PTCase SeriesArchives of rehabilitation research and clinical translation2025

Radiographic Findings in the Lower Extremity Joints of Long-Term Users of Implanted Standing Neuroprostheses with Spinal Cord Injuries.

H Alex Hoyen, Sean Li, Michael Miller and 5 others

PMID 40678280

WHAT IT FOUND

No lower-extremity joint showed a significant change in arthritis grade in four long-term users of implanted standing neuroprostheses after spinal cord injury over an average of 51 months.

Key findings

01No joint among the 24 had a significant change in arthritis progression.

02Radiograph follow-up averaged 51 months.

03The knee was the only joint group with a slight, non-significant improvement.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Only four people were studied, so the result cannot be generalized to all users of implanted standing neuroprostheses. The participants were selected because they used the system very regularly; the authors say low-use individuals who developed joint changes could have been missed. The study included only four participants and used each participant's own radiographs as the comparison. The radiographs were taken without weight bearing, while the therapy is described as weight-bearing. The scoring systems were not necessarily described for joint changes after spinal cord injury, and rater agreement was moderate, with a kappa value of 0.42.

Declared interests

The authors have nothing to disclose.

The easy way to misread this

Do not conclude that implanted standing neuroprostheses are safe for joints in everyone with spinal cord injury. The study reports only four regular users, and the authors say low-use people with joint changes could have been missed.

Read it on PubMed →