PTOtherJournal of physical therapy science2026

Study on the prevalence of sarcopenia and dynapenia in outpatient hemodialysis patients in urban areas of Japan: a multicenter cross-sectional study.

Sadami Asano, Akihiko Murayama, Seiichiro Nishida and 3 others

PMID 41700150

WHAT IT FOUND

In 177 Japanese haemodialysis outpatients, 35.6% had sarcopenia and 28.8% had dynapenia, meaning weakness with muscle mass intact.

Dynapenia was more common in women than men (40.5% vs 25.7%), and those patients had more muscle mass than those with sarcopenia.

Key findings

01Among 177 outpatients on haemodialysis, 63 (35.6%) had sarcopenia, 51 (28.8%) dynapenia, 9 (5.1%) presarcopenia, and 54 (30.5%) were classed as controls.

02Sarcopenia and dynapenia were both more common in women than in men: sarcopenia in 45.9% of women versus 32.9% of men, dynapenia in 40.5% versus 25.7%. No woman met the criteria for presarcopenia.

03Men with dynapenia were younger and had more muscle mass and a higher BMI than men with sarcopenia, yet their grip strength and sit-to-stand performance were clearly worse than controls'.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Participants were not randomly selected, so the four groups were not balanced for age and sex and the sample may not represent haemodialysis patients more generally. Only 37 women took part, and the authors say this was too few for reliable statistical analysis, so little can be concluded about women. Everyone was measured once, so the study cannot show whether weakness comes before muscle loss or whether treating one prevents the other. Data on cognitive function, education, socioeconomic status and where people lived were not collected, and the study period was short. All three dialysis centres belong to a single medical corporation in the Tokyo and Yokohama area, so the rates may not apply to other settings.

Declared interests

The authors state that they received no funding and declare no conflicts of interest.

The easy way to misread this

Do not read the 28.8% figure for dynapenia as showing that weakness is a stage on the way to muscle loss, or that spotting it early prevents anything. Everyone was measured once, so the study can say how common these states were, not what happens next. The sample was also not randomly selected, so the rates may not match your own dialysis unit.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →