PTSystematic ReviewArchives of rehabilitation research and clinical translation2025

Screening, Diagnosis, and Treatment of Cardiometabolic Risk in Persons With Spinal Cord Injury/Disease: A Scoping Review.

Luxshmi Nageswaran, Sarah Rosenbaum, Athena Ma and 4 others

PMID 41477070

WHAT IT FOUND

Most evidence in adults with spinal cord injury or disease mapped cardiometabolic risk rather than tested treatment.

Physical activity was the most studied intervention, but diet, medication, and behavior change evidence was sparse.

Key findings

01The review included 75 diagnosis studies, 28 therapy studies, 14 prognosis studies, and 4 harm studies.

02Physical activity was examined in 21 health-promoting behavior studies.

03Sociodemographic variables were reported in 37 studies, and income metrics were captured in less than 10% of studies.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Only English-language articles were included, so non-English evidence was not included. No cited reference searching was done, so some relevant studies may have been missed. The review protocol was not registered. Study type classification depended on reviewer interpretation, so some studies may have been placed differently. Most included studies were from high-income countries, and none were from low-income countries. Sociodemographic variables were poorly reported, and less than 10% of studies captured income metrics. No minimum sample size was required, so very small studies were included.

The easy way to misread this

Do not read this review as proof that physical activity reliably reduces cardiometabolic risk in spinal cord injury. It mapped 21 physical activity studies, but results were positive or no effect, and four studies used combined physical activity and electrical stimulation, so the contribution of each component cannot be separated.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →