PTCase SeriesJournal of neuroengineering and rehabilitation2026

User preference in the personalized control of an ankle prosthesis: a case study.

María Alejandra Díaz, Stefano Nuzzo, Louis Flynn and 3 others

PMID 41862929

WHAT IT FOUND

Three transfemoral amputees chose preferred ankle push-off settings within 110 to 300 seconds.

Their choices often matched lower muscle effort in specific sound-limb muscles and better stride coordination, but not always the lowest overall effort.

Key findings

01Participants found preferred settings within 110 to 300 seconds and tested no more than 14 settings per trial.

02Preferred settings did not always match the lowest total muscle intensity, but they were associated with reduced activity in specific muscles.

03Within each participant, preferred settings consistently showed lower muscle synergy variability, reflecting better stride coordination.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Only three participants were studied, and all were high-functioning K3 or higher users of passive prostheses, so the findings may not apply to less mobile amputees or people new to prostheses. They had only one three-hour familiarization session, so preference may have reflected unfamiliarity with active ankle assistance rather than a stable long-term choice. The sample size was too small for statistical analysis, so the results are descriptive observations. Walking speed was fixed, and previous work suggests speed can influence preferred magnitude, so faster or slower walking might change the settings chosen. Ankle torque was estimated from motor position and ankle angle, not directly controlled, so torque comparisons across participants and trials are uncertain. The knee was kept overextended during stance, so the study tested ankle push-off only, not full knee-ankle control. Participants did not explore the full grid, and high assistance magnitudes were rarely tested, so the preferred area is imprecise.

The easy way to misread this

Do not conclude that personalized powered ankle prosthesis control improves mobility or that muscle activity determines user preference. Three high-functioning participants, one familiarization session, fixed treadmill speed, and no statistical analysis mean these are descriptive observations, and long-term passive prosthesis use may have shaped their choices.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →