Review of Intravenous Lipid Emulsion Therapy.
Jeffery W Spray
PMID 27828934WHAT IT FOUND
Nurses giving IV lipid emulsion should check egg allergy, product-specific filters, tubing changes, hang times, triglycerides, and liver tests.
This review gives practice points, not outcome evidence.
Key findings
01US intravenous lipid emulsions are an essential part of parenteral nutrition to prevent essential fatty acid deficiency, but current formulations have proinflammatory and immunosuppressive effects, and guidelines suggest withholding them for the first week of parenteral nutrition.
02In severe local anesthetic systemic toxicity, ASA describes lipid rescue as used along with supportive care, but does not recommend it at first signs or waiting until full cardiovascular collapse; current recommendations come from case reports and animal studies.
03For nursing administration, tubing for lipid infusions must be replaced within 24 hours, separately hung lipid emulsion has a 12-hour hang limit, 3-in-1 parenteral nutrition is stable for 20 hours once mixed, and precautions include checking egg allergy, triglycerides, and liver tests.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
Read the rest of this summary
You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.
What it does not show
The article is a narrative review, not an original study, and does not describe a systematic search or report outcomes. Lipid rescue recommendations are based on case reports and animal studies, so they do not establish tested efficacy. Product availability and guideline details are time-specific and may have changed since publication. The paper does not show whether the described monitoring or administration precautions prevent adverse events.
Declared interests
The authors declare no conflicts of interest.
The easy way to misread this
Do not read this review as proof that IV lipid emulsion or lipid rescue improves patient outcomes. It reports no original outcome data, and lipid rescue recommendations are described as based on case reports and animal studies.