Rate of Force Development Is Related to Maximal Force and Sit-to-Stand Performance in Men With Stages 3b and 4 Chronic Kidney Disease.
Jared M Gollie, Michael O Harris-Love, Samir S Patel and 2 others
PMID 34708217WHAT IT FOUND
In men with advanced kidney disease, how quickly they could generate force in the first 50 milliseconds predicted how fast they could stand up, even though their maximum strength did not.
This suggests training should target speed of force, not just strength.
Key findings
01Early rate of force development (0-50 ms) was significantly associated with sit-to-stand time in the CKD group, but maximum voluntary force was not.
02Men with CKD had slower sit-to-stand times and lower maximum knee extensor strength compared to the reference group.
03Muscle echogenicity (a measure of muscle quality) was inversely related to late rate of force development in the CKD group.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTs
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What it does not show
The study had a very small sample size (13 CKD, 12 reference), limiting the generalizability of the findings. The study included only men, so results may not apply to women. The design was cross-sectional, so it cannot prove that improving rate of force development will directly improve sit-to-stand performance. Two participants in the CKD group were unable to perform the sit-to-stand test and were excluded from those analyses.
Declared interests
The study was funded by the Department of Veterans Affairs. The authors declared no commercial or financial conflicts of interest.
The easy way to misread this
Do not assume that improving maximum strength will automatically improve sit-to-stand speed in patients with advanced kidney disease. The study found that early rate of force development, not maximal strength, was the significant predictor of functional mobility in this group.