OTSystematic ReviewJournal of intellectual disability research : JIDR2025

Substance Use and Problem Gambling Interventions for People With Intellectual Disability: A Systematic Review.

Amalia Udeanu, Gloria Garcia-Fernandez, Andrea Krotter and 3 others

PMID 40616464

WHAT IT FOUND

Evidence for substance use and gambling interventions in people with intellectual disability is thin: 16 small studies showed some short-term smoking reductions, mixed alcohol findings, and gambling was only one case report.

Key findings

01The review included 16 studies with 361 participants, but only three were randomised controlled trials.

02The mindfulness smoking trial reported fewer cigarettes per week in the mindfulness group than in the control group at follow-up.

03Alcohol randomised trials did not find significant differences between intervention and control groups.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

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What it does not show

The review included only 16 studies, and most were small case studies or non-randomised designs rather than randomised trials. Most participants were adults with mild to borderline intellectual disability, so the findings do not apply well to women or people with severe or profound intellectual disability. Many included studies had small samples, high dropout, short follow-up, or serious risk of bias, so their results are unstable. Gambling was represented by one case report, so it cannot show that a treatment works. The review excluded grey literature and studies not published in English or Spanish, and it did not calculate formal intercoder reliability, so relevant evidence may have been missed.

Declared interests

The authors declared no conflicts of interest. Funding was provided by the Spanish Government Delegation of the National Plan on Drugs, the University of Oviedo, and the Government of the Principality of Asturias.

The easy way to misread this

Do not conclude that mindfulness, CBT, or medication is an effective treatment for substance use or gambling in people with intellectual disability. The review found limited, poor-quality evidence, and gambling was only a single case report.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →