reasonably well in real life, but stride length was unreliable, especially for slow or short bouts.
• OTCase-Control2023Prism Adaptation Treatment for Right-Sided and Left-Sided Spatial Neglect: A Retrospective Case-Matched Study.Archives of rehabilitation research and clinical translationPatients with right-sided neglect gained more on the neglect severity scale than those with left-sided neglect after prism adaptation. However, functional independence gains and discharge outcomes were identical between the two groups.