SLPCohortThe Journal of head trauma rehabilitation2022

Research Letter: Impact of Obstructive Sleep Apnea Disease Duration on Neuropsychological Functioning After Traumatic Brain Injury: A Veterans Affairs TBI Model Systems Study.

Marc A Silva, Jaylene M Lee, Amanda Garcia and 2 others

PMID 35687890

WHAT IT FOUND

In 89 veterans with traumatic brain injury and obstructive sleep apnea, longer time since sleep apnea diagnosis was associated with worse delayed word recall.

Other brief cognitive tests, and having sleep apnea at all, were not associated with scores.

Key findings

01Longer time since OSA diagnosis was associated with worse delayed word list recall after controlling for age, education, and time to follow commands.

02OSA duration was not significantly associated with immediate word recall, digit span backwards, category fluency, number series, or backwards counting.

03Participants with OSA did not differ significantly from participants without OSA on any BTACT subtest.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

OSA diagnosis and duration were self-reported, not confirmed by records or polysomnography, so duration may be wrong and some people classified as OSA negative may have had undiagnosed OSA. The study did not have OSA severity or treatment data, so it cannot say whether treating OSA would change cognition. Six BTACT subtests were examined, and the paper states no correction for family-wise error was applied. The analytic sample was 89 veterans from one site, mostly male and White, and it differed from people lost or refused by being more likely Hispanic and having less severe TBI. Participants too impaired to complete testing were given the lowest possible scores. The timing of OSA diagnosis relative to TBI varied, and time living with OSA before diagnosis was unknown.

Declared interests

The supplied text does not include a conflict-of-interest declaration. Publication types list NIH and U.S. government research support.

The easy way to misread this

Do not conclude that obstructive sleep apnea caused worse delayed memory after TBI, or that treating it will improve memory. The study only linked longer self-reported duration since diagnosis to one test, and it did not show that people with OSA performed worse than people without OSA.

Read it on PubMed →